Kyung Lim Lee Professor Emeritus
Prof. Kyunglim Lee has served Ewha Womans University since 1995 as a Professor in the department of Pharmacology. She is currently a Dean for the College of Pharmacy at Ewha Womans University, and the head of the Ewha Graduate School of Clinical Health Sciences and the Centers for Pharmacy Healthcare Communication (PHC). Prof. Lee is an authority on the field of Cell Physiology. She received her Ph.D. from Tufts University, USA in 1992 in the field of Biology and then spent her time at the Biochemistry & Molecular Biology Department of Harvard University, USA at a position of Post-doctoral fellow. Researches of Prof. Lee are currently focused on the study for the pathophysiological role of translationally controlled tumor protein (TCTP) in various diseases, such as allergy, hypertension, and cancer. Prof. Lee published research ariticles in SCI journals including Biomaterials, Oncogene, and Journal of Controlled Release and registration of several international patents. She has been holding a number of roles in academic societies and woman scientist’s societies, as a Director, Vice-President, or President and was appointed to the Editorial Board of ISRN Molecular Biology.
Research Record
- Cellular Uptake Mechanism of TCTP-PTD in Human Lung Carcinoma Cells Molecular Pharmaceutics, 2015, v.12 no.1, 194-203
- Translationally Controlled Tumor Protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasis SCIENTIFIC REPORTS, 2015, v.5
- A tryptophan-based assay method to search regulatory compounds for transcriptionally controlled tumor protein Biochemical and Biophysical Research Communications, 2024, v.692, 149363
- TAZ deficiency exacerbates psoriatic pathogenesis by increasing the histamine-releasing factor Cell and Bioscience, 2024, v.14 no.1, 60
- Inhibitors of dimerized translationally controlled tumor protein, a histamine releasing factor, may serve as anti-allergic drug candidates Biochimie, 2023, v.211, 141-152
- Meclizine, a piperazine-derivative antihistamine, binds to dimerized translationally controlled tumor protein and attenuates allergic reactions in a mouse model Biomedicine and Pharmacotherapy, 2023, v.157, 114072
- Targeting the translationally controlled tumor protein by a monoclonal antibody improves allergic airway inflammation in mice Biomedicine and Pharmacotherapy, 2023, v.168, 115655
- Translationally controlled tumor protein restores impaired memory and altered synaptic protein expression in animal models of dementia Biomedicine and Pharmacotherapy, 2023, v.160, 114357
- Dimeric translationally controlled tumor protein–binding peptide 2 attenuates imiquimod-induced psoriatic inflammation through induction of regulatory T cells Biomedicine and Pharmacotherapy, 2022, v.152, 113245
- PEGylation improves the therapeutic potential of dimerized translationally controlled tumor protein blocking peptide in ovalbumin-induced mouse model of airway inflammation Drug Delivery, 2022, v.29 no.1, 2320-2329
- Protein transduction domain of translationally controlled tumor protein: characterization and application in drug delivery DRUG DELIVERY, 2022, v.29 no.1, 3009-3021
- Role of Translationally Controlled Tumor Protein (TCTP) in the Development of Hypertension and Related Diseases in Mouse Models BIOMEDICINES, 2022, v.10 no.11, 2722
- Systemic and brain delivery of antidiabetic peptides through nasal administration using cell-penetrating peptides FRONTIERS IN PHARMACOLOGY, 2022, v.13, 1068495
- Allergic Inflammation Caused by Dimerized Translationally Controlled Tumor Protein is Attenuated by Cardamonin FRONTIERS IN PHARMACOLOGY, 2021, v.12, 765521
- Blockade of translationally controlled tumor protein attenuated the aggressiveness of fibroblast-like synoviocytes and ameliorated collagen-induced arthritis EXPERIMENTAL AND MOLECULAR MEDICINE, 2021 , 67-80
- Dimerized Translationally Controlled Tumor Protein-Binding Peptide 2 Attenuates Systemic Anaphylactic Reactions Through Direct Suppression of Mast Cell Degranulation FRONTIERS IN PHARMACOLOGY, 2021, v.12, 764321
- Overexpression of translationally controlled tumor protein ameliorates metabolic imbalance and increases energy expenditure in mice International Journal of Obesity, 2021, v.45 no.7, 1576-1587
