Professor Sang-Jip Nam received his Ph.D. from Seoul National University. He worked on the development of new anti-cancer compounds and antibiotics from marine natural products at the Scripps Institution of Oceanography during his postdoctoral fellowship. Then he joined the Department of Chemistry and Nano Science, at Ewha Woman’s University in 2013. His research focused on the discovery of medicines from diverse natural sources. He has published many papers in top chemistry journals such as J. Am. Chem. Soc., Angew. Chem. Int. Ed. Engl., Nat. Chem. Biol., Org. Lett. etc.
Anithiactin D, a Phenylthiazole Natural Product from Mudflat-Derived Streptomyces sp., Suppresses Motility of Cancer CellsMarine Drugs, 2024, v.22 no.2, 88
Anti-Melanogenic Activity of Undecylprodigiosin, a Red Pigment Isolated from a Marine Streptomyces sp. SNA-077Biomolecules and Therapeutics, 2024, v.32 no.4, 492-498
Identification and characterization of a marine bacterium extract from Mameliella sp. M20D2D8 with antiviral effects against influenza A and B virusesArchives of Virology, 2024, v.169 no.3, 41
Methylanthranilate, a Food Fragrance Attenuates Skin Pigmentation through Downregulation of Melanogenic Enzymes by cAMP SuppressionBiomolecules and Therapeutics, 2024, v.32 no.2, 231-239
Safety assessment of Paeonia lactiflora root extract for a cosmetic ingredient employing the threshold of toxicological concern (TTC) approachRegulatory Toxicology and Pharmacology, 2024, v.149, 105620
Serratiomycins D1-D3, Antibacterial Cyclic Peptides from a Serratia sp. and Structure Revision of SerratiomycinJournal of Natural Products, 2024, v.87 no.5, 1330-1337
1′-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch signalingScientific Reports, 2023, v.13 no.1, 2811
4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functionsFood Science and Human Wellness, 2023, v.12 no.4, 1287-1299
Actinoquinazolinone, a New Quinazolinone Derivative from a Marine Bacterium Streptomyces sp. CNQ-617, Suppresses the Motility of Gastric Cancer CellsMarine Drugs, 2023, v.21 no.9, 489
Discovery and Biosynthesis of Cihunamides, Macrocyclic Antibacterial RiPPs with a Unique C−N Linkage Formed by CYP450 CatalysisAngewandte Chemie - International Edition, 2023, v.62 no.26, e202300998
Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-beta-Aggregation-Regulating Activity from a Marine Bacillus sp.MARINE DRUGS, 2023, v.21 no.2, 67
Libertellenone T, a Novel Compound Isolated from Endolichenic Fungus, Induces G2/M Phase Arrest, Apoptosis, and Autophagy by Activating the ROS/JNK Pathway in Colorectal Cancer CellsCANCERS, 2023, v.15 no.2, 489
Sadopeptins A and B, Sulfoxide- and Piperidone-Containing Cyclic Heptapeptides with Proteasome Inhibitory Activity from a Streptomyces sp.JOURNAL OF NATURAL PRODUCTS, 2023, v.86 no.3, 612-620
Safety assessment of Cnidium officinale rhizome extract in cosmetics using the Threshold of Toxicological Concern (TTC) approachRegulatory Toxicology and Pharmacology, 2023, v.142, 105433
Targeted and Logical Discovery of Piperazic Acid-Bearing Natural Products Based on Genomic and Spectroscopic SignaturesJOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, v.145 no.36, 19676-19690
Tsaokoic Acid: A New Bicyclic Nonene from the Fruits of Amomum tsao-ko with Acetylcholinesterase Inhibitory ActivityMolecules (Basel, Switzerland), 2023, v.28 no.6
(S)-5-Methylmellein Isolated from an Endogenous Lichen Fungus Rosellinia corticium as a Potent Inhibitor of Human Monoamine Oxidase APROCESSES, 2022, v.10 no.1, 166
Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces spJOURNAL OF ANTIBIOTICS, 2022, v.75 no.11, 619-625
Antibacterial Activity of Prenylated Flavonoids Isolated from Hop against Fish Pathogens Streptococcus iniae and Vibrio vulnificusBiotechnology and Bioprocess Engineering, 2022, v.27 no.3, 361-369
