이화여자대학교

Roh Tae-Young Professor

Life Sciences / Department of Life Science

노태영 프로필 사진 
Professor Tae-Young Roh has been appointed since March 2023 to the “LIVE Research Center” (Director: Woojin Chung), a leading division of Ewha Womans University’s Ewha Frontier 10-10 Program, as a distinguished expert in epigenomic analysis utilizing next-generation omics technologies. He is conducting research on the regulation of gene expression mediated by epigenetic factors in cancer and stem cells.
He received his Ph.D. in Chemistry (Biochemistry) from Seoul National University and subsequently served as a Research Fellow at the U.S. National Institutes of Health (NIH). From July 2008 to February 2023, he was a faculty member in the Department of Life Sciences at Pohang University of Science and Technology (POSTECH).
Amid growing global efforts and investment to overcome cancer, his research focuses on epigenetic mechanisms of tumorigenesis and cell fate determination. In particular, he integrates bio-big data and advanced bioinformatics approaches with experimental systems, including organoids and mouse disease models, to develop innovative strategies for cancer therapy.
  • tyroh@ewha.ac.kr
  • Science Building A #A211
  • 0232773890
  • Research Interests
    • Epigenetics, Genomics, Molecular Biology, Biochemistry, Bioinformatics
  • sdg03
Research Record
  • Cyclin-dependent kinase inhibitor p18 regulates lineage transitions of excitatory neurons, astrocytes, and interneurons in the mouse cortex EMBO JOURNAL, 2025, v.44 no.2, 382-412
    SCIE Scopus dColl.
  • Deciphering single-cell genomic architecture: insights into cellular heterogeneity and regulatory dynamics Genomics and Informatics, 2025, v.23 no.1, 5
    Scopus dColl.
  • Formyl-methionine-mediated eukaryotic ribosome quality control pathway for cold adaptation MOLECULAR CELL, 2025, v.85 no.3
    SCIE Scopus dColl.
  • Noncanonical association of EZH2 with E2F1 promotes tumor proliferation through chromatin remodeling EXPERIMENTAL AND MOLECULAR MEDICINE, 2025, v.57 no.12, 2886-2897
    SCIE Scopus KCI dColl.
  • Nutrient starvation-induced Hda1C rewiring: coordinated regulation of transcription and translation NUCLEIC ACIDS RESEARCH, 2025, v.53 no.7, gkaf256
    SCIE Scopus dColl.
  • Hypoxia-inducible factor-1α-deficient adipose-tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein-1 Laboratory Animal Research, 2024, v.40 no.4, 408-423
    KCI dColl.
  • Hypoxia-inducible factor-1α-deficient adipose-tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein-1 Laboratory Animal Research, 2024, v.40 no.1, 37
    Scopus KCI dColl.
  • Longitudinal analysis of genetic and epigenetic changes in human pluripotent stem cells in the landscape of culture-induced abnormality Experimental and Molecular Medicine, 2024, v.56 no.11, 2409-2422
    SCIE Scopus KCI dColl.
  • YAP promotes global mRNA translation to fuel oncogenic growth despite starvation Experimental and Molecular Medicine, 2024, v.56 no.10, 2202-2215
    SCIE Scopus KCI dColl.
  • Forkhead box protein D2 suppresses colorectal cancer by reprogramming enhancer interactions Nucleic acids research, 2023, v.51 no.12, 6143-6155
    SCIE Scopus dColl.
  • [학술지논문] Cyclin-dependent kinase inhibitor p18 regulates lineage transitions of excitatory neurons, astrocytes, and interneurons in the mouse cortex EMBO JOURNAL, 2025, v.44 no.2 , 382-412
    SCIE
  • [학술지논문] Deciphering single-cell genomic architecture: insights into cellular heterogeneity and regulatory dynamics Genomics and Informatics, 2025, v.23 no.1 , 5-5
    Scopus
  • [학술지논문] Formyl-methionine-mediated eukaryotic ribosome quality control pathway for cold adaptation MOLECULAR CELL, 2025, v.85 no.3 , 602-619
    SCIE
  • [학술지논문] Noncanonical association of EZH2 with E2F1 promotes tumor proliferation through chromatin remodeling EXPERIMENTAL AND MOLECULAR MEDICINE, 2025, v.57 no.12 , 2886-2897
    SCIE
  • [학술지논문] Longitudinal analysis of genetic and epigenetic changes in human pluripotent stem cells in the landscape of culture-induced abnormality EXPERIMENTAL AND MOLECULAR MEDICINE, 2024, v.56 no.11 , 2409-2422
    SCIE
  • [학술지논문] ChIP-Seq Strategy to Identify Z-DNA-Forming Sequences in the Human Genome Methods in Molecular Biology, 2023, v.2651 no.2651 , 167-177
    Scopus
  • [학술지논문] DDM1-mediated gene body DNA methylation is associated with inducible activation of defense-related genes in Arabidopsis GENOME BIOLOGY, 2023, v.24 no.1 , 106-106
    SCIE
  • [학술지논문] Forkhead box protein D2 suppresses colorectal cancer by reprogramming enhancer interactions NUCLEIC ACIDS RESEARCH, 2023, v.51 no.12 , 6143-6155
    SCIE
  • [학술발표] Deciphering the Mechanisms of FOXD2-Mediated Chromatin Remodeling in Normal Colon and Cancer The 32nd International KOGO Annual Conference, 대한민국, 서울, 2023-10-13 한국유전체학회, 2023
  • [학술발표] Differential Accessibility Driving Gene Expression Changes in Culture-Adapted Variants with Copy Number Variation The 32nd International KOGO Annual Conference, 대한민국, 서울, 2023-10-13 한국유전체학회, 2023
  • [학술발표] Identification of a novel chromatin tuning factor by analyzing chromatin interactions KSBMB International Conference 2023, 대한민국, 부산, 2023-05-11 KSBMB International Conference 2023, 2023
  • [학술발표] Identification of a novel chromatin tuning factor, FOXD2 by analyzing enhancer interactions 제78회 한국생물과학협회 정기학술대회, 대한민국, 춘천, 2023-08-10 한국유전학회, 2023
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Courses

