오억수(吳億秀) 교수
생명과학과[대학원] /생명과학과
오억수 교수는 자연과학대학/생명과학전공 소속 교수로, 미국 알라바마대 세포생물학 전공으로 박사학위를 받았으며, 하버드 의과대학에서 박사후연수를 수행하였다. 주된 연구주제는 암미세환경에서 암발생 및 전이조절기전 연구이며 이를 바탕으로 암 진단 및 치료용 바이오마커 개발을 진행 중이다. 현재까지 관련분야에 총 90여편의 SCI 국제학술지를 발표하였으며 <J. Histochem. Cytochem>을 포함한 4종의 국제학술지 편집위원으로 활동하는 등 다양한 국내외 학술 활동을 하고 있다. 창업보육센터 소장을 역임하고 2014년 현재 연구처 처장 및 산학협력단 단장을 수행하고 있다.
- 종합과학관 C동 306호
- 02-3277-3761
- 면담 가능시간
- 월(9-12 시), 금 (2-5 시)
연구실적
- Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer MATRIX BIOLOGY, 2025, v.135, 125-134
- Arc-poration improves transdermal delivery of biomolecules Journal of Cosmetic Dermatology, 2024, v.23 no.6, 2240-2248
- Correlation of syndecan gene amplification with metastatic potential and clinical outcomes in carcinomas American journal of physiology. Cell physiology, 2024, v.327 no.2, C380-C386
- Everolimus exerts anticancer effects through inhibiting the interaction of matrix metalloproteinase-7 with syndecan-2 in colon cancer cells American Journal of Physiology - Cell Physiology, 2024, v.326 no.4, C1067-C1079
- Light-Dependent Circadian Rhythm Governs O-GlcNAc Cycling to Influence Cognitive Function in Adult Zebrafish Journal of Pineal Research, 2024, v.76 no.5, e13001
- Emerging role of syndecans in maintaining homeostasis of colon epithelium during inflammation American Journal of Physiology - Cell Physiology, 2022, v.322 no.5, C960-C966
- Shed syndecan-2 enhances colon cancer progression by increasing cooperative angiogenesis in the tumor microenvironment Matrix Biology, 2022, v.107, 40-58
- Substituted Syndecan-2-Derived Mimetic Peptides Show Improved Antitumor Activity over the Parent Syndecan-2-Derived Peptide International Journal of Molecular Sciences, 2022, v.23 no.11, 5888
- Colocalization with MMP-7 in the Distal Colon is Crucial for Syndecan-2 Shedding in Dextran Sulfate Sodium-Induced Colitis Mice JOURNAL OF INFLAMMATION RESEARCH, 2021, v.14, 4987-5000
- Extracellular Vesicles from Korean Codium fragile and Sargassum fusiforme Negatively Regulate Melanin Synthesis MOLECULES AND CELLS, 2021, v.44 no.10, 736-745
- Fam188b downregulation sensitizes lung cancer cells to anoikis via egfr downregulation and inhibits tumor metastasis in vivo Cancers, 2021 , 1-15
- Syndecan transmembrane domain specifically regulates downstream signaling events of the transmembrane receptor cytoplasmic domain International Journal of Molecular Sciences, 2021, v.22 no.15, 7918
- D-tyrosine adds an anti-melanogenic effect to cosmetic peptides Scientific Reports, 2020, v.10 no.1, 262
- Emerging Role of Syndecans in Extracellular Matrix Remodeling in Cancer Journal of Histochemistry and Cytochemistry, 2020, v.68 no.12, 863-870
- The oligomerization mediated by the alanine 397 residue in the transmembrane domain is crucial to sydecan-3 functions Cellular Signalling, 2020, v.69, 109544
- Therapeutic potential of chemically modified mir-489 in triple-negative breast cancers Cancers, 2020, v.12 no.8, 1-16
- Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance FEBS JOURNAL, 2019, v.286 no.15, 2870-2882
- Tannic acid attenuates the formation of cancer stem cells by inhibiting NF-kappa B-mediated phenotype transition of breast cancer cells AMERICAN JOURNAL OF CANCER RESEARCH, 2019, v.9 no.8, 1664-
- The melanocortin-1 receptor reversely regulates the melanin synthesis and migration of melanoma cells via dimerization-induced conformational changes Biochemical and Biophysical Research Communications, 2019, v.518 no.4, 739-745
