이혁진(李赫鎭) 교수

약학과[대학원] /약학부 /제약산업학과[대학원]

이혁진 프로필 사진
이혁진 교수는 약학대학 소속 약제학 및 물리약학 전공 교수이다. Johns Hopkins University (미), Columbia University (미) 및 KAIST에서 학/석/박사학위를 받았으며, 모더나 창업주인 MIT 대학의 Robert Langer 교수 지도 하에 siRNA 치료제 (Patisiran) 개발 및 핵산 구조체와 지질나노입자(LNP) 연구를 진행하였다. 2012년 본교 임용 후, 핵산 나노기술을 기반으로 한 차세대 RNA 핵산 치료제 (Dicer substrate RNA and IVT mRNA) 개발 및 체내 유전자 의약품 전달을 위한 3세대 지질나노입자(lipid nanoparticle) 발굴에 대한 연구를 진행하고 있다. 2013년 ~ 2014년 대한약학회 영문지 편집위원으로 활동하였으며, 2015년 ~ 2020년 공업화학회 영문지 편집위원, 그리고 2021년 Journal of Controlled Release 편집위원으로 활동 중이다.  현재까지 총 85여편의 논문을 SCI 국제학술지에 발표했다.
  • 미래산업약학전공주임교수
  • 약학관 A동 306호
  • 02-3277-3026
  • 연구관심분야
    • 약물전달 시스템, 유전자 치료제, 지질나노입자, 핵산 나노기술, mRNA
연구실적
  • [학술지논문] Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver SCIENCE ADVANCES, 2021, v.7 no.9 , 4398-4398
    SCI
  • Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood–brain-barrier penetration and tumor microenvironment modulation Journal of Nanobiotechnology, 2023, v.21 no.1, 253
    SCIE Scopus dColl.
  • Efficient Delivery of Globotriaosylceramide Synthase siRNA using Polyhistidine-Incorporated Lipid Nanoparticles Macromolecular Bioscience, 2023, v.23 no.4, 2200423
    SCIE Scopus dColl.
  • Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial-Mesenchymal Transition in the Lungs Advanced Functional Materials, 2023, v.33 no.7, 2209432
    SCIE Scopus dColl.
  • Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics Experimental and Molecular Medicine, 2023, v.55 no.10, 2085-2096
    SCIE Scopus KCI dColl.
  • In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector Molecular Therapy - Nucleic Acids, 2023, v.32, 161-172
    SCIE Scopus dColl.
  • In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice Molecular Therapy Nucleic Acids, 2023, v.34, 102050
    SCIE Scopus dColl.
  • Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications Advanced Drug Delivery Reviews, 2023, v.200, 114990
    SCIE Scopus dColl.
  • Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety Bioengineering and Translational Medicine, 2023, v.8 no.6, e10556
    SCIE Scopus dColl.
  • Anisotropic Plasmonic Gold Nanorod-Indocyanine Green@Reduced Graphene Oxide-Doxorubicin Nanohybrids for Image-Guided Enhanced Tumor Theranostics ACS Omega, 2022, v.7 no.17, 15186-15199
    SCIE Scopus dColl.
  • Artificial primary-miRNAs as a platform for simultaneous delivery of siRNA and antisense oligonucleotide for multimodal gene regulation Journal of Controlled Release, 2022, v.349, 983-991
    SCIE Scopus dColl.
  • In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy SCIENCE ADVANCES, 2022, v.8 no.3, eabj6901
    SCIE Scopus dColl.
  • Protein-RNA interaction guided chemical modification of Dicer substrate RNA nanostructures for superior in vivo gene silencing Journal of Controlled Release, 2022, v.343, 57-65
    SCIE Scopus dColl.
  • mRNA vaccines: the most recent clinical applications of synthetic mRNA Archives of Pharmacal Research, 2022, v.45 no.4, 245-262
    SCIE Scopus KCI dColl.
  • Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver SCIENCE ADVANCES, 2021, v.7 no.9, eabf4398
    SCIE Scopus dColl.
  • Plasmon-Triggered Upconversion Emissions and Hot Carrier Injection for Combinatorial Photothermal and Photodynamic Cancer Therapy ACS APPLIED MATERIALS & INTERFACES, 2021, v.13 no.49, 58422-58433
    SCIE Scopus dColl.
  • The core composition of DNA block copolymer micelles dictates DNA hybridization properties, nuclease stabilities, and cellular uptake efficiencies NANOSCALE, 2021, v.13 no.32, 13758-13763
    SCIE Scopus dColl.
  • Adjuvant incorporated lipid nanoparticles for enhanced mRNA-mediated cancer immunotherapy BIOMATERIALS SCIENCE, 2020, v.8 no.4, 1101-1105
    SCIE Scopus dColl.
  • Combined hybrid structure of siRNA tailed IVT mRNA (ChriST mRNA) for enhancing DC maturation and subsequent anticancer T cell immunity Journal of Controlled Release, 2020, v.327, 225-234
