Goo Taeg Oh Professor

Life Sciences/Life Sciences

오구택 프로필 사진
Developmental Genetics, Molecular Medicine, Cardiovascular Disease/ 
Distinguished Professor/
Korean Society of Biochemistry and Molecular Biology (BMB Reports) Editorial Board, 2008-Present/
National Research Foundation of Korea, Review Board, 2010-Present/
Director, National Creative Initiatives Center for Immune and Vascular Cell Network, National Research Foundation of Korea, 2012-2021/
Published over 136 papers(~2014) in Immunity,  Nat Immunol., Circulation, Circulation Research, Nature Communications and other journals
  • Science Building C #305
  • 02-3277-4128
  • Office hours
    • 월요일 오후 2시
Research Record
  • Complexation of drug and hapten-conjugated aptamer with universal hapten antibody for pancreatic cancer treatment Journal of Controlled Release, 2023, v.360, 940-952
    SCIE Scopus dColl.
  • Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation Cardiovascular Research, 2023, v.119 no.5, 1265-1278
    SCIE Scopus dColl.
  • Pancreatic β-cell mitophagy as an adaptive response to metabolic stress and the underlying mechanism that involves lysosomal Ca2+ release Experimental and Molecular Medicine, 2023, v.55 no.9, 1922-1932
    SCIE Scopus KCI dColl.
  • Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson–Gilford Progeria Syndrome Cells, 2023, v.12 no.9, 1232
    SCIE Scopus dColl.
  • Unbalanced Redox With Autophagy in Cardiovascular Disease Journal of Lipid and Atherosclerosis, 2023, v.12 no.2, 132-151
    Scopus dColl.
  • 2′–5′ oligoadenylate synthetase‑like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability Nature Communications, 2022, v.13 no.1, 6647
    SCIE Scopus dColl.
  • Peroxiredoxin 2 deletion impairs hippocampal-dependent memory via exacerbating transient ischemia-induced oxidative damage Brain Research Bulletin, 2022, v.184, 99-105
    SCIE Scopus dColl.
  • Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control Redox Biology, 2022, v.51, 102275
    SCIE Scopus dColl.
  • Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non- Alcoholic Fatty Liver Disease in Mice DIABETES & METABOLISM JOURNAL, 2022, v.46 no.6, 829-842
    SCIE Scopus KCI dColl.
  • Plasma Membrane Localization of CD36 Requires Vimentin Phosphorylation; A Mechanism by Which Macrophage Vimentin Promotes Atherosclerosis FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, v.9, 792717
    SCIE Scopus dColl.
  • Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia Nature Communications, 2022, v.13 no.1, 5461
    SCIE Scopus dColl.
  • The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke Redox Biology, 2022, v.54, 102347
    SCIE Scopus dColl.
  • miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1 Cell Death and Differentiation, 2022
    SCIE Scopus dColl.
  • Combined application of rapamycin and atorvastatin improves lipid metabolism in apolipoprotein E-deficient mice with chronic kidney disease BMB REPORTS, 2021, v.54 no.3, 170-175
    SCIE Scopus KCI dColl.
  • ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1 EXPERIMENTAL AND MOLECULAR MEDICINE, 2021, v.53 no.11, 1769-1780
    SCIE Scopus KCI dColl.
  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) AUTOPHAGY, 2021, v.17 no.1, 1-382
    SCIE Scopus dColl.
  • Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway ELIFE, 2021, v.10, e65952
    SCIE Scopus dColl.
  • Peroxiredoxins as Potential Targets for Cardiovascular Disease ANTIOXIDANTS, 2021, v.10 no.8, 1244
    SCIE Scopus dColl.
  • The adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells Cell Death and Disease, 2021, v.12 no.4, 307
    SCIE Scopus dColl.
  • Vimentin Deficiency Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice DIABETES & METABOLISM JOURNAL, 2021, v.45 no.1, 97-
    SCIE Scopus KCI dColl.
  • Anti-Inflammatory Actions of Soluble Ninjurin-1 Ameliorate Atherosclerosis Circulation, 2020 , 1736-1751
    SCIE Scopus dColl.
  • Autophagy induction promotes renal cyst growth in polycystic kidney disease EBioMedicine, 2020, v.60, 102986
    SCIE Scopus dColl.
  • CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b(-)CD103(+) DCs CELL REPORTS, 2020, v.30 no.12, 4124-
    SCIE Scopus dColl.
  • Characterization of human cardiac mesenchymal stromal cells and their extracellular vesicles comparing with human bone marrow derived mesenchymal stem cells BMB REPORTS, 2020, v.53 no.2, 118-123
    SCIE Scopus KCI dColl.
  • Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm EXPERIMENTAL AND MOLECULAR MEDICINE, 2020, v.52 no.9, 1587-1601
    SCIE Scopus KCI dColl.
  • Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction BMB REPORTS, 2020 , 652-657
    SCIE Scopus KCI dColl.
  • Ninjurin1 deficiency aggravates colitis development by promoting M1 macrophage polarization and inducing microbial imbalance FASEB JOURNAL, 2020 , 8702-8720
    SCIE Scopus dColl.
  • Oxidized LDL induces vimentin secretion by macrophages and contributes to atherosclerotic inflammation JOURNAL OF MOLECULAR MEDICINE-JMM, 2020 , 973-983
    SCIE Scopus dColl.
  • SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis Redox Biology, 2020, v.37, 101760
    SCIE Scopus dColl.
  • The Autophagy Regulator p62 Controls PTEN-Dependent Ciliogenesis FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, v.8, 465
    SCIE Scopus dColl.
  • The Peroxisome Proliferator-Activated Receptor alpha- Agonist Gemfibrozil Promotes Defense Against Mycobacterium abscessus Infections CELLS, 2020, v.9 no.3, 648
    SCIE Scopus dColl.
  • Current pharmacotherapies for atherosclerotic cardiovascular diseases ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42 no.3, 206-223
    SCIE Scopus KCI dColl.
  • Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress ANTIOXIDANTS & REDOX SIGNALING, 2019, v.31 no.18, 1339-1351
    SCIE Scopus dColl.
  • Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts EXPERIMENTAL AND MOLECULAR MEDICINE, 2019, v.51, 7
    SCIE Scopus KCI dColl.
  • C1q/TNF-alpha-Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions CIRCULATION RESEARCH, 2018, v.123 no.5, E5-E19
    SCIE Scopus dColl.
  • Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo AUTOPHAGY, 2018, v.14 no.6, 1011-1027
    SCIE Scopus dColl.
