Kong Joo Lee Professor Emeritus
Kong-Joo Lee is a first generation of woman scientists in Korea. She got BA in Ewha, MS in KAIST and Ph.D in Stanford University. Her research field is the study of cancer metastasis, angiogenesis, stress response combining with proteomics and systems biology. She published over 100 papers in esteemed journals. Based on her carrier, she was editorial board member in Mol Cell Proteomics and she contribute the promotion of women scientists in Koreas as a president of KWSE and worldwide as a president of INWES (International Network of Women Engineers and Scientists).
Research Record
- The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation JOURNAL OF MOLECULAR CELL BIOLOGY, 2022, v.14 no.6, mjac037
- Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation EXPERIMENTAL AND MOLECULAR MEDICINE, 2021, v.53 no.3, 346-357
- Nm23-H1 activator phenylbutenoid dimer exerts cytotoxic effects on metastatic breast cancer cells by inducing mitochondrial dysfunction only under glucose starvation SCIENTIFIC REPORTS, 2021, v.11 no.1, 23549
- Stepwise oxidations play key roles in the structural and functional regulations of DJ-1 BIOCHEMICAL JOURNAL, 2021, v.478 no.19, 3505-3525
- Cataract-Associated New Mutants S175G/H181Q of beta Beta 2-Crystallin and P24S/S31G of gamma D-Crystallin Are Involved in Protein Aggregation by Structural Changes INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21 no.18, 6504
- Activity-Regulated Cytoskeleton-Associated Protein (Arc/Arg3.1) is Transiently Expressed after Heat Shock Stress and Suppresses Heat Shock Factor 1 Scientific Reports, 2019, v.9 no.1, 2592
- Network-based integrated analysis of omics data reveal novel players ofTGF-beta 1-induced EMT in human peritoneal mesothelial cells SCIENTIFIC REPORTS, 2019, v.9, 1497
- deMix: Decoding Deuterated Distributions from Heterogeneous Protein States via HDX-MS Scientific Reports, 2019, v.9 no.1, 3176
- Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications MOLECULAR & CELLULAR PROTEOMICS, 2018, v.17 no.9, 1803-1823
- Small molecule activator of Nm23/NDPK as an inhibitor of metastasis SCIENTIFIC REPORTS, 2018, v.8
- Ubiquitin C-terminal hydrolase-L1 plays a key role in angiogenesis by regulating hydrogen peroxide generated by NADPH oxidase 4 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, v.495 no.1, 1567-1572
- Calcium Ion Induced Structural Changes Promote Dimerization of Secretagogin, Which is Required for Its Insulin Secretory Function Scientific Reports, 2017, v.7 no.1
- Heterogeneous nuclear ribonucleoprotein K inhibits heat shock-induced transcriptional activity of heat shock factor 1 JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, v.292 no.31, 12801-12812
- ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation NATURE COMMUNICATIONS, 2016, v.7
- Degradation of Redox-Sensitive Proteins including Peroxiredoxins and DJ-1 is Promoted by Oxidation-induced Conformational Changes and Ubiquitination SCIENTIFIC REPORTS, 2016, v.6
- Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus MOLECULAR AND CELLULAR BIOLOGY, 2016, v.36 no.7, 1136-1151
- Mechanistic elucidation guided by covalent inhibitors for the development of anti-diabetic PPARγ ligands Chemical Science, 2016, v.7 no.8, 5523-5529
- Secretagogin affects insulin secretion in pancreatic beta-cells by regulating actin dynamics and focal adhesion BIOCHEMICAL JOURNAL, 2016, v.473, 1791-1803
- Evidence for the Dimerization-Mediated Catalysis of Methionine Sulfoxide Reductase A from Clostridium oremlandii PLOS ONE, 2015, v.10 no.6
- Hydrogen-deuterium exchange mass spectrometry for determining protein structural changes in drug discovery Archives of Pharmacal Research, 2015, v.38 no.10, 1737-1745
- Mechanism of 1-Cys type methionine sulfoxide reductase Aregeneration by glutaredoxin Biochemical and Biophysical Research Communications, 2015
- Proteomic Analysis of INS-1 Rat Insulinoma Cells: ER Stress Effects and the Protective Role of Exenatide, a GLP-1 Receptor Agonist PLOS ONE, 2015, v.10 no.3
- ROSICS: CHEMISTRY AND PROTEOMICS OF CYSTEINE MODIFICATIONS IN REDOX BIOLOGY MASS SPECTROMETRY REVIEWS, 2015, v.34 no.2, 184-208
- Translationally Controlled Tumor Protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasis SCIENTIFIC REPORTS, 2015, v.5
- Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4 Oncotarget, 2015, v.6 no.18, 16287-16303
- N-terminal truncated UCH-L1 prevents Parkinson's disease associated damage PLoS ONE, 2014, v.9 no.6
- Sulfhydryl-Specific Probe for Monitoring Protein Redox Sensitivity ACS CHEMICAL BIOLOGY, 2014, v.9 no.12, 2883-2894
- [학술발표] Modifications Control Protein Stability and Biological Functions in Redox Sensitive Proteins International Conference of the Korean Society for Molecular and Cellular Biology, 대한민국, 2126-09-01 International Conference of the Korean Society for Molecular and Cellular Biology, 2126
Courses
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2023-1st
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Pharmaceutical Analysis Ⅰ 강의 계획서 상세보기
- Subject No 38930Class No 01
- 2Year ( 3Credit , 3Hour) Tue 3~3 (POSCO367) , Thu 5~5 (PHM-A400)
- Major Requisite
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Academic Background
Stanford University Ph.D.(화학)