정병문 교수는 이화여자대학교 화학·나노과학전공/분자생명과학부 소속 교수로 고분자생체재료를 연구하는 과학자이다. 서울대 화학과에서 학사, KAIST 화학과에서 석사, 및 미국 유타대 약제학 및 약제화학 대학원에서 박사학위를 받았으며, 새로운 생체재료 및 자극감응성 하이드로젤을 발굴하고 이들을 의약전달시스템, 3차원 세포배양, 그리고 조직공학 등 의학적 응용에 대한 연구를 진행하고 있다. 한국생체재료학회 부회장겸 학회 공식 논문인 Biomaterials Research의 편집위원장을 역임했으며, 한국고분자학회 평의원등으로 활동하고 있다. 현재까지 총 160 여편의 논문을 <Nature>, <Advanced Materials>, <Advanced Functional Materials>, <Biomaterials>, <J. Controlled Release>, <Macromolecules>등 SCI급 국제학술지에 발표하였다.
고분자 생체재료, 의약전달시스템, 3차원 세포배양 및 조직공학, 하이드로젤, 자극민감성 고분자
연구실적
Tyr-Tyr-Glu Tripeptide for Regeneration of Articular Cartilage through Chondrogenic Differentiation of Mesenchymal Stem CellsBIOMATERIALS RESEARCH, 2025, v.29, 272
Pralatrexate Sustainably Released from Polypeptide Thermogel Is Effective for Chondrogenic Differentiation of Mesenchymal Stem CellsACS Applied Materials and Interfaces, 2022, v.14 no.3, 3773-3783
2D and 3D Hybrid Systems for Enhancement of Chondrogenic Differentiation of Tonsil-Derived Mesenchymal Stem CellsAdvanced Functional Materials, 2015, v.25 no.17, 2573-2582
Complexation-induced biomimetic long range fibrous orientation in a rigid-flexible block copolymer thermogelAdvanced Functional Materials, 2012, v.22 no.24, 5118-5125
[학술지논문] Copper (II) complexes derived from 3, 5-dibromosalicylaldehyde semicarbazone: Crystal structures, spectra and in vitro cytotoxicity studiesPOLYHEDRON, 2026, v.289no.1, 118002-118002
SCIE
[학술지논문] Poly(dl-Alanine-co-Glycine): Peptide Analogue of Poly(dl-Lactide-co-Glycolide)BIOMACROMOLECULES, 2025, v.26no.11, 7923-7929
SCIE
[학술지논문] Tyr-Tyr-Glu Tripeptide for Regeneration of Articular Cartilage through Chondrogenic Differentiation of Mesenchymal Stem CellsBIOMATERIALS RESEARCH, 2025, v.29no.0, 272-272
SCIE
[학술지논문] Low-Molecular-Weight PEGs for Cryopreservation of Stem Cell SpheroidsBIOMATERIALS RESEARCH, 2024, v.28no.37, 1-11
SCIE
[학술지논문] Poly(L-threonine-co-l-threonine Succinate) Thermogels for Sustained Release of LixisenatideBIOMACROMOLECULES, 2024, v.25no.8, 4946-4955
[학술지논문] Drug-Releasing Thermogel for Osteoarthritis Induction in an Animal ModelBIOMACROMOLECULES, 2023, v.24no.12, 6025-6031
SCIE
[학술지논문] Oligonucleotides as Inhibitors of Ice RecrystallizationBIOMACROMOLECULES, 2023, v.24no.5, 2118-2126
SCIE
[학술지논문] Poly(l-alanine-co-l-threonine succinate) as a Biomimetic CryoprotectantACS APPLIED MATERIALS & INTERFACES, 2023, v.15no.50, 58092-58102
SCIE
[학술지논문] Rediscovery of poly(ethylene glycol)s as a cryoprotectant for mesenchymal stem cellsBIOMATERIALS RESEARCH, 2023, v.27no.1, 17-17
SCIE
[학술지논문] DL-Polyalanine as a PEG-Free ThermogelACS MACRO LETTERS, 2022, v.11no.6, 825-829
SCI
[학술지논문] Folic acid pretreatment and its sustained delivery for chondrogenic differentiation of MSCsJOURNAL OF CONTROLLED RELEASE, 2022, v.343no.3, 118-130
