Dr. Kihyun Lee is an expert of disease modeling using human pluripotent stem cells. After the completion of her B.S. and M.S. at Ewha Womans University, she entered Weill Cornell Medicine for her phd study. She studied the genetics of pancreatic development using human pluripotent stem cells and her study helped in-depth understanding of genetic cause of neonatal diabetes. During her postdoctoral training at Gladstone Institutes located in San Francisco, she investigated the genetic cause of congenital heart diseases using whole-exome sequencing data. In her own laboratory, she will continue studying disease etiology using patient-derived data and pluripotent stem cells. Please visit the following link for more details. https://sites.google.com/view/kihyunlee
[학술지논문] GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis
ELIFE, 2024, v.0
no.0
, 0-0
SCIE
[학술지논문] Pancreatic Diseases: Genetics and Modeling Using Human Pluripotent Stem Cells
INTERNATIONAL JOURNAL OF STEM CELLS, 2024, v.17
no.3
, 253-269
SCIE
[학술지논문] QSER1 protects DNA methylation valleys from de novo methylation
SCIENCE, 2021, v.372
no.6538
, 146-146
SCI
[학술지논문] FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation
Cell Reports, 2019, v.28
no.2
, 382-393.e7
SCIE
[학술지논문] Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development
Cell Stem Cell, 2017, v.20
no.5
, 675-688.e6
SCI
[학술지논문] Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes
CELL STEM CELL, 2016, v.18
no.6
, 755-768
SCI
[학술지논문] Leptin Receptor Signaling in T Cells Is Required for Th17 Differentiation
JOURNAL OF IMMUNOLOGY, 2015, v.194
no.11
, 5253-5260
SCI
[학술지논문] Ablation of Peroxiredoxin II Attenuates Experimental Colitis by Increasing FoxO1-Induced Foxp3(+) Regulatory T Cells
JOURNAL OF IMMUNOLOGY, 2013, v.191
no.8
, 4029-4037
SCI
[학술지논문] Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+and Th/Treg cells
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, v.108
no.23
, 9548-9553
SCI
[학술지논문] Glutathione Peroxidase 1 Deficiency Attenuates Allergen-Induced Airway Inflammation by Suppressing Th2 and Th17 Cell Development
ANTIOXIDANTS & REDOX SIGNALING, 2010, v.13
no.5
, 575-587
SCI
[학술지논문] In vivo tumor suppression activity by T cell-specific T-bet restoration
INTERNATIONAL JOURNAL OF CANCER, 2010, v.127
no..
, 2129-2137
SCI
[학술지논문] Anti-inflammatory activity of p-coumaryl alcohol-γ-O-methyl ether is mediated through modulation of interferon-γ production in Th cells
British Journal of Pharmacology, 2009, v.156
no.7
, 1107-1114