EWHA WOMANS UNIVERSITY

Wonhyo Seo Associate Professor

Pharmaceutical Sciences/Industrial Pharmaceutical Science/Division of Pharmacy

Director, Ewha Laboratory Animal Center
Pharmaceutical Science Building B #303
02-3277-3366
Research Interests
- alcoholic liver diseases, interaction between hepatic cells and non-parenchymal cells, Development of acute/chronic liver disease mouse model

Research Record

A novel A2a adenosine receptor inhibitor effectively mitigates hepatic fibrosis in a metabolic dysfunction-associated steatohepatitis mouse model International Journal of Biological Sciences, 2024, v.20 no.5, 1855-1870
SCIE Scopus dColl.
Aloe-derived nanovesicles attenuate inflammation and enhance tight junction proteins for acute colitis treatment Biomaterials Science, 2023, v.11 no.16, 5490-5501
SCIE Scopus dColl.
Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death, and Lipolysis Cellular and Molecular Gastroenterology and Hepatology, 2023, v.15 no.2, 281-306
SCIE Scopus dColl.
Exosomes: Nomenclature, Isolation, and Biological Roles in Liver Diseases Biomolecules and Therapeutics, 2023, v.31 no.3, 253-263
SCIE Scopus KCI dColl.
Experimental models of fatty liver diseases: Status and appraisal HEPATOLOGY COMMUNICATIONS, 2023, v.7 no.7, e00200
SCIE Scopus dColl.
Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis Journal of Medicinal Chemistry, 2023, v.66 no.23, 16342-16363
SCIE Scopus dColl.
Pomegranate-Derived Exosome-Like Nanovesicles Alleviate Binge Alcohol-Induced Leaky Gut and Liver Injury Journal of Medicinal Food, 2023, v.26 no.10, 739-748
SCIE Scopus KCI dColl.
Yam-derived exosome-like nanovesicles stimulate osteoblast formation and prevent osteoporosis in mice Journal of Controlled Release, 2023, v.355, 184-198
SCIE Scopus dColl.
Alcoholic liver disease: a new insight into the pathogenesis of liver disease Archives of Pharmacal Research, 2022, v.45 no.7, 447-459
KCI dColl.
Alcoholic liver disease: a new insight into the pathogenesis of liver disease Archives of Pharmacal Research, 2022, v.45 no.7, 447-459
SCIE Scopus KCI dColl.
Ellagic Acid Prevents Binge Alcohol-Induced Leaky Gut and Liver Injury through Inhibiting Gut Dysbiosis and Oxidative Stress ANTIOXIDANTS, 2021, v.10 no.9, 1386
SCIE Scopus dColl.
MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, v.17 no.4, 1153-1167
SCIE Scopus dColl.
Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223-enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis JOURNAL OF CLINICAL INVESTIGATION, 2021, v.131 no.3, e141513
SCIE Scopus dColl.
Disulfiram Treatment Normalizes Body Weight in Obese Mice CELL METABOLISM, 2020, v.32 no.2, 203-
SCIE Scopus dColl.
Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice JOURNAL OF HEPATOLOGY, 2020, v.72 no.4, 736-745
SCIE Scopus dColl.
Mitochondrial Double-Stranded RNA in Exosome Promotes Interleukin-17 Production Through Toll-Like Receptor 3 in Alcohol-associated Liver Injury HEPATOLOGY, 2020, v.72 no.2, 609-625
SCIE Scopus dColl.
Protective and Detrimental Roles of p38 alpha Mitogen-Activated Protein Kinase in Different Stages of Nonalcoholic Fatty Liver Disease HEPATOLOGY, 2020, v.72 no.3, 873-891
SCIE Scopus dColl.
[학술지논문] A novel A2a adenosine receptor inhibitor effectively mitigates hepatic fibrosis in a metabolic dysfunction-associated steatohepatitis mouse model INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2024, v.20 no.5 , 1855-1870
SCIE
[학술지논문] Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis JOURNAL OF CONTROLLED RELEASE, 2024, v.374 no.0 , 337-348
SCIE
[학술지논문] Aloe-derived nanovesicles attenuate inflammation and enhance tight junction proteins for acute colitis treatment BIOMATERIALS SCIENCE, 2023, v.11 no.16 , 5490-5501
SCIE
[학술지논문] Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death, and Lipolysis CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2023, v.15 no.2 , 281-306
SCIE
[학술지논문] Exosomes: Nomenclature, Isolation, and Biological Roles in Liver Diseases BIOMOLECULES & THERAPEUTICS, 2023, v.31 no.3 , 253-263
SCIE
[학술지논문] Experimental models of fatty liver diseases: Status and appraisal HEPATOLOGY COMMUNICATIONS, 2023, v.7 no.7 , 1-8
SCIE
[학술지논문] Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis JOURNAL OF MEDICINAL CHEMISTRY, 2023, v.66 no.23 , 16342-16363
SCIE
[학술지논문] Yam-derived exosome-like nanovesicles stimulate osteoblast formation and prevent osteoporosis in mice JOURNAL OF CONTROLLED RELEASE, 2023, v.355 no.0 , 184-198
SCIE
[학술지논문] Alcoholic liver disease: a new insight into the pathogenesis of liver disease ARCHIVES OF PHARMACAL RESEARCH, 2022, v.45 no.7 , 447-459
SCIE
[학술지논문] Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2022, v.46 no.12 , 2163-2176
SCI

