김광명(金光明) 교수

약학과[대학원] /약학부 /제약산업학과[대학원]

김광명 프로필 사진
김광명 교수는 약학대학(원) 약학과 소속으로 난치성 질환의 진단 및 치료용 나노메디슨에 대한 연구를 진행하고 있다. 성균관대학교 및 광주과학기술원에서 각각 학사 및 석/박사 학위를 취득하였으며, 이후 한국과학기술연구원에 재직하여 악성 종양 등 난치성 질환의 미세 환경 특이적 진단 및 선택적 약물 전달, 나아가 면역 활성화를 통한 치료 효과 증진을 위한 고기능성 나노메디슨의 개발을 위하여 연구하였다. 이를 통해 Advanced Materials, Advanced Functional Materials, ACS Nano, Angewandte Chemie, JACS 등 국제 유명 학술지를 포함하여 약 300 편 이상의 논문을 발표하였으며, 5 년 연속으로 톰슨 로이터가 주관하는 피인용 횟수 상위 1% 연구자에 선정되는 등 우수한 연구 성과를 기록하였다. 2022년 이화여자대학교 약학과로 부임, 높은 수준의 연구 인프라를 기반으로 다양한 나노메디슨 후보물질의 발굴/합성 뿐만 아니라 세포 및 생체 내 평가, 전임상 연구까지 폭넓은 연구를 진행 중에 있다.
  • 산학협력관 523-3호
  • 02-3277-2466
  • 연구관심분야
    • 진단치료, 나노메디슨, 약물 전구체, 면역치료
연구실적
  • Accurately Controlled Tumor Temperature with Silica-Coated Gold Nanorods for Optimal Immune Checkpoint Blockade Therapy BIOMATERIALS RESEARCH, 2024, v.28, 24
    SCIE KCI dColl.
  • Cancer cell-specific and pro-apoptotic SMAC peptide-doxorubicin conjugated prodrug encapsulated aposomes for synergistic cancer immunotherapy Journal of Nanobiotechnology, 2024, v.22 no.1, 109
    SCIE Scopus dColl.
  • Implantable MicroLED-Mediated Chemo-Photodynamic Combination Therapy for Glioma Treatment Advanced Functional Materials, 2024, v.34 no.30, 2316386
    SCIE Scopus dColl.
  • Mucoadhesive Mesalamine Prodrug Nanoassemblies to Target Intestinal Macrophages for the Treatment of Inflammatory Bowel Disease ACS Nano, 2024, v.18 no.25, 16297-16311
    SCIE Scopus dColl.
  • Multi-functional nanomedicines for combinational cancer immunotherapy that transform cold tumors to hot tumors EXPERT OPINION ON DRUG DELIVERY, 2024, v.21 no.4, 627-638
    SCIE Scopus dColl.
  • Nano-Delivery of Immunogenic Cell Death Inducers and Immune Checkpoint Blockade Agents: Single-Nanostructure Strategies for Enhancing Immunotherapy Pharmaceutics, 2024, v.16 no.6, 795
    SCIE Scopus dColl.
  • Photo-induced crosslinked and anti-PD-L1 peptide incorporated liposomes to promote PD-L1 multivalent binding for effective immune checkpoint blockade therapy Acta Pharmaceutica Sinica B, 2024, v.14 no.3, 1428-1440
    SCIE Scopus dColl.
  • Recent developments in chemodrug-loaded nanomedicines and their application in combination cancer immunotherapy Journal of Pharmaceutical Investigation, 2024, v.54 no.1, 13-36
    SCIE Scopus KCI dColl.
  • Adoptive Transfer of Photosensitizer-Loaded Cytotoxic T Cells for Combinational Photodynamic Therapy and Cancer Immuno-Therapy Pharmaceutics, 2023, v.15 no.4, 1295
    SCIE Scopus dColl.
  • All-in-one glycol chitosan nanoparticles for co-delivery of doxorubicin and anti-PD-L1 peptide in cancer immunotherapy Bioactive Materials, 2023, v.28, 358-375
    SCIE Scopus dColl.
  • Cancer-Specific Delivery of Proteolysis-Targeting Chimeras (PROTACs) and Their Application to Cancer Immunotherapy PHARMACEUTICS, 2023, v.15 no.2, 411
    SCIE Scopus dColl.
  • Enhanced delivery of the phototherapeutic nanoparticles via hepatocyte overload Colloids and Surfaces B: Biointerfaces, 2023, v.221, 112959
    SCIE Scopus dColl.
  • Fluorescence-Based Mono- and Multimodal Imaging for In Vivo Tracking of Mesenchymal Stem Cells Biomolecules, 2023, v.13 no.12, 1787
    SCIE Scopus dColl.
  • In situ albumin-binding and esterase-specifically cleaved BRD4-degrading PROTAC for targeted cancer therapy Biomaterials, 2023, v.295, 122038
    SCIE Scopus dColl.
  • In vivo toxicity evaluation of tumor targeted glycol chitosan nanoparticles in healthy mice: repeated high-dose of glycol chitosan nanoparticles potentially induce cardiotoxicity JOURNAL OF NANOBIOTECHNOLOGY, 2023, v.21 no.1, 82
    SCIE Scopus dColl.
  • Intracellular Glucose-Depriving Polymer Micelles for Antiglycolytic Cancer Treatment Advanced Materials, 2023, v.35 no.10, 2207342
    SCIE Scopus dColl.
  • Micro-syringe chip-guided intratumoral administration of lipid nanoparticles for targeted anticancer therapy Biomaterials Research, 2023, v.27 no.1, 102
    Scopus dColl.