- Tyrosine 51 residue of the syndecan-2 extracellular domain is involved in the interaction with and activation of pro-matrix metalloproteinase-7 Scientific Reports, 2019, v.9 no.1, 10625
- Up-regulation of syndecan-2 in proximal colon correlates with acute inflammation FASEB JOURNAL, 2019, v.33 no.10, 11381-11395
- D-tyrosine negatively regulates melanin synthesis by competitively inhibiting tyrosinase activity PIGMENT CELL & MELANOMA RESEARCH, 2018, v.31 no.3, 374-383
- Keratinocytes negatively regulate the N-cadherin levels of melanoma cells via contact-mediated calcium regulation BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, v.503 no.2, 615-620
- Syndecan transmembrane domain modulates intracellular signaling by regulating the oligomeric status of the cytoplasmic domain CELLULAR SIGNALLING, 2018, v.52, 121-126
- Inflammatory hypoxia induces syndecan-2 expression through IL-1 beta-mediated FOXO3a activation in colonic epithelia FASEB JOURNAL, 2017, v.31 no.4, 1516-1530
- Lipopolysaccharide (LPS)-stimulated iNOS induction is increased by glucosamine under normal glucose conditions but is inhibited by glucosamine under high glucose conditions in macrophage cells Journal of Biological Chemistry, 2017, v.292 no.5, 1724-1736
- Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress Scientific Reports, 2017, v.7 no.1
- Processing of syndecan-2 by matrix metalloproteinase-14 and effect of its cleavage on VEGF-induced tube formation of HUVECs Biochemical Journal, 2017, v.474 no.22, 3719-3732
- Screening of breast cancer stem cell inhibitors using a protein kinase inhibitor library Cancer Cell International, 2017, v.17 no.1
- Syndecan-2 cytoplasmic domain up-regulates matrix metalloproteinase-7 expression via the protein kinase C gamma-mediated FAK/ERK signaling pathway in colon cancer JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, v.292 no.39, 16321-16332
- Cytokeratin 18 is necessary for initiation of TGF-β1-induced epithelial–mesenchymal transition in breast epithelial cells Molecular and Cellular Biochemistry, 2016, v.423 no.42737, 21-28
- FK506 positively regulates the migratory potential of melanocyte-derived cells by enhancing syndecan-2 expression Pigment Cell and Melanoma Research, 2016, v.29 no.4, 434-443
- FK506 regulates pigmentation by maturing the melanosome and facilitating their transfer to keratinocytes Pigment Cell and Melanoma Research, 2016, v.29 no.2, 199-209
- Minireview: Syndecans and their crucial roles during tissue regeneration FEBS Letters, 2016, v.590
- New structural insight of C-terminal region of Syntenin-1, enhancing the molecular dimerization and inhibitory function related on Syndecan-4 signaling SCIENTIFIC REPORTS, 2016, v.6
- Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells Biochemical and Biophysical Research Communications, 2016, v.477 no.1, 47-53
- The conserved phenylalanine in the transmembrane domain enhances heteromeric interactions of syndecans Journal of Biological Chemistry, 2016, v.291 no.2, 872-881
- (E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol Enhances Melanogenesis through Increasing Upstream Stimulating Factor-1-Mediated Tyrosinase Expression PLOS ONE, 2015, v.10 no.11
- A Unique Phenylalanine in the Transmembrane Domain Strengthens Homodimerization of the Syndecan-2 Transmembrane Domain and Functionally Regulates Syndecan-2 JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, v.290 no.9, 5772-5782
