김병식(金炳植) 부교수

식품생명공학과

김병식 프로필 사진
김병식 교수는 엘텍공대 식품공학전공 소속으로 서울대학교 농생명공학부에서 식품미생물 안전성독성학을 전공했다. 학위과정 중 시애틀 워싱턴 대학교를 방문해 미생물 상호작용을 공부했고, 학위 후에는 시카고 노스웨스턴 대학 의대에서 Research Associate로 재직하며 세균 단백질 독소의 작용기전과 미생물-숙주 상호작용을 연구했다. 이후 한국생명공학연구원에서 세포생물학/면역학/단백질 구조적 측면에서 세균 독소에 관한 융합연구를 수행했다. 주된 연구관심분야는 미생물 상호작용, 박테리오파지, 미생물 단백질 독소, 독성인자 발현 조절 등이며, 이를통해 식품안전성을 확보하고 마이크로바이옴을 개선하는 방법을 탐구 중이다.
  • 아산공학관 429호
  • 02-3277-4031
  • 면담 가능시간
    • 월요일 10:00 - 12:00 / 금요일 10:00-12:00
  • 연구관심분야
    • Food Safety / Foodborne pathogens, Bacteriophage, Virulence factors, Microbiome / Food Pathobiome, Bacterial protein toxins
연구실적
  • [학술지논문] Pathogenic potential assessment of the Shiga toxin–producing Escherichia coli by a source attribution–considered machine learning model PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, v.118 no.20 , 2018877118-2018877118
    SCI
  • Exploring the Feasibility of 16S rRNA Short Amplicon Sequencing-Based Microbiota Analysis for Microbiological Safety Assessment of Raw Oyster Journal of microbiology and biotechnology, 2023, v.33 no.9, 1162-1169
    Scopus dColl.
  • Integrated-Omics Study on the Transcriptomic and Metabolic Changes of Bacillus licheniformis, a Main Microorganism of Fermented Soybeans, According to Alkaline pH and Osmotic Stress Journal of agricultural and food chemistry, 2023, v.71 no.39, 14379-14389
    SCIE Scopus dColl.
  • Multilayer Engineering of an Escherichia coli-Based Biotransformation System to Exclusively Produce Glycolic Acid from Formaldehyde ACS Sustainable Chemistry and Engineering, 2023, v.11 no.3, 1078-1086
    SCIE Scopus dColl.
  • Phage biocontrol of zoonotic food-borne pathogen Vibrio parahaemolyticus for seafood safety Food Control, 2023, v.144, 109334
    SCIE Scopus dColl.
  • Screening of Anti-Adhesion Agents for Pathogenic Escherichia coli O157:H7 by Targeting the GrlA Activator Journal of microbiology and biotechnology, 2023, v.33 no.3, 329-338
    SCIE Scopus KCI dColl.
  • Vibrio-infecting bacteriophages and their potential to control biofilm Food Science and Biotechnology, 2023, v.32 no.12, 1719-1727
    SCIE Scopus KCI dColl.
  • MARTX toxin of Vibrio vulnificus induces RBC phosphatidylserine exposure that can contribute to thrombosis Nature Communications, 2022, v.13 no.1, 4846
    SCIE Scopus dColl.
  • Vibrio vulnificus PlpA facilitates necrotic host cell death induced by the pore forming MARTX toxin Journal of Microbiology, 2022, v.60 no.2, 224-233
    SCIE Scopus KCI dColl.
  • Pathogenic potential assessment of the Shiga toxin-producing Escherichia coli by a source attribution-considered machine learning model Proceedings of the National Academy of Sciences of the United States of America, 2021, v.118 no.20, e2018877118
    SCIE Scopus dColl.
  • Reduced virulence of the MARTX toxin increases the persistence of outbreak-associated Vibrio vulnificus in host reservoirs JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, v.296, 100777
    SCIE Scopus dColl.
  • Tackling Vibrio parahaemolyticus in ready-to-eat raw fish flesh slices using lytic phage VPT02 isolated from market oyster Food Research International, 2021, v.150, 110779
    SCIE Scopus dColl.
  • A MARTX Toxin rtxA Gene Is Controlled by Host Environmental Signals through a CRP-Coordinated Regulatory Network in Vibrio vulnificus mBio, 2020, v.11 no.4
    SCIE Scopus dColl.
  • MARTX Toxin-Stimulated Interplay between Human Cells and Vibrio vulnificus mSphere, 2020, v.5 no.4, 0
    SCIE Scopus dColl.
  • Spatiotemporal Regulation ofVibrioExotoxins by HlyU and Other Transcriptional Regulators TOXINS, 2020, v.12 no.9, 544
    SCIE Scopus dColl.
  • Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, v.116 no.36, 18031-18040