2025-1st
- First-Year Seminar 강의 계획서 상세보기
  - Subject No 11401Class No 03
  - 1Year ( 1Credit , 1Hour) Mon 7~7
- Introduction to Pharmaceutical Research
  - Subject No 38940Class No 01
  - 2Year ( 1.5Credit , 1.5Hour) Thu 6~6 (PHM-A404)
  - Major Requisite
- Challenges in Global Health 강의 계획서 상세보기
  - Subject No 38962Class No 01
  - 3Year ( 1.5Credit , 1.5Hour) Thu 4~4 (POSCO)
- Challenges in Global Health 강의 계획서 상세보기
  - Subject No 38962Class No 02
  - 3Year ( 1.5Credit , 1.5Hour) Thu 5~5 (PHM-A404)
- Preventive Pharmaceutics Ⅰ 강의 계획서 상세보기
  - Subject No 38966Class No 01
  - 4Year ( 3Credit , 3Hour) Wed 3~3 (POSCO551) , Fri 6~6 (PHM-A104)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ 강의 계획서 상세보기
  - Subject No 38966Class No 02
  - 4Year ( 3Credit , 3Hour) Wed 5~5 (PHM-A400) , Fri 5~5 (PHM-A104)
  - Major Requisite
- Animal Pharmacy 강의 계획서 상세보기
  - Subject No 38972Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Thu 2~2 (PHM-A400)
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 38980Class No 01
  - 4Year ( 2Credit , 3Hour) Wed 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 38980Class No 02
  - 4Year ( 2Credit , 3Hour) Mon 6~9 (PHM-A303-1)
  - Major Requisite
- Challenges in Global Health 강의 계획서 상세보기
  - Subject No 39067Class No 01
  - 3Year ( 1.5Credit , 1.5Hour) Thu 4~4 (POSCO)
- Challenges in Global Health 강의 계획서 상세보기
  - Subject No 39067Class No 02
  - 3Year ( 1.5Credit , 1.5Hour) Thu 5~5 (PHM-A404)
- Preventive Pharmaceutics Ⅰ 강의 계획서 상세보기
  - Subject No 39071Class No 01
  - 4Year ( 3Credit , 3Hour) Wed 6~6 (PHM-A400) , Fri 3~3 (PHM-A100-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 39085Class No 01
  - 4Year ( 2Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Veterinary Pharmaceutical Sciences 강의 계획서 상세보기
  - Subject No AP677Class No 01
  - Year ( 3Credit , 3Hour)
2024-2nd
- Preventive Pharmaceutics II 강의 계획서 상세보기
  - Subject No 22513Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Mon 3~3 (PHM-A400)
  - Major Requisite
- Preventive Pharmaceutics II 강의 계획서 상세보기
  - Subject No 22513Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Mon 5~5 (POSCO462)
  - Major Requisite
- Preventive Pharmaceutics II 강의 계획서 상세보기
  - Subject No 22513Class No 03
  - 4Year ( 1.5Credit , 1.5Hour) Wed 4~4 (PHM-A100-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 01
  - 4Year ( 1.5Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 02
  - 4Year ( 1.5Credit , 3Hour) Wed 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 03
  - 4Year ( 1.5Credit , 3Hour) Mon 6~9 (PHM-A303-1)
  - Major Requisite
- Toxicology
  - Subject No 38961Class No 01
  - 3Year ( 3Credit , 3Hour) Mon 2~2 (PHM-A400) , Thu 5~5 (PHM-A404)
- Seminar for Pharmaceutical Sciences Ⅳ 강의 계획서 상세보기
  - Subject No G16889Class No 01
  - Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)
- Seminar for Pharmaceutical Sciences Ⅳ 강의 계획서 상세보기
  - Subject No G18241Class No 01
  - Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)
- Laboratory Animal Research for Drug Development 강의 계획서 상세보기
  - Subject No G18401Class No 01
  - Year ( 3Credit , 3Hour) Tue 4~5 (HAK-654)
  - Classroom Changed
2024-1st
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 01
  - 4Year ( 3Credit , 3Hour) Wed 3~3 (PHM-A100-1) , Fri 5~5 (PHM-A104)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 02
  - 4Year ( 3Credit , 3Hour) Wed 5~5 (POSCO552) , Fri 6~6 (PHM-A104)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 03
