이화여자대학교

Kihyun Lee Assistant Professor

Pharmaceutical Sciences/Division of Pharmacy/Industrial Pharmaceutical Science

이기현 프로필 사진 
Dr. Kihyun Lee is an expert of disease modeling using human pluripotent stem cells. After the completion of her B.S. and M.S. at Ewha Womans University, she entered Weill Cornell Medicine for her phd study. She studied the genetics of pancreatic development using human pluripotent stem cells and her study helped in-depth understanding of genetic cause of neonatal diabetes. During her postdoctoral training at Gladstone Institutes located in San Francisco, she investigated the genetic cause of congenital heart diseases using whole-exome sequencing data. In her own laboratory, she will continue studying disease etiology using patient-derived data and pluripotent stem cells. Please visit the following link for more details. https://sites.google.com/view/kihyunlee
  • Science Building A #A116
  • 02-3277-2467
  • Research Interests
    • Genetics, Stem Cell Biology, Developmental Biology, Regenerative Medicine, Cell Therapy
Research Record
  • Pancreatic Diseases: Genetics and Modeling Using Human Pluripotent Stem Cells INTERNATIONAL JOURNAL OF STEM CELLS, 2024, v.17 no.3, 253-269
    SCIE Scopus dColl.
  • [학술지논문] GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis ELIFE, 2025, v.0 no.0 , 0-0
  • [학술지논문] Pancreatic Diseases: Genetics and Modeling Using Human Pluripotent Stem Cells INTERNATIONAL JOURNAL OF STEM CELLS, 2024, v.17 no.3 , 253-269
    SCIE
  • [학술지논문] QSER1 protects DNA methylation valleys from de novo methylation SCIENCE, 2021, v.372 no.6538 , 146-146
    SCI
  • [학술지논문] FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation Cell Reports, 2019, v.28 no.2 , 382-393.e7
    SCIE
  • [학술지논문] Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development Cell Stem Cell, 2017, v.20 no.5 , 675-688.e6
    SCI
  • [학술지논문] Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes CELL STEM CELL, 2016, v.18 no.6 , 755-768
    SCI
  • [학술지논문] Leptin Receptor Signaling in T Cells Is Required for Th17 Differentiation JOURNAL OF IMMUNOLOGY, 2015, v.194 no.11 , 5253-5260
    SCI
  • [학술지논문] Ablation of Peroxiredoxin II Attenuates Experimental Colitis by Increasing FoxO1-Induced Foxp3(+) Regulatory T Cells JOURNAL OF IMMUNOLOGY, 2013, v.191 no.8 , 4029-4037
    SCI
  • [학술지논문] Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+and Th/Treg cells PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, v.108 no.23 , 9548-9553
    SCI
  • [학술지논문] Glutathione Peroxidase 1 Deficiency Attenuates Allergen-Induced Airway Inflammation by Suppressing Th2 and Th17 Cell Development ANTIOXIDANTS & REDOX SIGNALING, 2010, v.13 no.5 , 575-587
    SCI
  • [학술지논문] In vivo tumor suppression activity by T cell-specific T-bet restoration INTERNATIONAL JOURNAL OF CANCER, 2010, v.127 no.. , 2129-2137
    SCI
  • [학술지논문] Anti-inflammatory activity of p-coumaryl alcohol-γ-O-methyl ether is mediated through modulation of interferon-γ production in Th cells British Journal of Pharmacology, 2009, v.156 no.7 , 1107-1114
    Scopus
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Courses

  • 2025-2nd

    • K-MOOC:Unlocking the Future: CRISPR Gene Editing

    • Advanced Pharmacy Practice and Research I

      • Subject No 37154Class No 02
      • 6Year ( 4Credit , 200Hour)
      • Major Requisite
        • Syllabus(File)

    • Advanced Pharmacy Practice and Research Ⅱ

      • Subject No 37155Class No 02
      • 6Year ( 4Credit , 200Hour)
      • Major Requisite
        • Syllabus(File)

    • Advanced Pharmacy Practice and Research Ⅲ

      • Subject No 37156Class No 02
      • 6Year ( 4Credit , 200Hour)
      • Major Requisite
        • Syllabus(File)

    • AAPS biotechnology fundamentals of biotherapeutics development

      • Subject No 37815Class No 01
      • 6Year ( 1.5Credit , 1.5Hour)
        • Syllabus(File)