    SCIE Scopus dColl.
  • Highly selective detection of single nucleotide polymorphism (SNP) using a dumbbell DNA probe with a gap-filling approach Journal of Industrial and Engineering Chemistry, 2020, v.88, 78-83
    SCIE Scopus KCI dColl.
  • Nanoformulated Single-Stranded RNA-Based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer: Inducing Humoral Immune Response by Activation of Antigen-Presenting Cells Angewandte Chemie - International Edition, 2020, v.59 no.28, 11540-11549
    SCIE Scopus dColl.
  • Photocatalytic degradation of phenol using chemical vapor desposition graphene column Catalysts, 2020, v.10 no.11, 1-11
    SCIE Scopus dColl.
  • The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress FREE RADICAL BIOLOGY AND MEDICINE, 2020, v.148, 22-32
    SCIE Scopus dColl.
  • A dynamic DNA nanostructure with switchable and size-selective molecular recognition properties NANOSCALE, 2019, v.11 no.5, 2501-2509
    SCIE Scopus dColl.
  • Capillary Tube Based Molecular Diagnostic Test for Naked Eye Detection of Antibiotic Resistant Bacteria Advanced Materials Technologies, 2019, v.4 no.1, 1800375
    SCIE Scopus dColl.
  • Lamb wave-based molecular diagnosis using DNA hydrogel formation by rolling circle amplification (RCA) process Biosensors and Bioelectronics, 2019, v.142, 111496
    SCIE Scopus dColl.
  • Membrane Fusion through the Generation of Triazole Ceramide via Click Chemistry at the Membrane Surface ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, v.8 no.9, 1713-1717
    SCIE Scopus dColl.
  • Multicistronic IVT mRNA for simultaneous expression of multiple fluorescent proteins Journal of Industrial and Engineering Chemistry, 2019, v.80, 770-777
    SCIE Scopus KCI dColl.
  • Tonsil-derived stem cells as a new source of adult stem cells WORLD JOURNAL OF STEM CELLS, 2019, v.11 no.8, 506-518
    SCIE Scopus dColl.
  • Catalytic degradation of phenols by recyclable CVD graphene films NANOSCALE, 2018, v.10 no.13, 5840-5844
    SCIE Scopus dColl.
  • Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate Journal of Industrial and Engineering Chemistry, 2018, v.63, 103-111
    SCIE Scopus KCI dColl.
  • Development of mRNA vaccines and their prophylactic and therapeutic applications NANO RESEARCH, 2018, v.11 no.10, 5173-5192
    SCIE Scopus dColl.
  • Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine BIOMATERIALS, 2018, v.156, 172-193
    SCIE Scopus dColl.
  • Enhanced Chemical Reactivity of Graphene by Fermi Level Modulation CHEMISTRY OF MATERIALS, 2018, v.30 no.16, 5602-5609
    SCIE Scopus dColl.
  • Enhanced intracellular delivery of macromolecules by melittin derivatives mediated cellular uptake Journal of Industrial and Engineering Chemistry, 2018, v.58, 290-295
    SCIE Scopus KCI dColl.
  • Enzymatic Synthesis of Self-assembled Dicer Substrate RNA Nanostructures for Programmable Gene Silencing NANO LETTERS, 2018, v.18 no.7, 4279-4284
    SCIE Scopus dColl.
  • MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging BIOMATERIALS SCIENCE, 2018, v.6 no.10, 2619-2626
    SCIE Scopus dColl.
  • Mechanochemical synthesis of fluorescent carbon dots from cellulose powders NANOTECHNOLOGY, 2018, v.29 no.16
    SCIE Scopus dColl.
  • Synergistic Nanozymetic Activity of Hybrid Gold Bipyramid-Molybdenum Disulfide Core@Shell Nanostructures for Two-Photon Imaging and Anticancer Therapy ACS Applied Materials and Interfaces, 2018, v.10 no.49, 42068-42076
    SCIE Scopus dColl.
  • The cutting-edge technologies of siRNA delivery and their application in clinical trials ARCHIVES OF PHARMACAL RESEARCH, 2018, v.41 no.9, 867-874
    SCIE Scopus KCI dColl.
  • Aptamer-incorporated DNA Holliday junction for the targeted delivery of siRNA JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2017, v.56, 55-61
    SCIE Scopus KCI dColl.