  - 4Year ( 3Credit , 3Hour) Wed 2~2 (PHM-A100-1) , Fri 3~3 (PHM-A100-1)
  - Major Requisite
- Toxicology
  - Subject No 36204Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Tue 2~2 (PHM-A400)
- Toxicology
  - Subject No 36204Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Tue 5~5 (POSCO)
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 01
  - 4Year ( 1.5Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 02
  - 4Year ( 1.5Credit , 3Hour) Wed 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 03
  - 4Year ( 1.5Credit , 3Hour) Mon 6~9 (PHM-A303-1)
  - Major Requisite
- Introduction to Pharmaceutical Research
  - Subject No 39045Class No 01
  - 2Year ( 1.5Credit , 1.5Hour) Thu 6~6 (PHM-A100-1)
2023-2nd
- Preventive Pharmaceutics II 강의 계획서 상세보기
  - Subject No 22513Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Mon 3~3 (POSCO551)
  - Major Requisite
- Preventive Pharmaceutics II 강의 계획서 상세보기
  - Subject No 22513Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Wed 3~3 (POSCO551)
  - Major Requisite
- Preventive Pharmaceutics II 강의 계획서 상세보기
  - Subject No 22513Class No 03
  - 4Year ( 1.5Credit , 1.5Hour) Wed 4~4 (POSCO551)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 01
  - 4Year ( 1.5Credit , 3Hour) Mon 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 02
  - 4Year ( 1.5Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 03
  - 4Year ( 1.5Credit , 3Hour) Wed 6~9 (PHM-A303-1)
  - Major Requisite
- Advanced Pharmacy Practice and Research I 강의 계획서 상세보기
  - Subject No 37154Class No 01
  - 6Year ( 4Credit , 200Hour)
  - Major Requisite
- Advanced Pharmacy Practice and Research Ⅱ 강의 계획서 상세보기
  - Subject No 37155Class No 01
  - 6Year ( 4Credit , 200Hour)
  - Major Requisite
- Advanced Pharmacy Practice and Research Ⅲ 강의 계획서 상세보기
  - Subject No 37156Class No 01
  - 6Year ( 4Credit , 200Hour)
  - Major Requisite
- Challenges in global health
  - Subject No 37802Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Tue 2~2 (PHM-A100-1)
- Challenges in global health
  - Subject No 37802Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Mon 2~2 (PHM-A104)
- Honors research
  - Subject No 37803Class No 01
  - 4Year ( 1Credit , 1Hour)
- Laboratory animal research for drug development
  - Subject No G18401Class No 01
  - Year ( 3Credit , 3Hour) Tue 4~5 (POSCO-358)
  - Classroom Changed
2023-1st
- First-Year Seminar 강의 계획서 상세보기
  - Subject No 11401Class No 02
  - 1Year ( 1Credit Wed 7~7
- Preventive Pharmaceutics Ⅰ 강의 계획서 상세보기
  - Subject No 22515Class No 01
  - 4Year ( 3Credit , 3Hour) Wed 3~3 (PHM-A100-1) , Fri 5~5 (PHM-A104)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ 강의 계획서 상세보기
  - Subject No 22515Class No 02
  - 4Year ( 3Credit , 3Hour) Wed 5~5 (POSCO552) , Fri 6~6 (PHM-A104)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ 강의 계획서 상세보기
  - Subject No 22515Class No 03
  - 4Year ( 3Credit , 3Hour) Wed 2~2 (PHM-A100-1) , Fri 3~3 (POSCO551)
  - Major Requisite
- Toxicology
  - Subject No 36204Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Tue 5~5 (PHM-A100-1)
- Toxicology
  - Subject No 36204Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Tue 2~2 (POSCO551)
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 01
  - 4Year ( 1.5Credit , 3Hour) Mon 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 02
  - 4Year ( 1.5Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ 강의 계획서 상세보기
  - Subject No 37126Class No 03