- A combination of excimer laser treatment and topical tacrolimus is more effective in treating vitiligo than either therapy alone for the initial 6 months, but not thereafter Clinical and Experimental Dermatology, 2015, 24 Aug 2015
- Baicalin and baicalein inhibit transforming growth factor-β1-mediated epithelial-mesenchymal transition in human breast epithelial cells Biochemical and Biophysical Research Communications, 2015, v.458 no.3
- Endoplasmic reticulum stress as a novel target to ameliorate epithelial-to-mesenchymal transition and apoptosis of human peritoneal mesothelial cells Laboratory Investigation, 2015, v.95 no.10, 1157-1173
- Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: An Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis Molecular Carcinogenesis, 2015, v.54 no.5, 379-392
- Shed syndecan-2 enhances tumorigenic activities of colon cancer cells ONCOTARGET, 2015, v.6 no.6, 3874-3886
- Trans-regulation of syndecan functions by hetero-oligomerization Journal of Biological Chemistry, 2015, v.290 no.27, 16943-16953
- Interleukin-1 alpha, promotes extracellular shedding of syndecan-2 via induction of matrix metalloproteinase-7 expression BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, v.446 no.2, 487-492
- Keratinocyte-derived laminin-332 protein promotes melanin synthesis via regulation of tyrosine uptake Journal of Biological Chemistry, 2014, v.289 no.31, 21751-21759
- Matrix metalloproteinase-14 mediates cleavage of syndecan-2 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, v.34, S128-S128
- Syndecan-2 regulates melanin synthesis via protein kinase C beta II-mediated tyrosinase activation PIGMENT CELL & MELANOMA RESEARCH, 2014, v.27 no.3, 387-397
- Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes LABORATORY INVESTIGATION, 2014, v.94 no.10, 1114-1125
- [학술지논문] Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer MATRIX BIOLOGY, 2025, v.135 no.1 , 125-134
- [학술지논문] Arc-poration improves transdermal delivery of biomolecules JOURNAL OF COSMETIC DERMATOLOGY, 2024, v.23 no.6 , 2240-2248
- [학술지논문] Antifungal Activity of Bulgarian Rose Damascena Oil against Vaginitis-Causing Opportunistic Fungi EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2023, v.1 no.1 , 5054865-5054871
- [학술지논문] Synergistic Anti-Inflammatory Effects of Ethanol Extracts from Chrysanthemum zawadskii Flower and Cudrania tricuspidata Fruit Occur via Inhibition of the NF- κ B Signaling Pathway EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2023, v.22 no.1 , 1-9
- [학술지논문] Emerging role of syndecans in maintaining homeostasis of colon epithelium during inflammation AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, v.322 no.5 , C960-C966
- [학술지논문] Substituted Syndecan-2-Derived Mimetic Peptides Show Improved Antitumor Activity over the Parent Syndecan-2-Derived Peptide INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, v.23 no.11 , 5888-5888
- [학술지논문] Colocalization with MMP-7 in the Distal Colon is Crucial for Syndecan-2 Shedding in Dextran Sulfate Sodium-Induced Colitis Mice Journal of Inflammation Research, 2021, v.14 no.0 , 4987-5000
- [학술지논문] Extracellular Vesicles from Korean Codium fragile and Sargassum fusiforme Negatively Regulate Melanin Synthesis MOLECULES AND CELLS, 2021, v.44 no.10 , 736-745
- [학술지논문] FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo CANCERS, 2021, v.13 no.2 , 247-247
