Research Record

• DRSPRING: Graph convolutional network (GCN)-Based drug synergy prediction utilizing drug-induced gene expression profile Computers in Biology and Medicine, 2024, v.174, 108436
  SCIE Scopus dColl.
• Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma Scientific Reports, 2024, v.14 no.1, 21096
  SCIE Scopus dColl.
• Glyoxalase 1: Emerging biomarker and therapeutic target in cervical cancer progression PLoS ONE, 2024, v.19 no.6, e0299345
  SCIE Scopus dColl.
• Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells Scientific reports, 2023, v.13 no.1, 2404
  SCIE Scopus dColl.
• Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord-Like Organoid (pSCO) with Dorsoventral Organization Advanced Science, 2023, v.10 no.20, 2301787
  SCIE Scopus dColl.
• A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population Experimental and Molecular Medicine, 2022, v.54, 1-10
  KCI dColl.
• Comprehensive Analysis of Alternative Splicing in Gastric Cancer Identifies Epithelial-Mesenchymal Transition Subtypes Associated with Survival Cancer Research, 2022, v.82 no.4, 543-555
  SCIE dColl.
• Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer npj Genomic Medicine, 2022, v.7 no.1, 63
  SCIE Scopus dColl.
• Fluid Shear Stress Regulates the Landscape of microRNAs in Endothelial Cell-Derived Small Extracellular Vesicles and Modulates the Function of Endothelial Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, v.23 no.3, 1314
  SCIE Scopus dColl.
• Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-Kappa B survival machinery in cancer cells Redox Biology, 2022, v.51, 102293
  SCIE Scopus dColl.
• Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells ONCOIMMUNOLOGY, 2022, v.11 no.1, 2015170
  SCIE Scopus dColl.
• Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ Layers Stem Cell Reviews and Reports, 2022, v.18 no.3, 1181-1192
  SCIE Scopus dColl.
• Production of human spinal-cord organoids recapitulating neural-tube morphogenesis Nature Biomedical Engineering, 2022, v.6 no.4, 435-448
  SCIE Scopus dColl.
• Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing Genomics and Informatics, 2021, v.19 no.1, e2
  Scopus dColl.
• FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress Cell Death and Disease, 2021, v.12 no.4, 407
  SCIE Scopus dColl.
• Genome-scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib-resistant lung cancer Molecular Oncology, 2021, v.15 no.2, 487-502
  SCIE Scopus dColl.
• Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells NEOPLASIA, 2021, v.23 no.9, 993-1001
  SCIE Scopus dColl.
• iCSDB: An integrated database of CRISPR screens Nucleic Acids Research, 2021 , D956-D961
  SCIE Scopus dColl.
• Angioimmunoblastic T-cell lymphoma-like lymphadenopathy in mice transgenic for human RHOA with p.Gly17Val mutation ONCOIMMUNOLOGY, 2020, v.9 no.1, 0
  SCIE Scopus dColl.
• Bioinformatics services for analyzing massive genomic datasets Genomics and Informatics, 2020, v.18 no.1, e8
  Scopus dColl.
• Characterization of TNNC1 as a Novel Tumor Suppressor of Lung Adenocarcinoma Molecules and cells, 2020, v.43 no.7, 619-631
  Scopus dColl.
• ChimerDB 4.0: an updated and expanded database of fusion genes Nucleic acids research, 2020, v.48 no.D1, D817-D824
  SCIE Scopus dColl.
• Earlier-Phased Cancer Immunity Cycle Strongly Influences Cancer Immunity in Operable Never-Smoker Lung Adenocarcinoma iScience, 2020, v.23 no.8, 101386
  Scopus dColl.
• Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer CELL DEATH AND DIFFERENTIATION, 2020, v.27 no.11, 3004-3020
  SCIE Scopus dColl.
• Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling REDOX BIOLOGY, 2020, v.29, UNSP 101391
  SCIE Scopus dColl.
• NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics NUCLEIC ACIDS RESEARCH, 2020 , 10753-10767
  SCIE Scopus dColl.
• PDX models of human lung squamous cell carcinoma: Consideration of factors in preclinical and co-clinical applications Journal of Translational Medicine, 2020, v.18 no.1, 307
  SCIE Scopus dColl.
• Validity of patient-derived xenograft mouse models for lung cancer based on exome sequencing data Genomics and Informatics, 2020, v.18 no.1, e3
  Scopus dColl.
• An Integrative Data Mining and Omics-Based Translational Model for the Identification and Validation of Oncogenic Biomarkers of Pancreatic Cancer CANCERS, 2019, v.11 no.2, 155
  SCIE Scopus dColl.
• CaPSSA: visual evaluation of cancer biomarker genes for patient stratification and survival analysis using mutation and expression data BIOINFORMATICS, 2019, v.35 no.24, 5341-5343
  SCIE Scopus dColl.
• FusionScan: accurate prediction of fusion genes from RNA-Seq data Genomics & Informatics, 2019, v.17 no.3, e26
  KCI dColl.
• Fusionscan: Accurate prediction of fusion genes from RNA-seq data Genomics and Informatics, 2019, v.17 no.3, e26
  Scopus dColl.
• Human cytomegalovirus induces and exploits Roquin to counteract the IRF1-mediated antiviral state PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, v.116 no.37, 18619-18628
  SCIE Scopus dColl.
• Identification of tumor suppressor miRNAs by integrative miRNA and mRNA sequencing of matched tumor-normal samples in lung adenocarcinoma MOLECULAR ONCOLOGY, 2019, v.13 no.6, 1356-1368
  SCIE Scopus dColl.
• Proteogenomic Characterization of Human Early-Onset Gastric Cancer Cancer Cell, 2019, v.35 no.1, 111-1.24E12
  SCIE Scopus dColl.
• An integrated clinical and genomic information system for cancer precision medicine BMC MEDICAL GENOMICS, 2018, v.11
  SCIE Scopus dColl.
• GEMiCCL: mining genotype and expression data of cancer cell lines with elaborate visualization DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2018, v.
  SCIE Scopus dColl.
• Integrative Profiling of Alternative Splicing Induced by U2AF1 S34F Mutation in Lung Adenocarcinoma Reveals a Mechanistic Link to Mitotic Stress MOLECULES AND CELLS, 2018, v.41 no.8, 733-741
  SCIE Scopus KCI dColl.
• Isolation and Functional Examination of the Long Non-Coding RNA Redrum Molecules and cells, 2018, v.41 no.2, 134-139
  Scopus dColl.
• Rpd3L HDAC links H3K4me3 to transcriptional repression memory NUCLEIC ACIDS RESEARCH, 2018, v.46 no.16, 8261-8274
  SCIE Scopus dColl.
• Silencing of peroxiredoxin II by promoter methylation is necessary for the survival and migration of gastric cancer cells Experimental & molecular medicine, 2018, v.50 no.2, e443
  SCIE Scopus KCI dColl.
• Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, v.50, 99
  SCIE Scopus KCI dColl.
• Characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic data SCIENTIFIC REPORTS, 2017, v.7
  SCIE Scopus dColl.
• ChimerDB 3.0: an enhanced database for fusion genes from cancer transcriptome and literature data mining NUCLEIC ACIDS RESEARCH, 2017, v.45 no.D1, D784-D789
  SCIE Scopus dColl.
• Integrative analysis of DNA methylation and mRNA expression during differentiation of umbilical cord blood derived mononuclear cells to endothelial cells Gene, 2017, v.635, 48-60
  SCIE Scopus dColl.
• Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells Nature Communications, 2017, v.8 no.1
  SCIE Scopus dColl.
• Korean Variant Archive (KOVA): A reference database of genetic variations in the Korean population Scientific Reports, 2017, v.7 no.1
  SCIE Scopus dColl.
• Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma HAEMATOLOGICA, 2016, v.101 no.6, 757-763
  SCIE Scopus dColl.