  • Perspectives for Improving the Tumor Targeting of Nanomedicine via the EPR Effect in Clinical Tumors International Journal of Molecular Sciences, 2023, v.24 no.12, 10082
    SCIE Scopus dColl.
  • Recent Studies and Progress in the Intratumoral Administration of Nano-Sized Drug Delivery Systems Nanomaterials, 2023, v.13 no.15, 2225
    SCIE Scopus dColl.
  • Thermally Managed, Injectable Optoelectronic Probe with Heat Dissipation Guide for Photodynamic Therapy Small, 2023, v.19 no.35, 2300753
    SCIE Scopus dColl.
  • Comparative study of cathepsin B-cleavable linkers for the optimal design of cathepsin B-specific doxorubicin prodrug nanoparticles for targeted cancer therapy Biomaterials, 2022, v.289, 121806
    SCIE Scopus dColl.
  • Implantable micro-scale LED device guided photodynamic therapy to potentiate antitumor immunity with mild visible light Biomaterials Research, 2022, v.26 no.1, 56
    Scopus dColl.
  • Injectable Hydrogel-Based Combination Cancer Immunotherapy for Overcoming Localized Therapeutic Efficacy Pharmaceutics, 2022, v.14 no.9, 1908
    SCIE Scopus dColl.
  • Liposome-mediated PD-L1 multivalent binding promotes the lysosomal degradation of PD-L1 for T cell-mediated antitumor immunity Biomaterials, 2022, v.290, 121841
    SCIE Scopus dColl.
  • Mesenchymal Stem Cell-Mediated Deep Tumor Delivery of Gold Nanorod for Photothermal Therapy Nanomaterials, 2022, v.12 no.19, 3410
    SCIE Scopus dColl.
  • Molecularly engineered siRNA conjugates for tumor-targeted RNAi therapy Journal of Controlled Release, 2022, v.351, 713-726
    SCIE Scopus dColl.
  • Preclinical development of carrier-free prodrug nanoparticles for enhanced antitumor therapeutic potential with less toxicity Journal of Nanobiotechnology, 2022, v.20 no.1, 436
    SCIE Scopus dColl.
  • Prediction the clinical EPR effect of nanoparticles in patient-derived xenograft models Journal of Controlled Release, 2022, v.351, 37-49
    SCIE Scopus dColl.
  • Tumor-Specific Monomethyl Auristatin E (MMAE) Prodrug Nanoparticles for Safe and Effective Chemotherapy PHARMACEUTICS, 2022, v.14 no.10, 2131
    SCIE Scopus dColl.
  • [학술지논문] Thermally Managed, Injectable Optoelectronic Probe with Heat Dissipation Guide for Photodynamic Therapy SMALL, 2023, v.19 no.35 , 202300-202300
    SCIE
  • [학술지논문] Comparative study of cathepsin B-cleavable linkers for the optimal design of cathepsin B-specific doxorubicin prodrug nanoparticles for targeted cancer therapy BIOMATERIALS, 2022, v.289 no.0 , 121806-121806
    SCI
  • [학술지논문] Copper-Free Click Chemistry: Applications in Drug Delivery, Cell Tracking, and Tissue Engineering ADVANCED MATERIALS, 2022, v.34 no.10 , 2107192--
    SCI
  • [학술지논문] Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment ADVANCED DRUG DELIVERY REVIEWS, 2022, v.186 no.- , 114344--
    SCI
  • [학술지논문] Liposome-mediated PD-L1 multivalent binding promotes the lysosomal degradation of PD-L1 for T cell-mediated antitumor immunity BIOMATERIALS, 2022, v.290 no.0 , 121841-121841
    SCI
  • [학술지논문] Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery ADVANCED DRUG DELIVERY REVIEWS, 2022, v.183 no.- , 114177--
    SCI
  • [학술지논문] Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity BIOMATERIALS, 2021, v.272 no.- , 120791--
    SCI
  • [학술지논문] Predicting in vivo therapeutic efficacy of bioorthogonally labeled endothelial progenitor cells in hind limb ischemia models via non-invasive fluorescence molecular tomography BIOMATERIALS, 2021, v.266 no.- , 120472--
    SCI
  • [학술지논문] The safe and effective intraperitoneal chemotherapy with cathepsin B-specific doxorubicin prodrug nanoparticles in ovarian cancer with peritoneal carcinomatosis Biomaterials, 2021, v.279 no.- , 121189--
    SCI
  • [학술지논문] Visible-Light-Triggered Prodrug Nanoparticles Combine Chemotherapy and Photodynamic Therapy to Potentiate Checkpoint Blockade Cancer Immunotherapy ACS NANO, 2021, v.15 no.7 , 12086-12098
    SCI
강의
  • 2024-2학기