SCI
[학술지논문] Hyaluronic acid-g-PPG and PEG-PPG-PEG hybrid thermogel for prolonged gel stability and sustained drug releaseCARBOHYDRATE POLYMERS, 2022, v.291no.5, 119559-119569
[학술지논문] Poly(L-alanine-co-L-lysine)-g-Trehalose as a Biomimetic Cryoprotectant for Stem CellsBIOMACROMOLECULES, 2022, v.23no.5, 1995-2006
SCI
[학술지논문] Pralatrexate Sustainably Released from Polypeptide Thermogel Is Effective for Chondrogenic Differentiation of Mesenchymal Stem CellsACS APPLIED MATERIALS & INTERFACES, 2022, v.14no.3, 3773-3783
[학술지논문] Size and Shape Control of Ice Crystals by Amphiphilic Block Copolymers and Their Implication in the Cryoprotection of Mesenchymal Stem CellsACS APPLIED MATERIALS & INTERFACES, 2021, v.13no.29, 33969-33980
SCI
[학술지논문] Iron Ion-Releasing Polypeptide Thermogel for Neuronal Differentiation of Mesenchymal Stem CellsBIOMACROMOLECULES, 2020, v.21no.1, 143-151
[학술지논문] Thermogelling Inclusion Complex System for Fine-Tuned Osteochondral Differentiation of Mesenchymal Stem CellsBIOMACROMOLECULES, 2020, v.21no.8, 3176-3185
SCI
[학술지논문] Visible-Light Photocatalytic Conversion of Carbon Dioxide by Ni(II) Complexes with N4S2 Coordination: Highly Efficient and Selective Production of FormateJOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, v.142no.45, 19142-19149
SCI
[학술지논문] Polypeptide Thermogel-Filled Silk Tube as a Bioactive Nerve ConduitACS Applied Bio Materials, 2019, v.2no.5, 1967-1974
Scopus
[학술지논문] Tonsil-derived stem cells as a new source of adult stem cellsWORLD JOURNAL OF STEM CELLS, 2019, v.11no.8, 506-518
SCIE
[학술지논문] Coordinating Thermogel for Stem Cell Spheroids and Their Cyto-EffectivenessADVANCED FUNCTIONAL MATERIALS, 2018, v.28no.7, 00000-1706286
SCI
[학술지논문] Fast Degradable Polycaprolactone for Drug DeliveryBIOMACROMOLECULES, 2018, v.19no.6, 2302-2307
SCI
[학술지논문] Injectable thermogel for 3D culture of stem cellsBIOMATERIALS, 2018, v.159no.3, 91-107
SCI
[학술지논문] Chiro-Optical Modulation for NURR1 Production from Stem CellsACS CHEMICAL NEUROSCIENCE, 2017, v.8no.7, 1455-1458
SCIE
[학술지논문] Hepatogenic Supported Differentiation of Mesenchymal Stem Cells in a Lactobionic Acid-Conjugated ThermogelACS MACRO LETTERS, 2017, v.6no.11, 1305-1309
SCI
[학술지논문] Injectable Polypeptide Thermogel as a Tissue Engineering System for Hepatogenic Differentiation of Tonsil-Derived Mesenchymal Stem CellsACS APPLIED MATERIALS & INTERFACES, 2017, v.9no.13, 11568-11576
SCI
[학술지논문] Layered Double Hydroxide and Polypeptide Thermogel Nanocomposite System for Chondrogenic Differentiation of Stem CellsACS APPLIED MATERIALS & INTERFACES, 2017, v.9no.49, 42668-42675
SCI