  • Artificial Chemical Reporter Targeting Strategy Using Bioorthogonal Click Reaction for Improving Active-Targeting Efficiency of Tumor MOLECULAR PHARMACEUTICS, 2017, v.14 no.5, 1558-1570
    SCIE Scopus dColl.
  • Effects of tumor microenvironments on targeted delivery of glycol chitosan nanoparticles Journal of Controlled Release, 2017, v.267, 223-231
    SCIE Scopus dColl.
  • Extracellular matrix remodeling in vivo for enhancing tumor-targeting efficiency of nanoparticle drug carriers using the pulsed high intensity focused ultrasound Journal of Controlled Release, 2017, v.263, 68-78
    SCIE Scopus dColl.
  • Hydrogel Based Biosensors for In Vitro Diagnostics of Biochemicals, Proteins, and Genes Advanced Healthcare Materials, 2017, v.6 no.12
    SCIE Scopus dColl.
  • In vitro and in vivo behavior of DNA tetrahedrons as tumor-targeting nanocarriers for doxorubicin delivery COLLOIDS AND SURFACES B-BIOINTERFACES, 2017, v.157, 424-431
    SCIE Scopus dColl.
  • A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus Advanced Healthcare Materials, 2016, 22 June 2016
    SCIE Scopus dColl.
  • Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo Bioconjugate Chemistry, 2016, v.27 no.4, 927-936
    SCIE Scopus dColl.
  • Bioreducible Cationic Poly(amido amine)s for Enhanced Gene Delivery and Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2016, v.12 no.5, 1023-1034
    SCIE Scopus dColl.
  • Dual delivery of biological therapeutics for multimodal and synergistic cancer therapies Advanced Drug Delivery Reviews, 2016, v.98, 113-133
    SCIE Scopus dColl.
  • Gold-based hybrid nanomaterials for biosensing and molecular diagnostic applications BIOSENSORS & BIOELECTRONICS, 2016, v.80, 543-559
    SCIE Scopus dColl.
  • Microfluidics-Based Pathogen Detection: A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus (Adv. Healthcare Mater. 17/2016) Advanced Healthcare Materials, 2016, v.5 no.17, 2146
    SCIE Scopus dColl.
  • Near-infrared light-responsive nanomaterials for cancer theranostics Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2016, v.8 no.1, 23-45
    SCIE Scopus dColl.
  • Non-invasive stem cell tracking in hindlimb ischemia animal model using bio-orthogonal copper-free click chemistry Biochemical and Biophysical Research Communications, 2016, v.479 no.4, 779-786
    SCIE Scopus dColl.
  • Oligonucleotide-based biosensors for in vitro diagnostics and environmental hazard detection Analytical and Bioanalytical Chemistry, 2016, 18 JAN 2016, 1-24
    SCIE Scopus dColl.
  • PEGylation and HAylation via catechol: alpha-Amine-specific reaction at N-terminus of peptides and proteins ACTA BIOMATERIALIA, 2016, v.43, 50-60
    SCIE Scopus dColl.
  • Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs Journal of Controlled Release, 2016, v.243, 121-131
    SCIE Scopus dColl.
  • Technological development of structural DNA/RNA-based RNAi systems and their applications ADVANCED DRUG DELIVERY REVIEWS, 2016, v.104, 29-43
    SCIE Scopus dColl.
  • 고분자 전달체를 이용한 경폐 약물전달시스템 약 학 회 지, 2016, v.60 no.4, 173~179
    KCI dColl.
  • A fibrin-supported myocardial organ culture for isolation of cardiac stem cells via the recapitulation of cardiac homeostasis BIOMATERIALS, 2015, v.48, 66-83
    SCIE Scopus dColl.
  • Cathepsin B Imaging to Predict Quality of Engineered Cartilage Macromolecular Bioscience, 2015, v.15 no.9, 1224-1232
    SCIE Scopus dColl.
  • Co-delivery of VEGF and Bcl-2 dual-targeted siRNA polymer using a single nanoparticle for synergistic anti-cancer effects in vivo Journal of Controlled Release, 2015, 23 AUG 2015
    SCIE Scopus dColl.
  • Dendrimeric siRNA for efficient gene silencing Angewandte Chemie - International Edition, 2015, v.54 no.23, 6740-6744
    SCIE Scopus dColl.
  • DhITACT: DNA Hydrogel Formation by Isothermal Amplification of Complementary Target in Fluidic Channels ADVANCED MATERIALS, 2015, v.27 no.23, 3513-3517