    • Genetics and Disease

      • Subject No 38923Class No 01
      • 1Year ( 1.5Credit , 1.5Hour) Wed 2~2 (POSCO462)
        • Syllabus(File)

    • Pharmaceutical Microbiology Ⅱ

      • Subject No 38957Class No 01
      • 3Year ( 1.5Credit , 1.5Hour) Thu 2~2 (HAK553)
      • Major Requisite,Language Changed
        • Syllabus(File)

    • Pharmaceutical Microbiology Ⅱ

      • Subject No 38957Class No 02
      • 3Year ( 1.5Credit , 1.5Hour) Thu 4~4 (POSCO359)
      • Major Requisite,Language Changed
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 01
      • 3Year ( 2Credit , 3Hour) Tue 6~9 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 02
      • 3Year ( 2Credit , 3Hour) Wed 6~9 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Genetics and Disease

      • Subject No 39028Class No 01
      • 1Year ( 1.5Credit , 1.5Hour) Wed 3~3 (POSCO462)
        • Syllabus(File)

    • Pharmaceutical Microbiology Ⅱ

      • Subject No 39062Class No 01
      • 3Year ( 1.5Credit , 1.5Hour) Fri 4~4 (PHM-A100-1)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 39069Class No 01
      • 3Year ( 2Credit , 3Hour) Mon 6~9 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Understanding and Application of Bioinformatics and Chemoinformatics 강의 계획서 상세보기

      • Subject No G18091Class No 01
      • Year ( 3Credit , 3Hour) Fri 5~6 (PHM-)
        • Syllabus(File)

    • Global Advanced Technologies and Trends in Drug Development

  • 2025-1st

    • First-Year Seminar

      • Subject No 11401Class No 05
      • 1Year ( 1Credit , 1Hour) Mon 7~7 (SCI-AA116)
        • Syllabus(File)

    • K-MOOC:Unlocking the Future: CRISPR Gene Editing

    • Cancer Biology 강의 계획서 상세보기

      • Subject No 38952Class No 01
      • 3Year ( 1.5Credit , 1.5Hour) Wed 2~2 (PHM-A404)
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 01
      • 3Year ( 2Credit , 3Hour) Mon 6~9 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 02
      • 3Year ( 2Credit , 3Hour) Tue 6~9 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Introduction to Pharmaceutical Research

      • Subject No 39045Class No 01
      • 2Year ( 1.5Credit , 1.5Hour) Thu 6~6 (PHM-A104)
        • Syllabus(File)

    • Cancer Biology 강의 계획서 상세보기

      • Subject No 39057Class No 01
      • 3Year ( 1.5Credit , 1.5Hour) Wed 4~4 (PHM-A100-1)
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 39069Class No 01
      • 3Year ( 2Credit , 3Hour) Wed 6~9 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Stem Cells in Regenerative Medicine

      • Subject No G16907Class No 01
      • Year ( 3Credit , 3Hour) Fri 5~6 (PHM-)
        • Syllabus(File)

    • Seminar for Pharmaceutical Sciences Ⅰ

      • Subject No G18238Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)

    • Seminar for Pharmaceutical Sciences Ⅴ

      • Subject No G18823Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)

  • 2024-2nd

    • K-MOOC:Unlocking the Future: CRISPR Gene Editing 강의 계획서 상세보기

      • Subject No 11467Class No 01
      • Year ( 2Credit , 2Hour)

    • Advanced Pharmacy Practice and Research I

      • Subject No 37154Class No 02
      • 6Year ( 4Credit , 200Hour)
      • Major Requisite
        • Syllabus(File)

    • Advanced Pharmacy Practice and Research Ⅱ

      • Subject No 37155Class No 02
      • 6Year ( 4Credit , 200Hour)
      • Major Requisite
        • Syllabus(File)

    • Advanced Pharmacy Practice and Research Ⅲ

      • Subject No 37156Class No 02
      • 6Year ( 4Credit , 200Hour)
      • Major Requisite
        • Syllabus(File)

    • AAPS biotechnology fundamentals of biotherapeutics development 강의 계획서 상세보기

      • Subject No 37815Class No 01
      • 6Year ( 1.5Credit , 1.5Hour)