    SCIE Scopus dColl.
  • Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species Scientific Reports, 2019, v.9 no.1, 4346
    SCIE Scopus dColl.
  • QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species MBIO, 2018, v.9 no.1, e02262-17
    SCIE Scopus dColl.
  • Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogen Vibrio vulnificus JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, v.293 no.47, 18110-18122
    SCIE Scopus dColl.
  • The modes of action of MARTX toxin effector domains Toxins, 2018, v.10 no.12, 507
    SCIE Scopus dColl.
  • Identification and characterization of Vibrio vulnificus plpA encoding a phospholipase A(2) essential for pathogenesis JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, v.292 no.41, 17129-17143
    SCIE Scopus dColl.
  • Variable Virulence of Biotype 3 Vibrio vulnificus due to MARTX Toxin Effector Domain Composition MSPHERE, 2017, v.2 no.4, e00272-17
    SCIE Scopus dColl.
  • MARTX effector cross kingdom activation by Golgi-associated ADP-ribosylation factors CELLULAR MICROBIOLOGY, 2016, v.18 no.8, 1078-1093
    SCIE Scopus dColl.
  • [학술지논문] Bacteriophages PECP14, PECP20, and their endolysins as effective biocontrol agents for Escherichia coli O157:H7 and other foodborne pathogens INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2024, v.409 no.409 , 110460-110460
    SCIE
  • [학술지논문] Lactoferrin-polyphenol composite nanocoating with enhanced chemical stability and cell-compatibility PROGRESS IN ORGANIC COATINGS, 2024, v.187 no.187 , 108099-108099
    SCIE
  • [학술지논문] Vibrio-infecting bacteriophages and their potential to control biofilm FOOD SCIENCE AND BIOTECHNOLOGY, 2023, v.32 no.12 , 1719-1727
    SCIE
  • [학술지논문] An archaeal transcription factor EnfR with a novel ‘eighth note’ fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1 NUCLEIC ACIDS RESEARCH, 2023, v.51 no.18 , 10026-10040
    SCIE
  • [학술지논문] Bacterial Sialic Acid Catabolism at the Host-Microbe Interface JOURNAL OF MICROBIOLOGY, 2023, v.61 no.4 , 369-377
    SCIE
  • [학술지논문] Exploring the Feasibility of 16S rRNA Short Amplicon Sequencing-Based Microbiota Analysis for Microbiological Safety Assessment of Raw Oyster JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2023, v.33 no.9 , 1162-1169
    SCIE
  • [학술지논문] Integrated-Omics Study on the Transcriptomic and Metabolic Changes of Bacillus licheniformis, a Main Microorganism of Fermented Soybeans, According to Alkaline pH and Osmotic Stress JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, v.71 no.39 , 14379-14389
    SCIE
  • [학술지논문] Multilayer Engineering of an Escherichia coli-Based Biotransformation System to Exclusively Produce Glycolic Acid from Formaldehyde ACS Sustainable Chemistry and Engineering, 2023, v.11 no.3 , 1078-1086
    SCIE
  • [학술지논문] Phage biocontrol of zoonotic food-borne pathogen Vibrio parahaemolyticus for seafood safety FOOD CONTROL, 2023, v.144 no.0 , 109334-109334
    SCIE
  • [학술지논문] Screening of Anti-Adhesion Agents for Pathogenic Escherichia coli O157:H7 by Targeting the GrlA Activator JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2023, v.33 no.3 , 329-338
    SCIE
  • [학술지논문] MARTX toxin of Vibrio vulnificus induces RBC phosphatidylserine exposure that can contribute to thrombosis NATURE COMMUNICATIONS, 2022, v.13 no.1 , 4846-4846
    SCI
  • [학술지논문] Vibrio vulnificus PlpA facilitates necrotic host cell death induced by the pore forming MARTX toxin JOURNAL OF MICROBIOLOGY, 2022, v.60 no.2 , 224-233
    SCIE
  • [학술지논문] Reduced virulence of the MARTX toxin increases the persistence of outbreak-associated Vibrio vulnificus in host reservoirs JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, v.296 no.0 , 100777-100777
    SCI