    SCIE Scopus dColl.
  • Induced myogenic commitment of human chondrocytes via non-viral delivery of minicircle DNA JOURNAL OF CONTROLLED RELEASE, 2015, v.200, 212-221
    SCIE Scopus dColl.
  • Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells International Journal of Molecular Sciences, 2015, v.16 no.4, 7565-7576
    Scopus dColl.
  • Nanoparticle-Based Combination Therapy for Cancer Treatment CURRENT PHARMACEUTICAL DESIGN, 2015, v.21 no.22, 3158-3166
    SCIE Scopus dColl.
  • Near-infrared light-responsive nanomaterials for cancer theranostics Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2015, 2015
    SCIE Scopus dColl.
  • Osteogenic priming of mesenchymal stem cells by chondrocyte-conditioned factors and mineralized matrix CELL AND TISSUE RESEARCH, 2015, v.362 no.1, 115-126
    SCIE Scopus dColl.
  • Tonsil-derived Mesenchymal Stem Cells Ameliorate CCl4-induced Liver Fibrosis in Mice via Autophagy Activation SCIENTIFIC REPORTS, 2015, v.5
    SCIE Scopus dColl.
  • 3D Culture of Tonsil-Derived Mesenchymal Stem Cells in Poly(ethylene glycol)-Poly(L-alanine-co-L-phenyl alanine) Thermogel ADVANCED HEALTHCARE MATERIALS, 2014, v.3 no.11, 1782-1791
    SCIE dColl.
  • Biofunctional porous anodized titanium implants for enhanced bone regeneration JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2014, v.102 no.10, 3639-3648
    SCIE Scopus dColl.
  • Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 2014, v.5, 887-894
    SCIE Scopus dColl.
  • Efficient delivery of siRNAs by a photothermal approach using plant flavonoid-inspired gold nanoshells CHEMICAL COMMUNICATIONS, 2014, v.50 no.87, 13388-13390
    SCIE Scopus dColl.
  • Erratum: Efficient delivery of siRNAs by a photothermal approach using plant flavonoid-inspired gold nanoshells (Chemical Communications (2014) DOI: 10.1039/c4cc07155g) Chemical Communications, 2014, v.50 no.88, 13616
    SCIE Scopus dColl.
  • Gold nanoparticle (AuNP)-based drug delivery and molecular imaging for biomedical applications ARCHIVES OF PHARMACAL RESEARCH, 2014, v.37 no.1, 53-59
    SCIE KCI Scopus dColl.
  • Nanobiomaterials for pharmaceutical and medical applications ARCHIVES OF PHARMACAL RESEARCH, 2014, v.37 no.1, 1-3
    SCIE KCI Scopus dColl.
  • PH/redox/photo responsive polymeric micelle via boronate ester and disulfide bonds with spiropyran-based photochromic polymer for cell imaging and anticancer drug delivery European Polymer Journal, 2014, v.57, 1-10
    SCIE Scopus dColl.
  • Pyrogallol 2-Aminoethane: A Plant Flavonoid-Inspired Molecule for Material-Independent Surface Chemistry ADVANCED MATERIALS INTERFACES, 2014, v.1 no.4
    Scopus dColl.
  • Self-assembled DNA nanostructures prepared by rolling circle amplification for the delivery of siRNA conjugates CHEMICAL COMMUNICATIONS, 2014, v.50 no.86, 13049-13051
    SCIE Scopus dColl.
  • Tunable and selective detection of cancer cells using a betainized zwitterionic polymer with BODIPY and graphene oxide NEW JOURNAL OF CHEMISTRY, 2014, v.38 no.6, 2225-2228
    SCIE Scopus dColl.
  • Bio-inspired catechol chemistry: A new way to develop a re-moldable and injectable coacervate hydrogel Chemical Communications, 2012, v.48 no.97, 11895-11897
    SCIE Scopus dColl.
  • Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery Nature Nanotechnology, 2012, v.7 no.6, 389-393
    SCIE Scopus dColl.
  • [학술지논문] Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial-Mesenchymal Transition in the Lungs ADVANCED FUNCTIONAL MATERIALS, 2023, v.33 no.7 , 2209432-2209432
    SCIE
  • [지적재산권] TCTP-PTD를 포함하는 유전자 전달체 국내 : 특허, 등록, 10-1595152, 2016
  • [지적재산권] 생분해성 중합체, 이의 제조 방법, 이를 포함하는 유전자 전달 시스템 국내 : 특허, 등록, 10-1577893, 2015
  • [지적재산권] 표적 유전자 검출용 미세 유동 장치, 이의 제조방법 및 이를 이용한 검출 방법 국내 : 특허, 출원
  • [지적재산권] 핵산 나노구조체의 대량생산방법 및 이의 약물전달체로서의 활용 국내 : 특허, 출원
  • [지적재산권] 펩타이드 국내 : 특허, 등록
강의
  • 2024-2학기