  • Conventional Dendritic Cells Impair Recovery after Myocardial Infarction JOURNAL OF IMMUNOLOGY, 2018, v.201 no.6, 1784-1798
    SCIE Scopus dColl.
  • Impairment of PPAR alpha and the Fatty Acid Oxidation Pathway Aggravates Renal Fibrosis during Aging JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2018, v.29 no.4, 1223-1237
    SCIE Scopus dColl.
  • LJ-1888, a selective antagonist for the A(3) adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice BMB REPORTS, 2018, v.51 no.10, 520-525
    SCIE Scopus KCI dColl.
  • N-alpha-acetyltransferase 10 (NAA10) in development: the role of NAA10 EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, v.50, 87
    SCIE Scopus KCI dColl.
  • Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux AUTOPHAGY, 2018, v.14 no.1, 120-133
    SCIE Scopus dColl.
  • Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models CIRCULATION RESEARCH, 2018, v.123 no.10, 1127-1142
    SCIE Scopus dColl.
  • Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets CARDIOVASCULAR RESEARCH, 2017, v.113 no.11, 1307-1317
    SCIE Scopus dColl.
  • INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis Oncotarget, 2017, v.8 no.70, 115041-115053
    SCIE Scopus dColl.
  • Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, v.114 no.10, E1885-E1894
    SCIE Scopus dColl.
  • Negligible effect of eNOS palmitoylation on fatty acid regulation of contraction in ventricular myocytes from healthy and hypertensive rats PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2017, v.469 no.9, 1141-1149
    SCIE Scopus dColl.
  • PPAR-alpha Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism JOURNAL OF IMMUNOLOGY, 2017, v.198 no.8, 3283-3295
    SCIE Scopus dColl.
  • Peroxiredoxin I participates in the protection of reactive oxygen species-mediated cellular senescence BMB Reports, 2017, v.50 no.10, 528-533
    SCIE Scopus KCI dColl.
  • The role of macrophage lipophagy in reverse cholesterol transport Endocrinology and Metabolism, 2017, v.32 no.1, 41-46
    Scopus KCI dColl.
  • ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation NATURE COMMUNICATIONS, 2016, v.7
    SCIE Scopus dColl.
  • Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice Molecular Neurobiology, 2016, v.54 no.9, 1-16
    SCIE Scopus dColl.
  • INCREASED MITOCHONDRIAL ROS ACCELERATE ATHEROSCLEROSIS IN MITOCHONDRIAL CATALYTIC ENZYME 3 DEFICIENT MICE ATHEROSCLEROSIS, 2016, v.252, E220-E220
    SCIE Scopus dColl.
  • Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells Cell Metabolism, 2016, v.23 no.5, 852-866
    SCIE Scopus dColl.
  • KCa3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stress Aging Cell, 2016, v.15 no.5
    SCIE Scopus dColl.
  • Metformin stimulates IGFBP-2 gene expression through PPARalpha in diabetic states SCIENTIFIC REPORTS, 2016, v.6
    SCIE Scopus dColl.
  • Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling ONCOTARGET, 2016, v.7 no.20, 29592-29604
    SCIE Scopus dColl.
  • PEROXIREDOXIN 1 HAVE PROTECTIVE ROLE IN THE VASCULAR DISEASE BY REGULATING MACROPHAGES ATHEROSCLEROSIS, 2016, v.252, E226-E226
    SCIE Scopus dColl.
  • PEROXIREDOXIN1 PROTECTS MACROPHAGES FROM IMPAIRED LIPOPHAGIC FLUX BY OXIDATIVE STRESS IN ATHEROSCLEROSIS CARDIOLOGY, 2016, v.134, 398-398
    SCIE Scopus dColl.
  • Role of muscular eNOS in skeletal arteries: endothelium-independent hypoxic vasoconstriction of the femoral artery is impaired in eNOS-deficient mice AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, v.311 no.3, C508-C517
    SCIE Scopus dColl.
  • Sirt6 cooperates with Blimp1 to positively regulate osteoclast differentiation Scientific Reports, 2016, v.6
    SCIE Scopus dColl.
  • The Roles of CD137 Signaling in Atherosclerosis KOREAN CIRCULATION JOURNAL, 2016, v.46 no.6, 753-761
    SCIE Scopus KCI dColl.
  • 토끼에서 ACAT 억제에 의한 3,4-다이하이드록시 하이드로시나믹산의 동맥경화 완화 효과 대한임상검사과학회지, 2016, v.48 no.4, 280
    KCI후보 dColl.
  • Extract of Rhus verniciflua stokes protects the diet-induced hyperlipidemia in mice Archives of Pharmacal Research, 2015, v.38 no.11, 2049-2058
    SCIE KCI Scopus dColl.
  • Regulation of IGFBP-2 expression during fasting BIOCHEMICAL JOURNAL, 2015, v.467, 453-460
    SCIE Scopus dColl.
  • Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A Cell Death and Disease, 2014, v.5 no.10
    SCIE Scopus dColl.
  • CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice FASEB JOURNAL, 2014, v.28 no.11, 4779-4791
    SCIE Scopus dColl.
  • Developmental endothelial locus-1 inhibits MIF production through suppression of NF-kappa B in macrophages INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, v.33 no.4, 919-924
    SCIE Scopus dColl.
  • Hypoxia-Induced Endothelial Progenitor Cell Function Is Blunted in Angiotensinogen Knockout Mice MOLECULES AND CELLS, 2014, v.37 no.6, 487-496
    SCIE KCI Scopus dColl.
  • Inhibition of Ninjurin 1 restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, v.111 no.26, E2731-E2740
    SCIE Scopus dColl.
  • NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2 NATURE COMMUNICATIONS, 2014, v.5
    SCIE dColl.
  • Ninjurin1 Deficiency Attenuates Susceptibility of Experimental Autoimmune Encephalomyelitis in Mice JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, v.289 no.6, 3328-3338
    SCIE Scopus dColl.
  • Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics Journal of Biological Chemistry, 2014, v.289 no.32, 21926-21936
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  • Reactive Oxygen Species Play a Critical Role in Collagen-Induced Platelet Activation via SHP-2 Oxidation ANTIOXIDANTS & REDOX SIGNALING, 2014, v.20 no.16, 2528-2540
    SCIE Scopus dColl.
  • Retnla Overexpression Attenuates Allergic Inflammation of the Airway PLOS ONE, 2014, v.9 no.11
    SCIE Scopus dColl.
  • The adipokine ​Retnla modulates ​cholesterol homeostasis in hyperlipidemic mice Nature Communications, 2014, v.5, Article number:4410
    SCIE Scopus dColl.
  • Tripartite Motif-Containing Protein 30 Modulates TCR-Activated Proliferation and Effector Functions in CD4(+) T Cells PLOS ONE, 2014, v.9 no.4, Article ID e95805
    SCIE Scopus dColl.
  • Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, v.449 no.2, 202-207
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Courses
  • 2024-1st