- [학술지논문] Syndecan Transmembrane Domain Specifically Regulates Downstream Signaling Events of the Transmembrane Receptor Cytoplasmic Domain INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.15 , 7918-7918
- [학술지논문] D-tyrosine adds an anti-melanogenic effect to cosmetic peptides SCIENTIFIC REPORTS, 2020, v.10 no.1 , 262-262
- [학술지논문] Emerging Role of Syndecans in Extracellular Matrix Remodeling in Cancer JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2020, v.68 no.12 , 863-870
- [학술지논문] The oligomerization mediated by the alanine 397 residue in the transmembrane domain is crucial to sydecan-3 functions CELLULAR SIGNALLING, 2020, v.69 no.1 , 109544-109556
- [학술지논문] Therapeutic Potential of Chemically Modified miR-489 in Triple-Negative Breast Cancers CANCERS, 2020, v.12 no.8 , 2209-2209
- [저역서] Syndecan-2 Biology and Its Role in Colorectal Carcinoma Springer, 2022, 493
강의
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2025-1학기
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세포생물학Ⅰ
- 학수번호 34229분반 01
- 3학년 ( 3학점 , 3시간) 화 6~6 (포361) , 목 4~4 (포361)
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생명과학실험Ⅲ
- 학수번호 35313분반 01
- 3학년 ( 2학점 , 3시간) 목 6~7 (종A203)
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생명과학실험Ⅲ
- 학수번호 35313분반 02
- 3학년 ( 2학점 , 3시간) 금 6~7 (종A203)
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조직세포학
- 학수번호 37121분반 01
- 4학년 ( 3학점 , 3시간) 화 4~4 (포361) , 금 5~5 (포361)
-
세포생물학특론Ⅱ
- 학수번호 G16951분반 01
- 학년 ( 3학점 , 3시간) 금 7~8 (종C)
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암생물학
- 학수번호 G16978분반 01
- 학년 ( 3학점 , 3시간) 화 5~6 (종C)
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2024-2학기
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일반생물학
- 학수번호 20412분반 07
- 1학년 ( 3학점 , 3시간) 수 3~3 (종A) , 금 2~2 (101)
- 팀티칭, 약학부1
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일반생물학실험Ⅱ
- 학수번호 33333분반 01
- 1학년 ( 1학점 , 1.5시간) 화 7~7 (종A203)
- 팀티칭, 제한 없음
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일반생물학실험Ⅱ
- 학수번호 33333분반 02
- 1학년 ( 1학점 , 1.5시간) 월 7~7 (종A203)
- 팀티칭, 제한 없음
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세포생물학Ⅱ
- 학수번호 34237분반 01
- 3학년 ( 3학점 , 3시간) 화 2~2 (포361) , 금 3~3 (포361)
- 팀티칭
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분자의생물학
- 학수번호 36336분반 01
- 4학년 ( 3학점 , 3시간) 월 4~4 (종A) , 목 5~5 (102)
- 팀티칭
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암생물학개론
- 학수번호 38220분반 01
- 4학년 ( 3학점 , 3시간) 화 4~4 (포453) , 금 5~5 (포453)
- 팀티칭
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세포생물학특론Ⅰ
- 학수번호 G16950분반 01
- 학년 ( 3학점 , 3시간) 금 4~5 (종C)
- 영어강의
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고급세포생물학
- 학수번호 G16993분반 01
- 학년 ( 3학점 , 3시간) 화 7~8 (종C)
-
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2024-1학기
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세포생물학Ⅰ
- 학수번호 34229분반 01
- 3학년 ( 3학점 , 3시간) 화 6~6 (포361) , 목 4~4 (포361)
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세포생물학Ⅰ
- 학수번호 34229분반 03
- 3학년 ( 3학점 , 3시간) 화 3~3 (포366) , 목 2~2 (포366)
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생명과학실험Ⅲ
- 학수번호 35313분반 01
- 3학년 ( 2학점 , 3시간) 목 6~7 (종A202)
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생명과학실험Ⅲ
- 학수번호 35313분반 02
- 3학년 ( 2학점 , 3시간) 금 6~7 (종A202)
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조직세포학
- 학수번호 37121분반 01
- 4학년 ( 3학점 , 3시간) 화 4~4 (포366) , 금 5~5 (포366)
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세포생물학특론Ⅱ
- 학수번호 G16951분반 01
- 학년 ( 3학점 , 3시간) 금 7~8 (종C)