    • 물리약학Ⅱ

      • 학수번호 38955분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 화 5~5 (약A104)
      • 전공필수 약학전공 1~55
    • 물리약학Ⅱ

      • 학수번호 38955분반 02
      • 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A104)
      • 전공필수 약학전공 56번 이후
    • 물리약학Ⅱ

      • 학수번호 39060분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A104)
      • 전공필수
    • 나노의약품및제형개발

      • 학수번호 G16896분반 01
      • 학년 ( 3학점 , 3시간) 수 6~7 (약A204)
  • 2024-1학기

    • 물리약학Ⅰ

      • 학수번호 38946분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A104)
      • 전공필수 약학전공 1~48
    • 물리약학Ⅰ

      • 학수번호 38946분반 02
      • 3학년 ( 1.5학점 , 1.5시간) 화 5~5 (약A104)
      • 전공필수 약학전공 49번이후
    • 산업약학입문

      • 학수번호 39045분반 01
      • 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약A100-1)
    • 물리약학Ⅰ

      • 학수번호 39051분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A104)
      • 전공필수
  • 2023-2학기

  • 2023-1학기

  • 2022-2학기

    • 물리약학Ⅱ

      • 학수번호 37123분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 화 2~2 (약A400)
      • 전공필수 학번 1~40
    • 물리약학Ⅱ

      • 학수번호 37123분반 02
      • 3학년 ( 1.5학점 , 1.5시간) 목 5~5 (약A400)
      • 전공필수 학번 41~80
    • 물리약학Ⅱ

      • 학수번호 37123분반 03
      • 3학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A400)
      • 전공필수 학번 81~120
    • 약학실습Ⅵ 강의 계획서 상세보기

      • 학수번호 37138분반 01
      • 5학년 ( 1.5학점 , 3시간) 월 6~9 (약A214)
      • 전공필수 팀티칭,학번 1~22, 집중이수(8주) 수업
    • 약학실습Ⅵ 강의 계획서 상세보기

      • 학수번호 37138분반 02
      • 5학년 ( 1.5학점 , 3시간) 화 6~9 (약A214)
      • 전공필수 팀티칭,학번 23~43, 집중이수(8주) 수업
    • 약학실습Ⅵ 강의 계획서 상세보기

      • 학수번호 37138분반 03
      • 5학년 ( 1.5학점 , 3시간) 수 6~9 (약A214)
      • 전공필수 팀티칭,학번 44~65, 집중이수(8주) 수업
    • 심화실습및연구Ⅰ

