연구실적

• Mitochondrial H2O2 Is a Central Mediator of Diclofenac-Induced Hepatocellular Injury Antioxidants, 2024, v.13 no.1, 17
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• N-terminal acetylation of Set1-COMPASS fine-tunes H3K4 methylation patterns Science Advances, 2024, v.10 no.28, adl6280
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• Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity Investigative ophthalmology & visual science, 2024, v.65 no.3, 30
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• Complexation of drug and hapten-conjugated aptamer with universal hapten antibody for pancreatic cancer treatment Journal of Controlled Release, 2023, v.360, 940-952
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• Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation Cardiovascular Research, 2023, v.119 no.5, 1265-1278
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• Pancreatic β-cell mitophagy as an adaptive response to metabolic stress and the underlying mechanism that involves lysosomal Ca2+ release Experimental and Molecular Medicine, 2023, v.55 no.9, 1922-1932
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• Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson–Gilford Progeria Syndrome Cells, 2023, v.12 no.9, 1232
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• Unbalanced Redox With Autophagy in Cardiovascular Disease Journal of Lipid and Atherosclerosis, 2023, v.12 no.2, 132-151
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• 2′–5′ oligoadenylate synthetase‑like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability Nature Communications, 2022, v.13 no.1, 6647
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• Peroxiredoxin 2 deletion impairs hippocampal-dependent memory via exacerbating transient ischemia-induced oxidative damage Brain Research Bulletin, 2022, v.184, 99-105
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• Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control Redox Biology, 2022, v.51, 102275
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• Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non- Alcoholic Fatty Liver Disease in Mice DIABETES & METABOLISM JOURNAL, 2022, v.46 no.6, 829-842
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• Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice Diabetes and Metabolism Journal, 2022, v.46 no.6, 829-842
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• Plasma Membrane Localization of CD36 Requires Vimentin Phosphorylation; A Mechanism by Which Macrophage Vimentin Promotes Atherosclerosis FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, v.9, 792717
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• Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia Nature Communications, 2022, v.13 no.1, 5461
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• The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke Redox Biology, 2022, v.54, 102347
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• miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1 Cell Death and Differentiation, 2022
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• Combined application of rapamycin and atorvastatin improves lipid metabolism in apolipoprotein E-deficient mice with chronic kidney disease BMB REPORTS, 2021, v.54 no.3, 170-175
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• ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1 EXPERIMENTAL AND MOLECULAR MEDICINE, 2021, v.53 no.11, 1769-1780
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• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) AUTOPHAGY, 2021, v.17 no.1, 1-382
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• Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway ELIFE, 2021, v.10, e65952
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• Peroxiredoxins as Potential Targets for Cardiovascular Disease ANTIOXIDANTS, 2021, v.10 no.8, 1244
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• The adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells Cell Death and Disease, 2021, v.12 no.4, 307
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• Vimentin Deficiency Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice DIABETES & METABOLISM JOURNAL, 2021, v.45 no.1, 97-
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• Anti-Inflammatory Actions of Soluble Ninjurin-1 Ameliorate Atherosclerosis Circulation, 2020 , 1736-1751
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• Autophagy induction promotes renal cyst growth in polycystic kidney disease EBioMedicine, 2020, v.60, 102986
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• CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b(-)CD103(+) DCs CELL REPORTS, 2020, v.30 no.12, 4124-
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• Characterization of human cardiac mesenchymal stromal cells and their extracellular vesicles comparing with human bone marrow derived mesenchymal stem cells BMB REPORTS, 2020, v.53 no.2, 118-123
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• Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm EXPERIMENTAL AND MOLECULAR MEDICINE, 2020, v.52 no.9, 1587-1601
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• Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction BMB REPORTS, 2020 , 652-657
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• Ninjurin1 deficiency aggravates colitis development by promoting M1 macrophage polarization and inducing microbial imbalance FASEB JOURNAL, 2020 , 8702-8720
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• Oxidized LDL induces vimentin secretion by macrophages and contributes to atherosclerotic inflammation JOURNAL OF MOLECULAR MEDICINE-JMM, 2020 , 973-983
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• SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis Redox Biology, 2020, v.37, 101760
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• The Autophagy Regulator p62 Controls PTEN-Dependent Ciliogenesis FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, v.8, 465
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• The Peroxisome Proliferator-Activated Receptor alpha- Agonist Gemfibrozil Promotes Defense Against Mycobacterium abscessus Infections CELLS, 2020, v.9 no.3, 648
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• Current pharmacotherapies for atherosclerotic cardiovascular diseases ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42 no.3, 206-223
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• Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress ANTIOXIDANTS & REDOX SIGNALING, 2019, v.31 no.18, 1339-1351
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• Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts EXPERIMENTAL AND MOLECULAR MEDICINE, 2019, v.51, 7
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• C1q/TNF-alpha-Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions CIRCULATION RESEARCH, 2018, v.123 no.5, E5-E19
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• Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo AUTOPHAGY, 2018, v.14 no.6, 1011-1027
