이화여자대학교

Dongmin Kang Professor

Life Sciences / Department of Life Science

강동민 프로필 사진 
Dongmin Kang is a professor of Department of Life Science and known as a molecular imaging expert. He has been working on researches for signaling role of reactive oxygen species (ROS) and ROS-related diseases using optical imaging tools. He got a Ph.D at the microbiology of Seoul National University and had worked as a postdoctoral fellow at UC Berkeley and Stanford University. He had worked as a director of imaging division at Korea Basic Science Institute, Chuncheon Center from 2003 to 2007. He has been working as a faculty member at Ewha Womans University since 2007. His lab focuses on ROS imaging, regulation of phosphoinositide signaling by ROS and cancer cell imaging. He served as a president from 2020 to 2021 and as a vice president and section director of the Korean Society of Molecular Imaging from 2006 to 2013 and published about 80 research articles (SCI). He is currently working in the field of bioimaging as the director of the Bioimaging Data Curation Center and the director of the Fluorescence Core Imaging Center.
  • dkang@ewha.ac.kr
  • Director, Fluorescence Core Imaging Center/Director, Bioimaging Data Curation Center
  • Science Building C #205
  • 02-3277-6634
  • Research Interests
    • Control of signal transduction by reactive oxygen species, Research on the mechanisms of pancreatic cancer Development and treatment, Imaging of tumor microenvironment
  • sdg03
Research Record
  • Endosomal H2O2 Molecules Act as Signaling Mediators in Akt/PKB Activation ANTIOXIDANTS, 2025, v.14 no.5, 594
    SCIE Scopus dColl.
  • Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis Redox Biology, 2024, v.71, 103097
    SCIE Scopus dColl.
  • The Versatile Roles of nc886, a Fascinating and Peculiar Regulatory Non-Coding RNA, in Cancer International Journal of Molecular Sciences, 2024, v.25 no.19, 10825
    SCIE Scopus dColl.
  • A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus Molecular Therapy - Oncolytics, 2022, v.24, 683-694
    SCIE Scopus dColl.
  • Diclofenac: A Nonsteroidal Anti-Inflammatory Drug Inducing Cancer Cell Death by Inhibiting Microtubule Polymerization and Autophagy Flux Antioxidants, 2022, v.11 no.5, 1009
    SCIE Scopus dColl.
  • Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-Kappa B survival machinery in cancer cells Redox Biology, 2022, v.51, 102293
    SCIE Scopus dColl.
  • A Basic Domain-Derived Tripeptide Inhibits MITF Activity by Reducing its Binding to the Promoter of Genes JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, v.141 no.10, 2459-2469
    SCIE Scopus dColl.
  • Endosomal mtorc2 is required for phosphoinositide-dependent akt activation in platelet-derived growth factor-stimulated glioma cells Cancers, 2021, v.13 no.10, 2405
    SCIE Scopus dColl.
  • CD99–PTPN12 axis suppresses actin cytoskeleton-mediated dimerization of epidermal growth factor receptor Cancers, 2020, v.12 no.10, 1-24
    SCIE Scopus dColl.
  • Diclofenac impairs autophagic flux via oxidative stress and lysosomal dysfunction: Implications for hepatotoxicity Redox Biology, 2020, v.37, 101751
    SCIE Scopus dColl.
  • Quantitative and qualitative analysis of autophagy flux using imaging BMB REPORTS, 2020, v.53 no.5, 241-247
    SCIE Scopus KCI dColl.
  • The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle ANTIOXIDANTS, 2020, v.9 no.4, 280
    SCIE Scopus dColl.
  • The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress Free Radical Biology and Medicine, 2020, v.148, 22-32
    SCIE Scopus dColl.
  • Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-alpha-Induced Apoptosis via Different Routes CELL REPORTS, 2019, v.26 no.8, 2194-
    SCIE Scopus dColl.
  • Accumulation of PtdIns(4)P at the Golgi mediated by reversible oxidation of the PtdIns(4)P phosphatase Sac1 by H2O2 Free Radical Biology and Medicine, 2019, v.130, 426-435
    SCIE Scopus dColl.