  • 2026-1st

  • 2025-2nd

    • Molecular Biology Ⅰ 강의 계획서 상세보기

      • Subject No 20600Class No 02
      • 2Year ( 3Credit , 3Hour) Mon 3~3 (POSCO366) , Wed 2~2 (POSCO366)
        • 영문계획안

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 01
      • 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA205)
        • Syllabus(File)

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 02
      • 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA205)
        • Syllabus(File)

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 03
      • 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA205)
        • Syllabus(File)

    • Experiments in Life Sciences Ⅱ

      • Subject No 35312Class No 04
      • 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA205)
        • Syllabus(File)

    • Life Science Seminar Ⅳ

      • Subject No G16931Class No 01
      • Year ( 3Credit , 3Hour) Thu 3~4 (SCI-C)
        • Syllabus(File)

    • Research for Life Science Ⅱ

    • Special Topics in Advanced Biochemistry Ⅱ

      • Subject No G16949Class No 01
      • Year ( 3Credit , 3Hour) Thu 5~6 (SCI-C)
        • Syllabus(File)

  • 2025-1st

  • 2024-2nd

    • General Biology

      • Subject No 20412Class No 01
      • 1Year ( 3Credit , 3Hour) Wed 3~3 (SCI-AA) , Fri 2~2 (102)
        • Syllabus(File)

    • Molecular Biology Ⅰ

      • Subject No 20600Class No 02
      • 2Year ( 3Credit , 3Hour) Mon 3~3 (POSCO365) , Wed 2~2 (POSCO365)
        • Syllabus(File)

    • Research for Life Science Ⅱ

    • Special Topics in Advanced Biochemistry Ⅱ

      • Subject No G16949Class No 01
      • Year ( 3Credit , 3Hour) Thu 5~6 (SCI-C)
        • Syllabus(File)

  • 2024-1st

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Academic Background

Seoul Nat'l Univ. 이학박사(화학과)

Work Experience

포항공대 2008-07-21 ~ 2023-02-28

미국 국립보건원 (NIH/NHLBI) 2002-11-15 ~ 2008-07-18

Director, Division of Life Sciences, Basic Research Directorate, National Research Foundation of Korea (NRF) 2022-02-15 ~ 2024-02-14

Internal Awards

이화펠로우2026-03-01

이화펠로우2023-03-01

External Awards

(한국유전체학회)2025-09-04

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