- dTBP2 attenuates severe airway inflammation by blocking inflammatory cellular network mediated by dTCTP Biomedicine and Pharmacotherapy, 2021, v.144, 112316
- Flexible loop and helix 2 domains of TCTP are the functional domains of dimerized TCTP Scientific Reports, 2020, v.10 no.1, 197
- Regulation of Autophagy Is a Novel Tumorigenesis-Related Activity of Multifunctional Translationally Controlled Tumor Protein CELLS, 2020, v.9 no.1, 257
- Dimerized, Not Monomeric, Translationally Controlled Tumor Protein Induces Basophil Activation and Mast Cell Degranulation in Chronic Urticaria IMMUNE NETWORK, 2019, v.19 no.3, UNSP e20
- Enhanced intranasal insulin delivery by formulations and tumor protein-derived protein transduction domain as an absorption enhancer Journal of Controlled Release, 2019, v.294, 226-236
- Optimization of formulation for enhanced intranasal delivery of insulin with translationally controlled tumor protein-derived protein transduction domain Drug delivery, 2019, v.26 no.1, 622-628
- Radiosensitivity of Cancer Cells Is Regulated by Translationally Controlled Tumor Protein CANCERS, 2019, v.11 no.3, 386
- Dehydrocostus lactone, a sesquiterpene from Saussurea lappa Clarke, suppresses allergic airway inflammation by binding to dimerized translationally controlled tumor protein PHYTOMEDICINE, 2018, v.43, 46-54
- Dimerized translationally controlled tumor protein increases interleukin-8 expression through MAPK and NF-ΚB pathways in a human bronchial epithelial cell line Cell and Bioscience, 2018, v.8 no.1, 13
- Modification of translationally controlled tumor protein-derived protein transduction domain for improved intranasal delivery of insulin DRUG DELIVERY, 2018, v.25 no.1, 1025-1032
- Modified translationally controlled tumor protein-derived protein transduction domain enhances nasal delivery of exendin-4 as shown with insulin Drug Delivery, 2018, v.25 no.1, 1579-1584
- Some Biological Consequences of the Inhibition of Na,K-ATPase by Translationally Controlled Tumor Protein (TCTP) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, v.19 no.6
- Dimerized translationally controlled tumor protein-binding peptide ameliorates atopic dermatitis in NC/NGA mice International Journal of Molecular Sciences, 2017, v.18 no.2
- Immunohistochemical Localization of Translationally Controlled Tumor Protein in Axon Terminals of Mouse Hippocampal Neurons EXPERIMENTAL NEUROBIOLOGY, 2017, v.26 no.2, 82-89
- TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway AUTOPHAGY, 2017, v.13 no.5, 820-833
- Potential of Translationally Controlled Tumor Protein-Derived Protein Transduction Domains as Antigen Carriers for Nasal Vaccine Delivery MOLECULAR PHARMACEUTICS, 2016, v.13 no.9, 3196-3205
- Inactivation of Src-to-Ezrin pathway: A possible mechanism in the ouabain-mediated inhibition of A549 cell migration BioMed Research International, 2015, 2015
- Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells International Journal of Molecular Sciences, 2015, v.16 no.4, 7565-7576
- Dimerized Translationally Controlled Tumor Protein (TCTP) induces Interleukin-8 secretion in human bronchial epithelial cells via MAPK and NF-kappa B pathway PROTEIN SCIENCE, 2014, v.23, 83-84
- Interaction of translationally controlled tumor protein with Apaf-1 is involved in the development of chemoresistance in HeLa cells BMC CANCER, 2014, v.14, Article ID 165
- Osteoclastogenic activity of translationally-controlled tumor protein (TCTP) with reciprocal repression of p21 FEBS LETTERS, 2014, v.588 no.21, 4026-4031
- Up-regulation of RhoA/Rho kinase pathway by translationally controlled tumor protein in vascular smooth muscle cells International Journal of Molecular Sciences, 2014, v.15 no.6, 10365-10376
Courses
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2023-2nd
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Physiology 강의 계획서 상세보기
- Subject No 33950Class No 01
- 3Year ( 3Credit , 3Hour) Mon 5~5 (POSCO551) , Thu 6~6 (POSCO551)
- Major Requisite
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Physiology 강의 계획서 상세보기
- Subject No 33950Class No 02
- 3Year ( 3Credit , 3Hour) Mon 4~4 (POSCO551) , Thu 4~4 (POSCO551)
- Major Requisite
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Physiology 강의 계획서 상세보기