• MONGKIE: an integrated tool for network analysis and visualization for multi-omics data BIOLOGY DIRECT, 2016, v.11
  SCIE Scopus dColl.
• Programming of Plant Leaf Senescence with Temporal and Inter-Organellar Coordination of Transcriptome in Arabidopsis PLANT PHYSIOLOGY, 2016, v.171 no.1, 452-467
  SCIE Scopus dColl.
• Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecology PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, v.113 no.50, 14283-14288
  SCIE Scopus dColl.
• A highly recurrent novel missense mutation in CD28 among angioimmunoblastic T-cell lymphoma patients HAEMATOLOGICA, 2015, v.100 no.12, E505-E507
  SCIE Scopus dColl.
• Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer Oncotarget, 2015, v.6 no.28, 25368-25380
  SCIE Scopus dColl.
• Cytosolic Hsp60 orchestrates the survival and inflammatory responses of vascular smooth muscle cells in injured aortic vessels Cardiovascular Research, 2015, v.106 no.3, 498-508
  SCIE Scopus dColl.
• EMSAR: estimation of transcript abundance from RNA-seq data by mappability-based segmentation and reclustering BMC BIOINFORMATICS, 2015, v.16
  SCIE Scopus dColl.
• Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak(-/-) Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure PLOS ONE, 2015, v.10 no.10
  SCIE Scopus dColl.
• VAMP2-NRG1 Fusion Gene is a Novel Oncogenic Driver of Non-Small-Cell Lung Adenocarcinoma JOURNAL OF THORACIC ONCOLOGY, 2015, v.10 no.7, 1107-1111
  SCIE Scopus dColl.
• VAMP2-NRG1 fusion gene is a novel oncogenic driver of non-small cell lung adenocarcinoma CANCER RESEARCH, 2015, v.75
  SCIE Scopus dColl.
• miRseqViewer: multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing data BIOINFORMATICS, 2015, v.31 no.4, 596-598
  SCIE Scopus dColl.
• 2-Cys peroxiredoxins: Emerging hubs determining redox dependency of mammalian signaling networks International Journal of Cell Biology, 2014, v. 2014
  Scopus dColl.
• A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma Nature Genetics, 2014, v.46 no.4, 371-375
  SCIE Scopus dColl.
• Compact variant-rich customized sequence database and a fast and sensitive database search for efficient proteogenomic analyses Proteomics, 2014, v.14 no.23-24, 2742-2749
  SCIE Scopus dColl.
• GEPdb: a database for investigating the ternary association of genotype, gene expression and phenotype BIOINFORMATICS, 2014, v.30 no.17, 2540-2542
  SCIE Scopus dColl.
• GsGator: An integrated web platform for cross-species gene set analysis BMC Bioinformatics, 2014, v.15 no.1
  SCIE Scopus dColl.
• IncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs BIOINFORMATICS, 2014, v.30 no.17, 2480-2485
  SCIE Scopus dColl.
• Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, v.111 no.7, 2794-2799
  SCIE Scopus dColl.