    • Genetics and Disease 강의 계획서 상세보기

      • Subject No 38923Class No 01
      • 1Year ( 1.5Credit , 1.5Hour) Tue 2~2 (POSCO152)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 01
      • 3Year ( 2Credit , 3Hour) Tue 6~7 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 02
      • 3Year ( 2Credit , 3Hour) Wed 6~7 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Genetics and Disease 강의 계획서 상세보기

      • Subject No 39028Class No 01
      • 1Year ( 1.5Credit , 1.5Hour) Tue 5~5 (POSCO462)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 39069Class No 01
      • 3Year ( 2Credit , 3Hour) Mon 6~7 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Understanding and Application of Bioinformatics and Chemoinformatics

      • Subject No G18091Class No 01
      • Year ( 3Credit , 3Hour) Fri 4~5 (PHM-)
        • Syllabus(File)

  • 2024-1st

    • K-MOOC:Unlocking the Future: CRISPR Gene Editing

    • Honors research

    • Introduction to Pharmaceutical Research

      • Subject No 38940Class No 01
      • 2Year ( 1.5Credit , 1.5Hour) Thu 6~6 (PHM-A404)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Microbiology Ⅰ

      • Subject No 38948Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 5~5 (POSCO462) , Thu 5~5 (POSCO462)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Microbiology Ⅰ

      • Subject No 38948Class No 02
      • 3Year ( 3Credit , 3Hour) Tue 2~2 (POSCO552) , Thu 2~2 (POSCO552)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 01
      • 3Year ( 2Credit , 3Hour) Mon 6~7 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 38964Class No 02
      • 3Year ( 2Credit , 3Hour) Tue 6~7 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Microbiology Ⅰ

      • Subject No 39053Class No 01
      • 3Year ( 3Credit , 3Hour) Tue 4~4 (POSCO462) , Thu 4~4 (POSCO462)
      • Major Requisite
        • Syllabus(File)

    • Pharmaceutical Sciences and Experiment Ⅱ

      • Subject No 39069Class No 01
      • 3Year ( 2Credit , 3Hour) Wed 6~7 (PHM-A307)
      • Major Requisite
        • Syllabus(File)

    • Stem Cells in Regenerative Medicine

      • Subject No G16907Class No 01
      • Year ( 3Credit , 3Hour) Fri 6~7 (PHM-)
        • Syllabus(File)

  • 2023-2nd

  • 2023-1st

    • Honors research

      • Subject No 37803Class No 01
      • 4Year ( 1Credit , 1Hour)

    • AAPS biotechnology fundamentals of biotherapeutics development

    • AAPS biotechnology fundamentals of biotherapeutics development

    • Introduction to Pharmaceutical Research 강의 계획서 상세보기

      • Subject No 39045Class No 01
      • 2Year ( 1.5Credit , 1.5Hour) Thu 6~6 (PHM-)
        • Syllabus(File)

    • Seminar for Pharmaceutical Sciences I

      • Subject No G16848Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A-404)
      • Classroom Changed
        • Syllabus(File)

    • Stem Cells in Regenerative Medicine

      • Subject No G16907Class No 01
      • Year ( 3Credit , 3Hour) Thu 2~3 (PHM-A-204)
      • Classroom Changed
        • Syllabus(File)

    • Seminar for Pharmaceutical Sciences Ⅰ

      • Subject No G18238Class No 01
      • Year ( 3Credit , 3Hour) Thu 7~8 (PHM-A400)
      • Classroom Changed
        • Syllabus(File)

  • 2022-2nd

    • Pharmaceutical Microbiology II

    • Pharmaceutical Microbiology II

    • Pharmaceutical Microbiology II

    • Genetics and Disease

      • Subject No 38923Class No 01
      • 1Year ( 1.5Credit , 1.5Hour) Tue 5~5 (POSCO)
        • Syllabus(File)

    • Genetics and Disease

      • Subject No 39028Class No 01
      • 1Year ( 1.5Credit , 1.5Hour) Tue 5~5 (POSCO)
        • Syllabus(File)
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Academic Background

Cornell University Ph.D.(Medical College)

Ewha Womans University 약학석사(생명약학부 약학전공)

Ewha Womans University 약학사(제약학)

Work Experience

Gladstone Institutes 2022-01-01 ~ 2022-08-31

Gladstone Institutes 2018-09-17 ~ 2021-12-31