- Subject No 33950Class No 03
- 3Year ( 3Credit , 3Hour) Mon 6~6 (POSCO551) , Thu 5~5 (POSCO551)
- Major Requisite
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Anatomy and Physiology Ⅱ 강의 계획서 상세보기
- Subject No 38937Class No 01
- 2Year ( 3Credit , 3Hour) Tue 2~2 (POSCO551) , Fri 3~3 (POSCO551)
- Major Requisite
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Anatomy and Physiology Ⅱ 강의 계획서 상세보기
- Subject No 38937Class No 02
- 2Year ( 3Credit , 3Hour) Tue 3~3 (POSCO551) , Fri 2~2 (POSCO551)
- Major Requisite
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Anatomy and Physiology Ⅱ 강의 계획서 상세보기
- Subject No 39042Class No 01
- 2Year ( 3Credit , 3Hour) Tue 4~4 (POSCO551) , Fri 4~4 (POSCO551)
- Major Requisite
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2023-1st
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Anatomy 강의 계획서 상세보기
- Subject No 37104Class No 01
- 3Year ( 1.5Credit , 1.5Hour) Wed 5~5 (POSCO551)
- Major Requisite
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Anatomy 강의 계획서 상세보기
- Subject No 37104Class No 02
- 3Year ( 1.5Credit , 1.5Hour) Thu 4~4 (POSCO551)
- Major Requisite
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Anatomy 강의 계획서 상세보기
- Subject No 37104Class No 03
- 3Year ( 1.5Credit , 1.5Hour) Wed 4~4 (POSCO551)
- Major Requisite
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Pathophysiology 강의 계획서 상세보기
- Subject No 37125Class No 01
- 4Year ( 3Credit , 3Hour) Mon 2~2 (POSCO551) , Thu 2~2 (POSCO551)
- Major Requisite
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Pathophysiology
- Subject No 37125Class No 02
- 4Year ( 3Credit , 3Hour) Mon 4~4 (POSCO551) , Thu 6~6 (POSCO551)
- Major Requisite
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Pathophysiology
- Subject No 37125Class No 03
- 4Year ( 3Credit , 3Hour) Mon 3~3 (POSCO551) , Thu 3~3 (POSCO551)
- Major Requisite
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2022-2nd
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Physiology
- Subject No 33950Class No 01
- 3Year ( 3Credit , 3Hour) Mon 5~5 (POSCO551) , Thu 5~5 (POSCO551)
- Major Requisite
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Physiology
- Subject No 33950Class No 02
- 3Year ( 3Credit , 3Hour) Mon 3~3 (POSCO552) , Thu 4~4 (POSCO551)
- Major Requisite
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Physiology
- Subject No 33950Class No 03
- 3Year ( 3Credit , 3Hour) Mon 4~4 (POSCO552) , Thu 3~3 (POSCO551)
- Major Requisite
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Advanced Pharmacy Practice and Research I
- Subject No 37154Class No 02
- 6Year ( 4Credit , 200Hour)
- Major Requisite
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Seminar for Pharmaceutical Sciences IV
- Subject No G16889Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)
- Professor Determined
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Seminar for Pharmaceutical Sciences Ⅳ
- Subject No G18241Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)
- Professor Determined
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2022-1st
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Anatomy
- Subject No 37104Class No 01
- 3Year ( 1.5Credit , 1.5Hour) Tue 5~5
- Major Requisite
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Anatomy
- Subject No 37104Class No 02
- 3Year ( 1.5Credit , 1.5Hour) Wed 4~4
- Major Requisite
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Anatomy
- Subject No 37104Class No 03
- 3Year ( 1.5Credit , 1.5Hour) Wed 5~5
- Major Requisite
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Pathophysiology
- Subject No 37125Class No 01
- 4Year ( 3Credit , 3Hour) Mon 4~4 , Tue 3~3
- Major Requisite
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Pathophysiology
- Subject No 37125Class No 02
- 4Year ( 3Credit , 3Hour) Mon 5~5 , Thu 7~7
- Major Requisite
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Pathophysiology
- Subject No 37125Class No 03
- 4Year ( 3Credit , 3Hour) Tue 2~2 , Thu 3~3
- Major Requisite
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Pathophysiology
- Subject No 37125Class No 04
- 4Year ( 3Credit , 3Hour) Tue 2~2 , Thu 3~3
- Major Requisite
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Academic Background
Tufts University Ph.D.(생물학)