  • BAP1 promotes stalled fork restart and cell survival via INO80 in response to replication stress Biochemical Journal, 2019, v.476 no.20, 3053-3066
    SCIE Scopus dColl.
  • Bispecific anti-mPDGFR beta x cotinine scFv-C-kappa-scFv fusion protein and cotinine-duocarmycin can form antibody-drug conjugate-like complexes that exert cytotoxicity against mPDGFR beta expressing cells METHODS, 2019, v.154, 125-135
    SCIE Scopus dColl.
  • Dehydrocostus lactone suppresses osteoclast differentiation by regulating NFATc1 and inhibits osteoclast activation through modulating migration and lysosome function FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, v.33 no.8, 9685-9694
    SCIE Scopus dColl.
  • Improved dynamic monitoring of transcriptional activity during longitudinal analysis in the mouse brain Biology Open, 2019, v.8 no.1, bio037168
    SCIE Scopus dColl.
  • Inactivation of the PtdIns(4)P phosphatase Sac1 at the Golgi by H2O2 produced via Ca2+-dependent Duox in EGF-stimulated cells Free Radical Biology and Medicine, 2019, v.131, 40-49
    SCIE Scopus dColl.
  • The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis Experimental and Molecular Medicine, 2019, v.51 no.7, 78
    SCIE Scopus KCI dColl.
  • The Role of Peroxiredoxins in the Transduction of H 2 O 2 Signals Antioxidants and Redox Signaling, 2018, v.28 no.7, 537-557
    SCIE Scopus dColl.
  • Self-Assembled Tb3+ Complex Probe for Quantitative Analysis of ATP during Its Enzymatic Hydrolysis via Time-Resolved Luminescence in Vitro and in Vivo ACS APPLIED MATERIALS & INTERFACES, 2017, v.9 no.1, 722-729
    SCIE Scopus dColl.
  • The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice PLoS ONE, 2017, v.12 no.10
    SCIE Scopus dColl.
  • Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression JOURNAL OF CELL BIOLOGY, 2015, v.210 no.1, 23-33
    SCIE Scopus dColl.
  • Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, v.111 no.17, 6269-6274
    SCIE Scopus dColl.
  • Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of keap1 and prevent oxidative liver damage Cell Metabolism, 2013, v.17 no.1, 73-84
    SCIE Scopus dColl.
  • [학술지논문] Nanobody-Based Biotemplating Enables Nanoscale-Precision Metallization of Cellular, Tissue, and Plant Architectures ACS APPLIED MATERIALS & INTERFACES, 2026, v.18 no.20 , 28396-28409
    SCIE
  • [학술지논문] Endosomal H2O2 Molecules Act as Signaling Mediators in Akt/PKB Activation ANTIOXIDANTS, 2025, v.14 no.5 , 1-20
    SCIE
  • [학술지논문] The immune sensitivity caused by DUSP11, an RNA 5′-end maturation phosphatase, is adjusted by a human non-coding RNA, nc886 CELLULAR AND MOLECULAR LIFE SCIENCES, 2025, v.82 no.1 , 1-17
    SCIE
  • [학술지논문] Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis REDOX BIOLOGY, 2024, v.71 no.0 , 103097-103097
    SCIE
  • [학술지논문] RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts BONE RESEARCH, 2024, v.12 no.1 , 1-14
    SCIE
  • [학술지논문] The Versatile Roles of nc886, a Fascinating and Peculiar Regulatory Non-Coding RNA, in Cancer INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, v.25 no.19 , 1-16
    SCIE
  • [학술지논문] A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus MOLECULAR THERAPY-ONCOLYTICS, 2022, v.24 no.0 , 683-694
    SCIE
  • [학술지논문] Diclofenac: A Nonsteroidal Anti-Inflammatory Drug Inducing Cancer Cell Death by Inhibiting Microtubule Polymerization and Autophagy Flux ANTIOXIDANTS, 2022, v.11 no.5 , 1-20
    SCIE
  • [학술지논문] Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-Kappa B survival machinery in cancer cells REDOX BIOLOGY, 2022, v.51 no.102293 , 1-14
    SCIE
  • [학술지논문] Decoding the temporal nature of brain GR activity in the NF kappa B signal transition leading to depressive-like behavior MOLECULAR PSYCHIATRY, 2021, v.26 no.9 , 5087-5096
    SCI
  • [학술지논문] Endosomal mTORC2 Is Required for Phosphoinositide-Dependent AKT Activation in Platelet-Derived Growth Factor-Stimulated Glioma Cells CANCERS, 2021, v.13 no.10 , 1-22
    SCIE
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Courses