Discovery and Photoisomerization of New Pyrrolosesquiterpenoids Glaciapyrroles D and E, from Deep-Sea Sediment Streptomyces sp.Marine Drugs, 2022, v.20 no.5, 281
Gwanakosides A and B, 6-Deoxy-α-l-talopyranose-Bearing Aromatic Metabolites from a Streptomyces sp. and Coculture with Pandoraea sp.Journal of Natural Products, 2022, v.85 no.1, 83-90
Ligiamycins A and B, Decalin-Amino-Maleimides from the Co-Culture of Streptomyces sp. and Achromobacter sp. Isolated from the Marine Wharf Roach, Ligia exoticaMARINE DRUGS, 2022, v.20 no.2, 83
Marine Depsipeptide Nobilamide i Inhibits Cancer Cell Motility and Tumorigenicity via Suppressing Epithelial-Mesenchymal Transition and MMP2/9 ExpressionACS Omega, 2022, v.7 no.2, 1722-1732
SNA077, an Extract of Marine Streptomyces sp., Inhibits Melanogenesis by Downregulating Melanogenic Proteins via Inactivation of cAMP/PKA/CREB SignalingInternational Journal of Molecular Sciences, 2022, v.23 no.23, 14922
Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp.MARINE DRUGS, 2022, v.20 no.1, 35
Targeted Discovery of an Enediyne-Derived Cycloaromatized Compound, Jejucarboside A, from a Marine ActinomyceteOrganic Letters, 2022, v.24 no.39, 7188-7193
Acremonamide, a Cyclic Pentadepsipeptide with Wound-Healing Properties Isolated from a Marine-Derived Fungus of the Genus AcremoniumJOURNAL OF NATURAL PRODUCTS, 2021, v.84 no.8, 2249-2255
Acremonidin E produced by Penicillium sp. SNF123, a fungal endophyte of Panax ginseng, has antimelanogenic activitiesJOURNAL OF GINSENG RESEARCH, 2021 , 98-107
Antioxidative and anti-inflammatory activity of psiguadial B and its halogenated analogues as potential neuroprotective agentsBioorganic Chemistry, 2021, v.113, 105027
Azetidine-Bearing Non-Ribosomal Peptides, Bonnevillamides D and E, Isolated from a Carrion Beetle-Associated ActinomyceteJOURNAL OF ORGANIC CHEMISTRY, 2021, v.86 no.16, 11149-11159
Potent and Selective Inhibitors of Human Monoamine Oxidase A from an Endogenous Lichen Fungus Diaporthe mahothocarpusJOURNAL OF FUNGI, 2021, v.7 no.10, 876
Selective inhibition of human monoamine oxidase B by 5-hydroxy-2-methyl-chroman-4-one isolated from an endogenous lichen fungus Daldinia fissaJournal of Fungi, 2021, v.7 no.2, 1-16
An Activatable AIEgen Probe for High-Fidelity Monitoring of Overexpressed Tumor Enzyme Activity and Its Application to Surgical Tumor ExcisionANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, v.59 no.25, 10186-10195
Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer CellsJOURNAL OF NATURAL PRODUCTS, 2020, v.83 no.10, 3166-3172
Salvianolic Acid B Inhibits Hand-Foot-Mouth Disease Enterovirus 71 Replication through Enhancement of AKT Signaling PathwayJournal of microbiology and biotechnology, 2020, v.30 no.1, 38-43
Two new secondary metabolites, saccharochlorines A and B, from a marine bacterium Saccharomonospora sp. KCTC-19160BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, v.30 no.11, 127145
Gentiopicroside isolated from Gentiana scabra Bge. inhibits adipogenesis in 3T3-L1 cells and reduces body weight in diet-induced obese miceBioorganic and Medicinal Chemistry Letters, 2019, v.29 no.14, 1699-1704
Meroindenon and Merochlorins e and F, Antibacterial Meroterpenoids from a Marine-Derived Sediment Bacterium of the Genus StreptomycesOrganic Letters, 2019, v.21 no.15, 5779-5783
Mycousfurans A and B, antibacterial usnic acid congeners from the fungus Mycosphaerella sp., isolated from a marine sedimentMarine Drugs, 2019, v.17 no.7, 422
Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivativesInternational Journal of Biological Macromolecules, 2019, v.137, 426-432
Acetonic extracts of the endolichenic fungus EL002332 isolated from Endocarpon pusillum exhibits anticancer activity in human gastric cancer cellsPhytomedicine, 2018, v.40, 106-115
