Professor Soo Young Lee received his PhD degree from Korea University, Korea. He conducted postdoctoral research at the Rockefeller University in New York, USA. He is currently Professor at the Department of Life Science, College of Natural Sciences, Ewha Womans University, Korea. His main research topics include inflammation, innate immunity and bone metabolism in inflammation- and aging-related bone disorders. He was a Principal Investigator of National Research Laboratory from 2008 to 2013. He has published more than 80 peer-reviewed articles in reputed internatioanl journals.
IgSF11 deficiency alleviates osteoarthritis in mice by suppressing early subchondral bone changesExperimental and Molecular Medicine, 2023, v.55 no.12, 2576-2585
Tetraspanin 7 regulates osteoclast function through association with the RANK/αvβ3 integrin complexJournal of Cellular Physiology, 2022, v.237 no.1, 846-855
Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1β expressionActa Pharmaceutica Sinica B, 2020, v.10 no.3, 462-474
Cinchonine inhibits osteoclast differentiation by regulating TAK1 and AKT, and promotes osteogenesisJournal of Cellular Physiology, 2020, v.236 no.3, 0
Deacetylation by SIRT1 promotes the tumor-suppressive activity of HINT1 by enhancing its binding capacity for beta-catenin or MITF in colon cancer and melanoma cellsEXPERIMENTAL AND MOLECULAR MEDICINE, 2020, v.52 no.7, 1075-1089
Intensive morphometric analysis of enormous alterations in skeletal bone system with micro-CT for AHNAK−/− miceAnatomical Science International, 2020, v.95 no.3, 323-333
Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axisEXPERIMENTAL AND MOLECULAR MEDICINE, 2020 , 1831-1844
Euphorbia factor L1 inhibits osteoclastogenesis by regulating cellular redox status and induces Fas-mediated apoptosis in osteoclastFree Radical Biology and Medicine, 2017, v.112, 191-199
A novel small-molecule PPI inhibitor targeting integrin alpha(v)beta(3)-osteopontin interface blocks bone resorption in vitro and prevents bone loss in miceBIOMATERIALS, 2016, v.98, 131-142
FlexPro MD, a Mixture of Krill Oil, Astaxanthin, and Hyaluronic Acid, Suppresses Lipopolysaccharide-Induced Inflammatory Cytokine Production Through Inhibition of NF-kappa BJOURNAL OF MEDICINAL FOOD, 2016, v.19 no.12, 1196-1203
ADP-ribosylation factor 1 regulates proliferation, migration, and fusion in early stage of osteoclast differentiationInternational Journal of Molecular Sciences, 2015, v.16 no.12, 29305-29314
NK cell function triggered by multiple activating receptors is negatively regulated by glycogen synthase kinase-3βCellular Signalling, 2015, v.27 no.9, 1731-1741
Tight junction protein 1 is regulated by transforming growth factor-beta and contributes to cell motility in NSCLC cellsBMB REPORTS, 2015, v.48 no.2, 115-120
[학술지논문] 5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPARγ axis
NATURE COMMUNICATIONS, 2024, v.15
no.1
, 1024-1024
SCIE
[학술지논문] Octyl gallate has potent anti-inflammasome activity by directly binding to NLRP3 LRR domain
JOURNAL OF CELLULAR PHYSIOLOGY, 2024, v.239
no.4
, 1-13
SCIE
[학술지논문] RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts
BONE RESEARCH, 2024, v.12
no.1
, 1-14
SCIE
[학술지논문] Pim1 promotes IFN-β production by interacting with IRF3
EXPERIMENTAL AND MOLECULAR MEDICINE, 2022, v.54
no.0
, 2092-2103
SCI
[학술지논문] Tetraspanin 7 regulates osteoclast function through association with the RANK/alpha v beta 3 integrin complex
JOURNAL OF CELLULAR PHYSIOLOGY, 2022, v.237
no.1
, 846-855
SCI
[학술지논문] Core promoter activity contributes to chromatin-based regulation of internal cryptic promoters
NUCLEIC ACIDS RESEARCH, 2021, v.49
no.14
, 8097-8109
SCI
[학술지논문] Early estrogen-induced gene 1 facilitates osteoclast formation through the inhibition of interferon regulatory factor 8 expression
FASEB JOURNAL, 2020, v.34
no.9
, 12894-12906