  • 2026-2nd

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 01
      • 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA203)

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 02
      • 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA203)

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 03
      • 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA203)

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 04
      • 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA203)

    • Molecular Medical Science

      • Subject No 36336Class No 01
      • 4Year ( 3Credit , 3Hour) Mon 5~5 (SCI-) , Wed 4~4 (102)
        • Syllabus(File)

    • Introduction to Cancer Biology

      • Subject No 38220Class No 01
      • 4Year ( 3Credit , 3Hour) Mon 2~2 (POSCO452) , Thu 3~3 (POSCO452)
        • Syllabus(File)

    • Special Topics in Cell Biology Ⅰ

      • Subject No G16950Class No 01
      • Year ( 3Credit , 3Hour) Fri 4~5 (SCI-C)

    • Advanced Cell Biology

      • Subject No G16993Class No 01
      • Year ( 3Credit , 3Hour) Tue 7~8 (SCI-C)
        • Syllabus(File)

  • 2026-1st

    • Cell Biology Ⅰ

      • Subject No 34229Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 2~2 (POSCO360) , Fri 3~3 (POSCO360)
        • Syllabus(File)

    • Cell Biology Ⅰ

      • Subject No 34229Class No 03
      • 3Year ( 3Credit , 3Hour) Mon 4~4 (POSCO366) , Thu 5~5 (POSCO366)
        • Syllabus(File)

    • Cell Biology of Tissues

      • Subject No 37121Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO361) , Fri 5~5 (POSCO361)
        • Syllabus(File)

    • Special Topics in Cell Biology Ⅱ

      • Subject No G16951Class No 01
      • Year ( 3Credit , 3Hour) Fri 7~8 (SCI-C)
        • Syllabus(File)

    • Advanced Research Biotechniques

      • Subject No G17373Class No 01
      • Year ( 3Credit , 3Hour) Fri 3~4 (SCI-C)
        • Syllabus(File)

  • 2025-2nd

    • Cell Biology Ⅱ

      • Subject No 34237Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 2~2 (POSCO361) , Fri 3~3 (POSCO361)
        • Syllabus(File)

    • Molecular Medical Science

      • Subject No 36336Class No 01
      • 4Year ( 3Credit , 3Hour) Mon 4~4 (SCI-AA) , Thu 5~5 (101)
        • Syllabus(File)

    • Introduction to Cancer Biology

      • Subject No 38220Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO360) , Fri 5~5 (POSCO360)
        • Syllabus(File)

    • Research for Life Science Ⅳ

    • Special Topics in Cell Biology Ⅰ

      • Subject No G16950Class No 01
      • Year ( 3Credit , 3Hour) Fri 4~5 (SCI-C)
        • Syllabus(File)

    • Advanced Cell Biology

      • Subject No G16993Class No 01
      • Year ( 3Credit , 3Hour) Tue 7~8 (SCI-C)
        • Syllabus(File)

  • 2025-1st

    • Cell Biology Ⅰ

      • Subject No 34229Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 6~6 (POSCO361) , Thu 4~4 (POSCO361)
        • Syllabus(File)

    • Experiments in Life Sciences Ⅲ

      • Subject No 35313Class No 01
      • 3Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA203)
        • Syllabus(File)

    • Experiments in Life Sciences Ⅲ

      • Subject No 35313Class No 02
      • 3Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA203)
        • Syllabus(File)

    • Cell Biology of Tissues

      • Subject No 37121Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO361) , Fri 5~5 (POSCO361)
        • Syllabus(File)

    • Special Topics in Cell Biology Ⅱ

      • Subject No G16951Class No 01
      • Year ( 3Credit , 3Hour) Fri 7~8 (SCI-C)
        • Syllabus(File)

    • Advanced Research Biotechniques

      • Subject No G17373Class No 01
      • Year ( 3Credit , 3Hour) Fri 3~4 (SCI-C)
        • Syllabus(File)

  • 2024-1st

    • General Biology Ⅰ

      • Subject No 20413Class No 03
      • 1Year ( 3Credit , 3Hour) Mon 4~4 (POSCO452) , Thu 5~5 (POSCO452)
        • Syllabus(File)

    • Cell Biology Ⅰ

      • Subject No 34229Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 6~6 (POSCO361) , Thu 4~4 (POSCO361)
        • Syllabus(File)

    • Cell Biology Ⅰ

      • Subject No 34229Class No 03
      • 3Year ( 3Credit , 3Hour) Tue 3~3 (POSCO366) , Thu 2~2 (POSCO366)
        • Syllabus(File)

    • Cell Biology of Tissues

      • Subject No 37121Class No 01
      • 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO366) , Fri 5~5 (POSCO366)
        • Syllabus(File)

    • Special Topics in Cell Biology Ⅱ

      • Subject No G16951Class No 01
      • Year ( 3Credit , 3Hour) Fri 7~8 (SCI-C)
        • Syllabus(File)

    • Advanced Research Biotechniques

      • Subject No G17373Class No 01
      • Year ( 3Credit , 3Hour) Fri 3~4 (SCI-C)
        • Syllabus(File)

  • 2023-2nd

  • 2023-1st

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Academic Background

Seoul Nat'l Univ. 이학박사(미생물학)

Seoul Nat'l Univ. 이학석사(미생물학)

Seoul Nat'l Univ. 이학사(미생물학)

Work Experience

Director, Fluorescence Core Imaging Center 2019-11-01 ~ 2027-07-31

바이오이미징 데이터 품질선도센터 소장 2023-05-01 ~ 2027-01-31

Department Chair, Life Sciences 2018-02-01 ~ 2019-03-31

한국기초과학지원연구원/책임연구원 2003-09-01 ~ 2007-08-31

Standford Univ./Po-doc. 2001-04-01 ~ 2003-08-31

서울대,Univ.of California/Po-doc. 1997-03-01 ~ 2001-02-28

Internal Awards

연구비우수2026-03-01

연구비우수2025-03-01

연구비우수2024-03-01

연구비우수2023-03-01

연구비우수2022-03-01

External Awards

Minister of Science and ICT Award (과학기술정보통신부)2025-12-19