      • 학수번호 37154분반 01
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅰ

      • 학수번호 37154분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅱ

      • 학수번호 37155분반 01
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅱ

      • 학수번호 37155분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅲ

      • 학수번호 37156분반 01
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅲ

      • 학수번호 37156분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
      • 팀티칭, 산업제약학과 02반과 합반
    • Lab rotation Ⅰ

      • 학수번호 38927분반 01
      • 1학년 ( 1.5학점 , 0시간) 목 7~7
      • 팀티칭
    • Lab rotation Ⅰ

      • 학수번호 38927분반 02
      • 1학년 ( 1.5학점 목 7~7
      • 팀티칭
    • Lab rotation Ⅰ

      • 학수번호 39032분반 01
      • 1학년 ( 1.5학점 , 0시간) 목 7~7
      • 팀티칭
    • 실무프로젝트분석II

      • 학수번호 G16666분반 01
      • 학년 ( 3학점 , 3시간) 화 8~9 (약)
    • 신약개발세미나및실습IV

      • 학수번호 G16889분반 01
      • 학년 ( 3학점 , 3시간) 목 7~8 (약A400)
      • 교수결정
    • 신약개발세미나및실습Ⅳ

      • 학수번호 G18241분반 01
      • 학년 ( 3학점 , 3시간) 목 7~8 (약A400)
      • 교수결정
  • 2022-1학기

    • 물리약학I

      • 학수번호 22535분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 월 3~3 (약A104)
      • 전공필수 팀티칭/학번 1~40
    • 물리약학I

      • 학수번호 22535분반 02
      • 3학년 ( 1.5학점 , 1.5시간) 화 4~4 (약A404)
      • 전공필수 팀티칭/학번 41~80
    • 물리약학I

      • 학수번호 22535분반 03
      • 3학년 ( 1.5학점 , 1.5시간) 월 4~4 (약A104)
      • 전공필수 팀티칭/학번 81~120/산업제약학과 04반과 합반
    • 약물전달학

      • 학수번호 36213분반 01
      • 5학년 ( 1.5학점 , 1.5시간) 화 3~3 (약A400)
      • 전공필수,영어강의 팀티칭(1~43번)
    • 약물전달학

      • 학수번호 36213분반 02
      • 5학년 ( 1.5학점 , 1.5시간) 목 5~5 (약A404)
      • 전공필수,영어강의 팀티칭(44~86번)
    • 약물전달학

      • 학수번호 36213분반 03
      • 5학년 ( 1.5학점 , 1.5시간) 목 2~2 (약A400)
      • 전공필수,영어강의 팀티칭(87~130) / 산업제약학과 04반과 합반
    • 약물전달학

      • 학수번호 36213분반 04
      • 5학년 ( 1.5학점 , 1.5시간) 목 2~2 (약A400)
      • 전공필수,영어강의 추가개설/약학과 03반과 합반
    • 나노의약품및제형개발

      • 학수번호 G16896분반 01
      • 학년 ( 3학점 , 3시간) 수 5~6 (약)
  • 2021-2학기

    • 물리약학Ⅱ

      • 학수번호 37123분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 화 3~3
      • 전공필수,영어강의 학번 1~43
    • 물리약학Ⅱ

      • 학수번호 37123분반 02
      • 3학년 ( 1.5학점 , 1.5시간) 목 5~5
      • 전공필수,영어강의 학번 44~86
    • 물리약학Ⅱ

      • 학수번호 37123분반 03
      • 3학년 ( 1.5학점 , 1.5시간) 목 4~4
      • 전공필수,영어강의 학번 87~130, 산업제약학과 04반과 합반
    • 물리약학Ⅱ

      • 학수번호 37123분반 04
      • 3학년 ( 1.5학점 , 1.5시간) 목 4~4
      • 전공필수,영어강의 약학과 03반과 합반
    • 약학실습Ⅵ

      • 학수번호 37138분반 01
      • 5학년 ( 1.5학점 , 3시간) 월 6~9 (약A214)
      • 전공필수 집중이수(8주) 수업, 팀티칭,학번 1~22
    • 약학실습Ⅵ

