이상혁 교수는 생명과학전공/바이오정보학협동과정 소속 교수로 생명정보학 및 유전체학 분야의 연구를 수행하고 있다. 한국생물정보시스템생물학회 회장, 국가생명연구자원정보센터의 센터장, 국가과학기술위원회 생명보건전문위원 등을 역임하였으며, <Nature Genetics>를 비롯한 최상급 전문 학술지에 다수의 논문을 발표하였다. 현재 이화시스템생물학연구소 소장, 바이오정보학협동과정 주임교수이며, 국제염기서열공유자문위원으로 활동하고 있다.
Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord-Like Organoid (pSCO) with Dorsoventral OrganizationAdvanced Science, 2023, v.10 no.20, 2301787
A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian populationExperimental and Molecular Medicine, 2022, v.54, 1-10
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Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cellsONCOIMMUNOLOGY, 2022, v.11 no.1, 2015170
Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ LayersStem Cell Reviews and Reports, 2022, v.18 no.3, 1181-1192
Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencingGenomics and Informatics, 2021, v.19 no.1, e2
FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stressCell Death and Disease, 2021, v.12 no.4, 407
Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cellsNEOPLASIA, 2021, v.23 no.9, 993-1001
Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancerCELL DEATH AND DIFFERENTIATION, 2020, v.27 no.11, 3004-3020
Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signalingREDOX BIOLOGY, 2020, v.29, UNSP 101391
PDX models of human lung squamous cell carcinoma: Consideration of factors in preclinical and co-clinical applicationsJournal of Translational Medicine, 2020, v.18 no.1, 307
An Integrative Data Mining and Omics-Based Translational Model for the Identification and Validation of Oncogenic Biomarkers of Pancreatic CancerCANCERS, 2019, v.11 no.2, 155
CaPSSA: visual evaluation of cancer biomarker genes for patient stratification and survival analysis using mutation and expression dataBIOINFORMATICS, 2019, v.35 no.24, 5341-5343
Human cytomegalovirus induces and exploits Roquin to counteract the IRF1-mediated antiviral statePROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, v.116 no.37, 18619-18628
Identification of tumor suppressor miRNAs by integrative miRNA and mRNA sequencing of matched tumor-normal samples in lung adenocarcinomaMOLECULAR ONCOLOGY, 2019, v.13 no.6, 1356-1368
GEMiCCL: mining genotype and expression data of cancer cell lines with elaborate visualizationDATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2018, v.
Integrative Profiling of Alternative Splicing Induced by U2AF1 S34F Mutation in Lung Adenocarcinoma Reveals a Mechanistic Link to Mitotic StressMOLECULES AND CELLS, 2018, v.41 no.8, 733-741
Silencing of peroxiredoxin II by promoter methylation is necessary for the survival and migration of gastric cancer cellsExperimental & molecular medicine, 2018, v.50 no.2, e443
Characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic dataSCIENTIFIC REPORTS, 2017, v.7
ChimerDB 3.0: an enhanced database for fusion genes from cancer transcriptome and literature data miningNUCLEIC ACIDS RESEARCH, 2017, v.45 no.D1, D784-D789
Integrative analysis of DNA methylation and mRNA expression during differentiation of umbilical cord blood derived mononuclear cells to endothelial cellsGene, 2017, v.635, 48-60
Programming of Plant Leaf Senescence with Temporal and Inter-Organellar Coordination of Transcriptome in ArabidopsisPLANT PHYSIOLOGY, 2016, v.171 no.1, 452-467
Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecologyPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, v.113 no.50, 14283-14288
Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak(-/-) Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy ExpenditurePLOS ONE, 2015, v.10 no.10
miRseqViewer: multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing dataBIOINFORMATICS, 2015, v.31 no.4, 596-598
Compact variant-rich customized sequence database and a fast and sensitive database search for efficient proteogenomic analysesProteomics, 2014, v.14 no.23-24, 2742-2749
Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous systemPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, v.111 no.7, 2794-2799
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[학술지논문] A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population
EXPERIMENTAL AND MOLECULAR MEDICINE, 2022, v.54
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[학술지논문] Comprehensive Analysis of Alternative Splicing in Gastric Cancer Identifies Epithelial-Mesenchymal Transition Subtypes Associated with Survival
CANCER RESEARCH, 2022, v.82
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SCI
[학술지논문] Fluid Shear Stress Regulates the Landscape of microRNAs in Endothelial Cell-Derived Small Extracellular Vesicles and Modulates the Function of Endothelial Cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, v.23
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SCIE
[학술지논문] Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-Kappa B survival machinery in cancer cells
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[학술지논문] Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells
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[학술지논문] Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ Layers
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[학술지논문] Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing
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[학술지논문] FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress
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[학술지논문] Genome-scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib-resistant lung cancer
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[학술지논문] Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells
NEOPLASIA, 2021, v.23
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[학술지논문] iCSDB: an integrated database of CRISPR screens
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ONCOIMMUNOLOGY, 2020, v.9
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[학술지논문] Bioinformatics services for analyzing massive genomic datasets
Genomics and Informatics, 2020, v.18
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[학술지논문] Characterization of TNNC1 as a Novel Tumor Suppressor of Lung Adenocarcinoma
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no.D1
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SCI
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no.8
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SCIE
[학술지논문] Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer
CELL DEATH AND DIFFERENTIATION, 2020, v.27
no.11
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SCI
[학술지논문] Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling
REDOX BIOLOGY, 2020, v.29
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SCIE
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BIOINFORMATICS, 2019, v.35
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[학술지논문] FusionScan: accurate prediction of fusion genes from RNA-Seq data
Genomics & Informatics, 2019, v.17
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[학술지논문] Human cytomegalovirus induces and exploits Roquin to counteract the IRF1-mediated antiviral state
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, v.116
no.37
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SCI
[학술지논문] Identification of tumor suppressor miRNAs by integrative miRNA and mRNA sequencing of matched tumor-normal samples in lung adenocarcinoma
Molecular Oncology, 2019, v.13
no.6
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SCIE
[학술지논문] Proteogenomic Characterization of Human Early-Onset Gastric Cancer
CANCER CELL, 2019, v.35
no.1
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