  - 4Year ( 1.5Credit , 3Hour) Wed 6~9 (PHM-A303-1)
  - Major Requisite
- Introduction to Pharmaceutical Research 강의 계획서 상세보기
  - Subject No 38940Class No 01
  - 2Year ( 1.5Credit , 1.5Hour) Thu 6~6 (PHM-A404)
  - Major Requisite
2022-2nd
- Preventive Pharmaceutics II
  - Subject No 22513Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Fri 4~4 (ECC)
  - Major Requisite
- Preventive Pharmaceutics II
  - Subject No 22513Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Fri 3~3 (ECC)
  - Major Requisite
- Preventive Pharmaceutics II
  - Subject No 22513Class No 03
  - 4Year ( 1.5Credit , 1.5Hour) Mon 2~2 (PHM-A104)
  - Major Requisite
- Preventive Pharmaceutics II
  - Subject No 22513Class No 04
  - 4Year ( 1.5Credit , 1.5Hour) Mon 2~2 (PHM-A104)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 01
  - 4Year ( 1.5Credit , 3Hour) Mon 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 02
  - 4Year ( 1.5Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 03
  - 4Year ( 1.5Credit , 3Hour) Wed 6~9 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 04
  - 4Year ( 1.5Credit , 3Hour) Tue 6~9 (PHM-A303-1)
  - Major Requisite
- Advanced Pharmacy Practice and Research Ⅲ
  - Subject No 37156Class No 01
  - 6Year ( 4Credit , 200Hour)
  - Major Requisite
- Challenges in global health
  - Subject No 37802Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Wed 4~4 (PHM-A400)
- Challenges in global health
  - Subject No 37802Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Fri 6~6 (PHM-A400)
- Challenges in global health
  - Subject No 37802Class No 03
  - 4Year ( 1.5Credit , 1.5Hour) Fri 6~6 (PHM-A400)
- Laboratory animal research for drug development
  - Subject No G18401Class No 01
  - Year ( 3Credit , 3Hour) Tue 2~3 (PHM-)
2022-1st
- First-Year Seminar
  - Subject No 11401Class No 05
  - 1Year ( 1Credit Mon 7~7
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 01
  - 4Year ( 3Credit , 3Hour) Wed 2~2 (POSCO161) , Fri 3~3 (POSCO161)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 02
  - 4Year ( 3Credit , 3Hour) Wed 3~3 (POSCO161) , Fri 5~5 (POSCO161)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 03
  - 4Year ( 3Credit , 3Hour) Wed 5~5 (POSCO261) , Fri 6~6 (POSCO261)
  - Major Requisite
- Preventive Pharmaceutics Ⅰ
  - Subject No 22515Class No 04
  - 4Year ( 3Credit , 3Hour) Wed 5~5 (POSCO261) , Fri 6~6 (POSCO261)
  - Major Requisite
- Toxicology
  - Subject No 36204Class No 01
  - 4Year ( 1.5Credit , 1.5Hour) Mon 3~3 (PHM-A400)
- Toxicology
  - Subject No 36204Class No 02
  - 4Year ( 1.5Credit , 1.5Hour) Fri 2~2 (PHM-A404)
- Toxicology
  - Subject No 36204Class No 03
  - 4Year ( 1.5Credit , 1.5Hour) Fri 2~2 (PHM-A404)
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 01
  - 4Year ( 1.5Credit , 3Hour) Wed 6~7 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 02
  - 4Year ( 1.5Credit , 3Hour) Mon 6~7 (PHM-A303-1)
  - Major Requisite
- Pharmaceutical Experiment Laboratory Ⅲ
  - Subject No 37126Class No 03
  - 4Year ( 1.5Credit , 3Hour) Tue 6~7 (PHM-A303-1)
  - Major Requisite
- Honors research
  - Subject No 37803Class No 01
  - 4Year ( 1Credit , 1Hour)

Academic Background

Korea Advanced Institute of Science & Technology 이학박사(의과학학제학)

University of Pretoria M.S.(수의학과)

Kyungpook Nat'l Univ. 수의학사(수의학과)

Work Experience

미국립보건원(NIH) 2016-06-15 ~ 2021-03-01

카이스트 2016-03-01 ~ 2016-06-14

Wonhyo Seo Associate Professor

Research Record

Courses

Academic Background

Work Experience