    • Developmental Biology

      • Subject No 20598Class No 01
      • 3Year ( 3Credit , 3Hour) Wed 6~6 (POSCO365) , Fri 4~4 (POSCO365)
    • Special Topics in Developmental Genetics Ⅰ

      • Subject No G16954Class No 01
      • Year ( 3Credit , 3Hour) Wed 2~3 (SCI-C418)
  • 2023-2nd

  • 2023-1st

  • 2021-2nd

    • Molecular Medical Science

      • Subject No 36336Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 5~5 , Thu 6~6
    • Animal Physiology II

      • Subject No 38209Class No 01
      • 2Year ( 3Credit , 3Hour) Mon 3~3 (POSCO452) , Wed 2~2 (POSCO452)
    • Special Topics in Developmental Genetics Ⅱ

      • Subject No G16955Class No 01
      • Year ( 3Credit , 3Hour) Mon 5~6 (SCI-C)
  • 2021-1st

    • First-Year Seminar

      • Subject No 10851Class No 12
      • 1Year ( 1Credit Mon 7~7 (SCI-C303)
    • Developmental Biology

      • Subject No 20598Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 5~5 , Thu 6~6
    • Experiments in Life Sciences III

      • Subject No 35313Class No 01
      • 3Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA205)
    • Experiments in Life Sciences III

      • Subject No 35313Class No 02
      • 3Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA205)
    • Special Topics in Developmental Genetics Ⅰ

      • Subject No G16954Class No 01
      • Year ( 3Credit , 3Hour) Wed 2~3
Academic Background

Seoul Nat'l Univ. 수의학박사(수의학)