  • [학술지논문] Tackling Vibrio parahaemolyticus in ready-to-eat raw fish flesh slices using lytic phage VPT02 isolated from market oyster FOOD RESEARCH INTERNATIONAL, 2021, v.150 no.0 , 110779-110779
    SCI
  • [학술지논문] A MARTX Toxin rtxA Gene Is Controlled by Host Environmental Signals through a CRP-Coordinated Regulatory Network in Vibrio vulnificus MBIO, 2020, v.11 no.4 , 72320-72320
    SCIE
  • [학술지논문] MARTX Toxin-Stimulated Interplay between Human Cells and Vibrio vulnificus MSPHERE, 2020, v.5 no.4 , 65920-65920
    SCIE
  • [학술지논문] Spatiotemporal Regulation ofVibrioExotoxins by HlyU and Other Transcriptional Regulators TOXINS, 2020, v.12 no.9 , 544-544
    SCIE
  • [학술지논문] Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, v.116 no.36 , 18031-18040
    SCI
  • [학술지논문] Small-molecule inhibitor of HIyU attenuates virulence of Vibrio species SCIENTIFIC REPORTS, 2019, v.9 no.0 , 4346-4346
    SCI
  • [학술지논문] QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species MBIO, 2018, v.9 no.1 , 02262-0226217
    SCIE
  • [학술지논문] Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogen Vibrio vulnificus JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, v.293 no.47 , 18110-18122
    SCI
  • [학술지논문] The Modes of Action of MARTX Toxin Effector Domains TOXINS, 2018, v.10 no.12 , 5071-5071
    SCIE
  • [학술지논문] Identification and characterization of Vibrio vulnificus plpA encoding a phospholipase A(2) essential for pathogenesis JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, v.292 no.41 , 17129-17143
    SCI
  • [학술지논문] Variable Virulence of Biotype 3 Vibrio vulnificus due to MARTX Toxin Effector Domain Composition MSPHERE, 2017, v.2 no.4 , 00272-0027217
    SCIE
  • [학술지논문] MARTX effector cross kingdom activation by Golgi-associated ADP-ribosylation factors CELLULAR MICROBIOLOGY, 2016, v.18 no.8 , 1078-1093
    SCI
  • [학술지논문] Distinct Roles of the Repeat-Containing Regions and Effector Domains of the Vibrio vulnificus Multifunctional-Autoprocessing Repeats-in-Toxin (MARTX) Toxin MBIO, 2015, v.6 no.2 , 0032415-0032415
    SCIE
  • [학술지논문] Structural insights into the regulation of sialic acid catabolism by the Vibrio vulnificus transcriptional repressor NanR. Proceedings of the National Academy of Sciences of the United States of America, 2013, v.110 no.30 , 2829-2837
    SCI
  • [학술지논문] Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, v.109 no.41 , E2823-E2831
    SCI
  • [학술지논문] Cooperative regulation of the Vibrio vulnificus nan gene cluster by NanR protein, cAMP receptor protein, and N-acetylmannosamine 6-phosphate. Journal of Biological Chemistry, 2011, v.286 no.47 , 40889-40899
    SCI
  • [학술지논문] Identification and Characterization of a Novel Serine Protease, VvpS, That Contains Two Functional Domains and Is Essential for Autolysis of Vibrio vulnificus. JOURNAL OF BACTERIOLOGY, 2011, v.193 no.15 , 3722-3732
    SCI
  • [학술지논문] Crystal Structure of SmcR, a Quorum-sensing Master Regulator of Vibrio vulnificus, Provides Insight into Its Regulation of Transcription. JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, v.285 no.18 , 14020-14030
    SCI
  • [학술지논문] The Capability of Catabolic Utilization of N-Acetylneuraminic Acid, a Sialic Acid, Is Essential for Vibrio vulnificus Pathogenesis. INFECTION AND IMMUNITY, 2009, v.77 no.8 , 3209-3217
    SCI
  • [학술지논문] Vibrio Vulnificus rtxE is important for virulence, and its expression is induced by exposure to host cells. INFECTION AND IMMUNITY, 2008, v.76 no.4 , 1509-1517
    SCI
  • [학술지논문] Identification and characterization of the Vibrio vulnificus rtxA essential for cytotoxicity in vitro and virulence in mice. JOURNAL OF MICROBIOLOGY, 2007, v.45 no.2 , 146-152
    SCIE
강의
  • 2023-2학기