• [학술지논문] DRSPRING: Graph convolutional network (GCN)-Based drug synergy prediction utilizing drug-induced gene expression profile COMPUTERS IN BIOLOGY AND MEDICINE, 2024, v.174 no.1 , 1-10
  SCIE
• [학술지논문] Dissecting transcriptome signals of anti-PD-1 response in lung adenocarcinoma SCIENTIFIC REPORTS, 2024, v.14 no.1 , 1-11
  SCIE
• [학술지논문] Glyoxalase 1: Emerging biomarker and therapeutic target in cervical cancer progression PLOS ONE, 2024, v.19 no.6 , 1-14
  SCIE
• [학술지논문] Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells SCIENTIFIC REPORTS, 2023, v.13 no.2404 , 1-14
  SCIE
• [학술지논문] Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord-Like Organoid (pSCO) with Dorsoventral Organization ADVANCED SCIENCE, 2023, v.10 no.2301787 , 1-18
  SCIE
• [학술지논문] A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population EXPERIMENTAL AND MOLECULAR MEDICINE, 2022, v.54 no.11 , 1862-1871
  SCI
• [학술지논문] Comprehensive Analysis of Alternative Splicing in Gastric Cancer Identifies Epithelial-Mesenchymal Transition Subtypes Associated with Survival CANCER RESEARCH, 2022, v.82 no.4 , 543-555
  SCI
• [학술지논문] Fluid Shear Stress Regulates the Landscape of microRNAs in Endothelial Cell-Derived Small Extracellular Vesicles and Modulates the Function of Endothelial Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, v.23 no.3 , 1314-1314
  SCIE
• [학술지논문] Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-Kappa B survival machinery in cancer cells REDOX BIOLOGY, 2022, v.51 no.102293 , 1-14
  SCIE
• [학술지논문] Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells ONCOIMMUNOLOGY, 2022, v.11 no.1 , 2015170-2015170
  SCIE
• [학술지논문] Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ Layers STEM CELL REVIEWS AND REPORTS, 2022, v.18 no.3 , 1181-1192
  SCIE
• [학술지논문] Production of human spinal-cord organoids recapitulating neural-tube morphogenesis NATURE BIOMEDICAL ENGINEERING, 2022, v.6 no.4 , 435-+
  SCIE
• [학술지논문] Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing Genomics and Informatics, 2021, v.19 no.1 , 2-2
  Scopus
• [학술지논문] FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress CELL DEATH & DISEASE, 2021, v.12 no.4 , 407-407
  SCIE
• [학술지논문] Genome-scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib-resistant lung cancer Molecular Oncology, 2021, v.15 no.2 , 487-502
  SCIE
• [학술지논문] Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells NEOPLASIA, 2021, v.23 no.9 , 993-1001
  SCI
• [학술지논문] iCSDB: an integrated database of CRISPR screens NUCLEIC ACIDS RESEARCH, 2021, v.49 no.D1 , 956-961
  SCI
• [학술지논문] Angioimmunoblastic T-cell lymphoma-like lymphadenopathy in mice transgenic for human RHOA with p.Gly17Val mutation ONCOIMMUNOLOGY, 2020, v.9 no.1 , 1746553-1746553
  SCIE
• [학술지논문] Bioinformatics services for analyzing massive genomic datasets Genomics and Informatics, 2020, v.18 no.1 , 1-10
  Scopus
• [학술지논문] Characterization of TNNC1 as a Novel Tumor Suppressor of Lung Adenocarcinoma MOLECULES AND CELLS, 2020, v.43 no.7 , 619-631
  SCI
• [학술지논문] ChimerDB 4.0: an updated and expanded database of fusion genes NUCLEIC ACIDS RESEARCH, 2020, v.48 no.D1 , 817-824
  SCI
• [학술지논문] Earlier-Phased Cancer Immunity Cycle Strongly Influences Cancer Immunity in Operable Never-Smoker Lung Adenocarcinoma iScience, 2020, v.23 no.8 , 1-16
  SCIE
• [학술지논문] Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer CELL DEATH AND DIFFERENTIATION, 2020, v.27 no.11 , 3004-3020
  SCI
• [학술지논문] Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling REDOX BIOLOGY, 2020, v.29 no.0 , 101391-101391
  SCIE
• [학술지논문] NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics NUCLEIC ACIDS RESEARCH, 2020, v.48 no.19 , 10753-10767
  SCI
• [학술지논문] PDX models of human lung squamous cell carcinoma: consideration of factors in preclinical and co-clinical applications JOURNAL OF TRANSLATIONAL MEDICINE, 2020, v.18 no.1 , 1-13
  SCIE
• [학술지논문] Validity of patient-derived xenograft mouse models for lung cancer based on exome sequencing data Genomics and Informatics, 2020, v.18 no.1 , 1-8
  Scopus

Academic Background