    • 심화실습및연구Ⅰ

      • 학수번호 37154분반 01
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅱ

      • 학수번호 37155분반 01
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅲ

      • 학수번호 37156분반 01
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
  • 2024-1학기

    • 약물전달학

      • 학수번호 36213분반 01
      • 5학년 ( 1.5학점 , 1.5시간) 목 4~4 (포552)
      • 전공필수,영어강의 학번 1~40
    • 약물전달학

      • 학수번호 36213분반 02
      • 5학년 ( 1.5학점 , 1.5시간) 목 5~5 (포552)
      • 전공필수,영어강의 학번 41~80
    • 약물전달학

      • 학수번호 36213분반 03
      • 5학년 ( 1.5학점 , 1.5시간) 수 5~5 (약A400)
      • 전공필수,영어강의 학번 81~120
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
    • 약학연구입문

      • 학수번호 38940분반 01
      • 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약A404)
      • 전공필수
    • 약물전달시스템

      • 학수번호 G16857분반 01
      • 학년 ( 3학점 , 3시간) 월 5~6 (약)
  • 2023-2학기

  • 2023-1학기

    • 약물전달학

      • 학수번호 36213분반 01
      • 5학년 ( 1.5학점 , 1.5시간) 목 4~4 (포552)
      • 전공필수,영어강의 학번 1~43
    • 약물전달학

      • 학수번호 36213분반 02
      • 5학년 ( 1.5학점 , 1.5시간) 목 3~3 (포552)
      • 전공필수,영어강의 학번 44~86
    • 약물전달학

      • 학수번호 36213분반 03
      • 5학년 ( 1.5학점 , 1.5시간) 수 4~4 (약A400)
      • 전공필수,영어강의 학번 87~130. 산업제약학과 04반과 합반
    • 약물전달학

      • 학수번호 36213분반 04
      • 5학년 ( 1.5학점 , 1.5시간) 수 4~4 (약A400)
      • 전공필수,영어강의 약학과 03반과 합반
    • 산업약학입문 강의 계획서 상세보기

      • 학수번호 39045분반 01
      • 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약)
    • 약물전달시스템

      • 학수번호 G16857분반 01
      • 학년 ( 3학점 , 3시간) 월 5~6 (약)
  • 2022-2학기

    • 신약개발세미나및실습IV

      • 학수번호 G16889분반 01
      • 학년 ( 3학점 , 3시간) 목 7~8 (약A400)
      • 교수결정
    • 신약개발세미나및실습Ⅳ

      • 학수번호 G18241분반 01
      • 학년 ( 3학점 , 3시간) 목 7~8 (약A400)
      • 교수결정