      • 학수번호 37138분반 02
      • 5학년 ( 1.5학점 , 3시간) 화 6~9 (약A214)
      • 전공필수 집중이수(8주) 수업, 팀티칭,학번 23~43
    • 약학실습Ⅵ

      • 학수번호 37138분반 03
      • 5학년 ( 1.5학점 , 3시간) 수 6~9 (약A214)
      • 전공필수 집중이수(8주) 수업, 팀티칭,학번 44~65
    • 심화실습및연구Ⅲ

      • 학수번호 37156분반 02
      • 6학년 ( 4학점
      • 전공필수
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
      • 산업제약학과 02분반과 합반
  • 2021-1학기

    • 물리약학I

      • 학수번호 22535분반 01
      • 3학년 ( 1.5학점 , 1.5시간) 월 4~4
      • 전공필수,영어강의 팀티칭/학번1~43
    • 물리약학I

      • 학수번호 22535분반 02
      • 3학년 ( 1.5학점 , 1.5시간) 화 3~3
      • 전공필수,영어강의 팀티칭/학번 44~86
    • 물리약학I

      • 학수번호 22535분반 03
      • 3학년 ( 1.5학점 , 1.5시간) 화 5~5
      • 전공필수,영어강의 팀티칭/학번87~130/산업제약학과 04반과 합반
    • 물리약학I

      • 학수번호 22535분반 04
      • 3학년 ( 1.5학점 , 1.5시간) 화 5~5
      • 전공필수,영어강의 약학과 03반과 합반
    • 약물전달학

      • 학수번호 36213분반 01
      • 5학년 ( 1.5학점 , 1.5시간) 수 4~4
      • 전공필수,영어강의 팀티칭(1~43번)
    • 약물전달학

      • 학수번호 36213분반 02
      • 5학년 ( 1.5학점 , 1.5시간) 목 3~3
      • 전공필수,영어강의 팀티칭(44~86번)
    • 약물전달학

      • 학수번호 36213분반 03
      • 5학년 ( 1.5학점 , 1.5시간) 수 2~2
      • 전공필수,영어강의 팀티칭(87~130)
    • 나노의약품및제형개발

      • 학수번호 G16896분반 01
      • 학년 ( 3학점 , 3시간) 화 6~7 (약)
      • 영어강의
학력

한국과학기술원 Ph.D.(생명과학)

Columbia University M.S.(Engin. & Appl. Sci.)

Johns Hopkins University B.S.(Biomedical Engin.)

경력

Massachusetts Institute of Technology, Post-doc. 2010-03-01 ~ 2012-02-29

연구분야
Advanced Biomaterials and Drug Delivery
We are interested in developing novel biomaterials for drug delivery and tissue engineering. Some of the projects that we are most interested in are

1. Sustained release of protein drugs,
2. Novel regio-specific PEGylation for therapeutic proteins,
3. Natural polymer based hydrogels for cell therapy and drug delivery.
4. Preparation of Induced Pluripotent Stem (IPS) cells by non-viral gene delivery systems

It is important that our materials are designed to be non-cytotoxic, non-immunogenic, and biodegradable.
NanoBio and Theragnosis Technology
We are developing multi-functional nanoparticles for various applications. Drug, imaging, or biosensor molecules are incorporated within our nanoparticles. We aim to develop Nanobiotechnolgy that can efficiently and safely target particular tissues and organs to give therapeutic effects

1. Gene Delivery System (pDNA, mRNA, and siRNA delivery)
2. Anti-Cancer Drug Delivery System (water insoluble small molecule delivery)
3. Molecular Imaging System (ROS sensing, ECM degrading enzyme sensitive imaging probe)
4. Inorganic nanoparticles for biomedical sensors and probes
Nucleic Acid Nanotechnology
We are motivated by the potential of DNA Nanotechnology to improve the fields of drug delivery. Not only the structural interests of DNA nano-assembly, we want to move forward to apply this novel materials and approaches to treat various diseases. Of particular interest to us is the targeting of cancer and stem cells

1. Programmable Self-assembly of DNA/RNA Nanoparticles
2. Self-replicating Nucleic Acid Nanoparticles
3. Screening of Targeting Ligands as well as evaluating Cell Penetrating Peptides
4. Dip-pen Nano-lithography using DNA/RNA molecular ink