    • 식품미생물실험

      • 학수번호 36314분반 01
      • 2학년 ( 3학점 , 4.5시간) 월 5~5 (공학A102) , 월 6~7 (공학)
      • 영어강의 선수학습사항: 식품미생물학 (36311)
    • 미생물단백질독소학

      • 학수번호 G18317분반 01
      • 학년 ( 3학점 , 3시간) 월 2~3 (공학)
  • 2023-1학기

    • 식품미생물학

      • 학수번호 36311분반 01
      • 2학년 ( 3학점 , 3시간) 수 3~3 (공학A102) , 금 2~2 (공학A102)
      • 영어강의
    • 식품미생물유전체학 강의 계획서 상세보기

      • 학수번호 38771분반 01
      • 4학년 ( 3학점 , 3시간) 화 3~3 (공학) , 목 2~2 (158)
    • 식품위해미생물특론

      • 학수번호 G18318분반 01
      • 학년 ( 3학점 , 3시간) 월 4~5 (공학)
  • 2022-2학기

    • 식품미생물실험

      • 학수번호 36314분반 01
      • 2학년 ( 3학점 , 4.5시간) 월 5~5 (공학A102) , 월 6~7 (공학)
      • 영어강의
    • 미생물분자생물학특론

      • 학수번호 G18314분반 01
      • 학년 ( 3학점 , 3시간) 화 6~7 (공학)
  • 2022-1학기

    • 식품미생물학

      • 학수번호 36311분반 01
      • 2학년 ( 3학점 , 3시간) 화 4~4 , 금 5~5
      • 영어강의
    • 식품발효및미생물유전체학

      • 학수번호 36330분반 01
      • 4학년 ( 3학점 , 3시간) 수 2~3 (공학)
    • 식품위해미생물특론

      • 학수번호 G18318분반 01
      • 학년 ( 3학점 , 3시간) 화 2~3
  • 2021-2학기

    • 식품미생물실험

      • 학수번호 36314분반 01
      • 2학년 ( 3학점 , 4.5시간) 화 5~5 (공학) , 화 6~7 (152)
      • 영어강의
    • 식품과학기초

      • 학수번호 38414분반 01
      • 1학년 ( 1학점 , 1시간) 월 2~2
    • 미생물분자생물학특론

      • 학수번호 G16808분반 01
      • 학년 ( 3학점 , 3시간) 화 2~3 (공학)
  • 2021-1학기

    • 식품미생물학

      • 학수번호 36311분반 01
      • 2학년 ( 3학점 , 3시간) 월 5~5 , 수 4~4
      • 영어강의
    • 식품발효및미생물유전체학

      • 학수번호 36330분반 01
      • 4학년 ( 3학점 , 3시간) 수 6~7 (공학)
    • 식품위해미생물특론

      • 학수번호 G17621분반 01
      • 학년 ( 3학점 , 3시간) 화 6~7 (공학)
학력

서울대학교 농학박사(농생명공학부)

서울대학교 농학사(식품동물생명공학부)

경력

한국생명공학연구원 2016-04-01 ~ 2018-02-28

Northwestern University 2012-10-01 ~ 2016-02-29

서울대학교 2012-03-01 ~ 2012-08-31

University of Washington 2009-10-01 ~ 2010-09-30