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• Conventional Dendritic Cells Impair Recovery after Myocardial Infarction JOURNAL OF IMMUNOLOGY, 2018, v.201 no.6, 1784-1798
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• Impairment of PPAR alpha and the Fatty Acid Oxidation Pathway Aggravates Renal Fibrosis during Aging JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2018, v.29 no.4, 1223-1237
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• LJ-1888, a selective antagonist for the A(3) adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice BMB REPORTS, 2018, v.51 no.10, 520-525
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• N-alpha-acetyltransferase 10 (NAA10) in development: the role of NAA10 EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, v.50, 87
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• Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux AUTOPHAGY, 2018, v.14 no.1, 120-133
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• Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models CIRCULATION RESEARCH, 2018, v.123 no.10, 1127-1142
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• Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets CARDIOVASCULAR RESEARCH, 2017, v.113 no.11, 1307-1317
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• INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis Oncotarget, 2017, v.8 no.70, 115041-115053
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• Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, v.114 no.10, E1885-E1894
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• Negligible effect of eNOS palmitoylation on fatty acid regulation of contraction in ventricular myocytes from healthy and hypertensive rats PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2017, v.469 no.9, 1141-1149
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• PPAR-alpha Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism JOURNAL OF IMMUNOLOGY, 2017, v.198 no.8, 3283-3295
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• Peroxiredoxin I participates in the protection of reactive oxygen species-mediated cellular senescence BMB Reports, 2017, v.50 no.10, 528-533
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• The role of macrophage lipophagy in reverse cholesterol transport Endocrinology and Metabolism, 2017, v.32 no.1, 41-46
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• ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation NATURE COMMUNICATIONS, 2016, v.7
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• Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice Molecular Neurobiology, 2016, v.54 no.9, 1-16
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• INCREASED MITOCHONDRIAL ROS ACCELERATE ATHEROSCLEROSIS IN MITOCHONDRIAL CATALYTIC ENZYME 3 DEFICIENT MICE ATHEROSCLEROSIS, 2016, v.252, E220-E220
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• Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells Cell Metabolism, 2016, v.23 no.5, 852-866
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• KCa3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stress Aging Cell, 2016, v.15 no.5
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• Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states SCIENTIFIC REPORTS, 2016, v.6
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• Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling ONCOTARGET, 2016, v.7 no.20, 29592-29604
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• PEROXIREDOXIN 1 HAVE PROTECTIVE ROLE IN THE VASCULAR DISEASE BY REGULATING MACROPHAGES ATHEROSCLEROSIS, 2016, v.252, E226-E226
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• PEROXIREDOXIN1 PROTECTS MACROPHAGES FROM IMPAIRED LIPOPHAGIC FLUX BY OXIDATIVE STRESS IN ATHEROSCLEROSIS CARDIOLOGY, 2016, v.134, 398-398
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• Role of muscular eNOS in skeletal arteries: endothelium-independent hypoxic vasoconstriction of the femoral artery is impaired in eNOS-deficient mice AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, v.311 no.3, C508-C517
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• Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation Scientific Reports, 2016, v.6
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• The Roles of CD137 Signaling in Atherosclerosis KOREAN CIRCULATION JOURNAL, 2016, v.46 no.6, 753-761
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• 토끼에서 ACAT 억제에 의한 3,4-다이하이드록시 하이드로시나믹산의 동맥경화 완화 효과 대한임상검사과학회지, 2016, v.48 no.4, 280
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• Extract of Rhus verniciflua stokes protects the diet-induced hyperlipidemia in mice Archives of Pharmacal Research, 2015, v.38 no.11, 2049-2058
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• Regulation of IGFBP-2 expression during fasting BIOCHEMICAL JOURNAL, 2015, v.467, 453-460
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• Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A Cell Death and Disease, 2014, v.5 no.10
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• CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice FASEB JOURNAL, 2014, v.28 no.11, 4779-4791
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• Developmental endothelial locus-1 inhibits MIF production through suppression of NF-kappa B in macrophages INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, v.33 no.4, 919-924
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• Hypoxia-Induced Endothelial Progenitor Cell Function Is Blunted in Angiotensinogen Knockout Mice MOLECULES AND CELLS, 2014, v.37 no.6, 487-496
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• Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, v.111 no.26, E2731-E2740
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• NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2 NATURE COMMUNICATIONS, 2014, v.5
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• Ninjurin1 Deficiency Attenuates Susceptibility of Experimental Autoimmune Encephalomyelitis in Mice JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, v.289 no.6, 3328-3338
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• Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics Journal of Biological Chemistry, 2014, v.289 no.32, 21926-21936
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• Reactive Oxygen Species Play a Critical Role in Collagen-Induced Platelet Activation via SHP-2 Oxidation ANTIOXIDANTS & REDOX SIGNALING, 2014, v.20 no.16, 2528-2540
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• Retnla Overexpression Attenuates Allergic Inflammation of the Airway PLOS ONE, 2014, v.9 no.11
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• The adipokine ​Retnla modulates ​cholesterol homeostasis in hyperlipidemic mice Nature Communications, 2014, v.5, Article number:4410
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• Tripartite Motif-Containing Protein 30 Modulates TCR-Activated Proliferation and Effector Functions in CD4(+) T Cells PLOS ONE, 2014, v.9 no.4, Article ID e95805
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• Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, v.449 no.2, 202-207
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