Decursin and Z-Ligustilide in Angelica tenuissima Root Extract Fermented by Aspergillus oryzae Display Anti-Pigment Activity in Melanoma CellsJOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2018, v.28 no.7, 1061-1067
Enantioselective Synthesis of a Novel Thiazoline Core as a Potent Peroxisome Proliferator-Activated Receptor δ AgonistACS Omega, 2018, v.3 no.2, 1970-1976
Naphthalene-based fluorescent probes for glutathione and their applications in living cells and patients with sepsisTHERANOSTICS, 2018, v.8 no.5, 1411-1420
Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificusJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, v.66 no.40, 10608-10616
4Z- and 4E-12-deoxydihydrokromycins, two naturally occurring kromycin aglycones of pikromycin from Streptomyces sp.Tetrahedron Letters, 2017, v.58 no.24, 2322-2324
A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristicsChemical Communications, 2017, v.53 no.35, 4791-4794
An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cellsCHEMICAL COMMUNICATIONS, 2017, v.53 no.3, 525-528
Cadiolides J–M, antibacterial polyphenyl butenolides from the Korean tunicate Pseudodistoma antinbojaBioorganic and Medicinal Chemistry Letters, 2017, v.27 no.3, 574-577
Enabling techniques in the search for new antibiotics: Combinatorial biosynthesis of sugar-containing antibioticsBIOCHEMICAL PHARMACOLOGY, 2017, v.134, 56-73
Identification of Antiangiogenic Potential and Cellular Mechanisms of Napyradiomycin A1 Isolated from the Marine-Derived Streptomyces sp YP127JOURNAL OF NATURAL PRODUCTS, 2017, v.80 no.8, 2269-2275
Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp.Bioorganic and Medicinal Chemistry Letters, 2017, v.27 no.14, 3123-3126
Potent Inhibition of Monoamine Oxidase B by a Piloquinone from Marine-Derived Streptomyces sp CNQ-027JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2017, v.27 no.4, 785-790
Potent Selective Inhibition of Monoamine Oxidase A by Alternariol Monomethyl Ether Isolated from Alternaria brassicaeJOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2017, v.27 no.2, 316-320
Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in TylosinJOURNAL OF NATURAL PRODUCTS, 2016, v.79 no.8, 2014-2021
Determination of process-related impurities in N-acetylglucosamine prepared by chemical and enzymatic methods: structural elucidation and quantificationARCHIVES OF PHARMACAL RESEARCH, 2016, v.39 no.7, 937-945
The Halicylindramides, Farnesoid X Receptor Antagonizing Depsipeptides from a Petrosia sp Marine Sponge Collected in KoreaJOURNAL OF NATURAL PRODUCTS, 2016, v.79 no.3, 499-506
A non-immunosuppressive FK506 analogue with neuroregenerative activity produced from a genetically engineered Streptomyces strainRSC ADVANCES, 2015, v.5 no.9, 6823-6828
Acredinones A and B, Voltage-Dependent Potassium Channel Inhibitors from the Sponge-Derived Fungus Acremonium sp F9A015JOURNAL OF NATURAL PRODUCTS, 2015, v.78 no.3, 363-367
Simultaneous analysis of seven 2-hydroxy fatty acids as tert-butyldimethylsilyl derivatives in plasma by gas chromatography-mass spectrometryBIOMEDICAL CHROMATOGRAPHY, 2015, v.29 no.1, 156-160
Utilization of circular dichroism experiment to distinguish acanthoside D and eleutheroside eArchives of Pharmacal Research, 2015, v.38 no.11, 1921-1925
Anmindenols A and B, inducible nitric oxide synthase inhibitors from a marine-derived Streptomyces sp.Journal of Natural Products, 2014, v.77 no.6, 1528-1531
Phorbaketals L-N, cytotoxic sesterterpenoids isolated from the marine sponge of the genus PhorbasBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, v.24 no.17, 4095-4098
Placotylene A, an Inhibitor of the Receptor Activator of Nuclear Factor-.B Ligand-Induced Osteoclast Differentiation, from a Korean Sponge Placospongia sp.MARINE DRUGS, 2014, v.12 no.4, 2054-2065
[학술지논문] Tsaokoic Acid: A New Bicyclic Nonene from the Fruits of Amomum tsao-ko with Acetylcholinesterase Inhibitory Activity
MOLECULES, 2023, v.28
no.6
, 2602-2602