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암생물학
- 학수번호 G16978분반 01
- 학년 ( 3학점 , 3시간) 화 5~6 (종C)
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2023-2학기
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일반생물학 강의 계획서 상세보기
- 학수번호 20412분반 03
- 1학년 ( 3학점 , 3시간) 월 6~6 (종A) , 수 5~5 (102)
- 자연대
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일반생물학실험Ⅱ 강의 계획서 상세보기
- 학수번호 33333분반 02
- 1학년 ( 1학점 , 1.5시간) 월 7~8 (종A203)
- 집중이수(8주) 수업
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세포생물학II 강의 계획서 상세보기
- 학수번호 34237분반 01
- 3학년 ( 3학점 , 3시간) 화 2~2 (포361) , 금 3~3 (포361)
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암생물학개론 강의 계획서 상세보기
- 학수번호 38220분반 01
- 4학년 ( 3학점 , 3시간) 화 4~4 (포453) , 금 5~5 (포453)
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생명과학연구Ⅳ
- 학수번호 G16935분반 01
- 학년 ( 3학점 , 3시간)
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세포생물학특론Ⅰ
- 학수번호 G16950분반 01
- 학년 ( 3학점 , 3시간) 금 4~5 (종C)
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고급세포생물학
- 학수번호 G16993분반 01
- 학년 ( 3학점 , 3시간) 화 7~8 (종C)
-
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2023-1학기
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일반생물학 강의 계획서 상세보기
- 학수번호 20412분반 03
- 1학년 ( 3학점 , 3시간) 월 2~2 (포453) , 목 3~3 (포453)
- 공대
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세포생물학I 강의 계획서 상세보기
- 학수번호 34229분반 01
- 3학년 ( 3학점 , 3시간) 화 6~6 (포361) , 목 4~4 (포361)
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세포생물학I 강의 계획서 상세보기
- 학수번호 34229분반 02
- 3학년 ( 3학점 , 3시간) 화 4~4 (포366) , 금 5~5 (포366)
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조직세포학 강의 계획서 상세보기
- 학수번호 37121분반 01
- 4학년 ( 3학점 , 3시간) 수 3~3 (포366) , 금 2~2 (포366)
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21C바이오산업 강의 계획서 상세보기
- 학수번호 37713분반 01
- 4학년 ( 1학점 , 1시간) 수 6~6 (포363)
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세포생물학특론Ⅱ
- 학수번호 G16951분반 01
- 학년 ( 3학점 , 3시간) 금 5~6 (종C)
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생명공학
- 학수번호 G16974분반 01
- 학년 ( 3학점 , 3시간) 수 5~6 (종C)
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2022-2학기
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일반생물학실험II
- 학수번호 33333분반 01
- 1학년 ( 1학점 , 1.5시간) 월 6~7 (종A202)
- 집중이수(8주) 수업
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일반생물학실험II
- 학수번호 33333분반 02
- 1학년 ( 1학점 , 1.5시간) 수 6~7 (종A202)
- 집중이수(8주) 수업
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세포생물학II
- 학수번호 34237분반 01
- 3학년 ( 3학점 , 3시간) 화 6~6 (포361) , 목 4~4 (포361)
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암생물학개론
- 학수번호 38220분반 01
- 4학년 ( 3학점 , 3시간) 화 4~4 (포453) , 금 5~5 (포453)
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생명과학세미나Ⅳ
- 학수번호 G16931분반 01
- 학년 ( 3학점 , 3시간) 목 3~4 (종C)
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생명과학연구Ⅳ
- 학수번호 G16935분반 01
- 학년 ( 3학점 , 3시간)
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고급세포생물학
- 학수번호 G16993분반 01
- 학년 ( 3학점 , 3시간) 화 7~8 (종C)
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2022-1학기
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일반생물학
- 학수번호 20412분반 02
- 1학년 ( 3학점 , 3시간) 화 3~3 (포453) , 목 2~2 (포453)
- AI융합학부 인공지능전공
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세포생물학I
- 학수번호 34229분반 01
- 3학년 ( 3학점 , 3시간) 화 6~6 (포452) , 목 4~4 (포452)
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세포생물학I
- 학수번호 34229분반 02
- 3학년 ( 3학점 , 3시간) 수 6~6 (포366) , 금 4~4 (포366)
-
생명공학
- 학수번호 G16974분반 01
- 학년 ( 3학점 , 3시간) 수 5~6
-
암생물학
- 학수번호 G16978분반 01
- 학년 ( 3학점 , 3시간) 월 5~6
-