[학술지논문] alpha,omega-Diphenylalanine-End-Capping of PEG-PPG-PEG Polymers Changes the Micelle Morphology and Enhances Stability of the ThermogelBIOMACROMOLECULES, 2017, v.18no.7, 2214-2219
SCI
[학술지논문] Composite System of Graphene Oxide and Polypeptide Thermogel As an Injectable 3D Scaffold for Adipogenic Differentiation of Tonsil-Derived Mesenchymal Stem CellsACS APPLIED MATERIALS INTERFACES, 2016, v.8no.8, 5160-5169
[학술지논문] Nanocomposite versus Mesocomposite for Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem CellsADVANCED HEALTHCARE MATERIALS, 2016, v.5no.3, 353-363
SCIE
[학술지논문] Structural sensitivity of peptoid-based low molecular mass organogelatorMATERIALS AND DESIGN, 2016, v.108no.10, 659-665
SCIE
[학술지논문] 2D and 3D Hybrid Systems for Enhancement of Chondrogenic Differentiation of Tonsil-Derived Mesenchymal Stem CellsADVANCED FUNCTIONAL MATERIALS, 2015, v.25no.17, 2573-2582
SCI
[학술지논문] Control of rhGH Release Profile from PEG-PAF ThermogelBIOMACROMOLECULES, 2015, v.16no.5, 1461-1469
SCI
[학술지논문] Microsphere-Incorporated Hybrid Thermogel for Neuronal Differentiation of Tonsil Derived Mesenchymal Stem CellsADVANCED HEALTHCARE MATERIALS, 2015, v.4no.10, 1565-1574
SCIE
[학술지논문] PEG-Poly(l-alanine) Thermogel As a 3D Scaffold of Bone-Marrow-Derived Mesenchymal Stem CellsMACROMOLECULAR BIOSCIENCE, 2015, v.15no.4, 464-472
[학술지논문] Temperature-sensitive polypeptide nanogels for intracellular delivery of a biomacromolecular drugJournal of Materials Chemistry B, 2015, v.3no.17, 3525-3530
SCI
[학술지논문] Tonsil-derived Mesenchymal Stem Cells Ameliorate CCl4-induced Liver Fibrosis in Mice via Autophagy ActivationSCIENTIFIC REPORTS, 2015, v.5no.1, 1-7
SCIE
[학술지논문] Topology effects on the LCST of end-capped poly(ethylene glycol)sBiomaterials and Biomedical Engineering, 2015, v.2no.1, 15-22
[학술지논문] 3D Culture of Tonsil-Derived Mesenchymal Stem Cells in Poly(ethylene glycol)-Poly(L-alanine-co-L-phenyl alanine) ThermogelADVANCED HEALTHCARE MATERIALS, 2014, v.3no.11, 1782-1791
[학술지논문] Differentiation of Tonsil-Tissue-Derived Mesenchymal Stem Cells Controlled by Surface-Functionalized Microspheres in PEG-Polypeptide ThermogelsBIOMACROMOLECULES, 2014, v.15no.0, 2180-2187
SCI
[학술지논문] Ion and Temperature Sensitive Polypeptide Block CopolymerBIOMACROMOLECULES, 2014, v.15no.10, 3664-3670
SCI
[학술지논문] Polypeptide Thermogels as a Three Dimensional Culture Scaffold for Hepatogenic Differentiation of Human Tonsil-Derived Mesenchymal Stem CellsACS APPLIED MATERIALS INTERFACES, 2014, v.6no.19, 17034-17043
SCI
[학술지논문] Thermal Gelation or Gel Melting: (Ethylene glycol)(113)-(L-alanine)(12) and (Ethylene glycol)(113)-(L-lactic acid)(12)JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2014, v.52no.17, 2434-2441
SCI
[학술지논문] 3D culture of adipose-tissue-derived stem cells mainly leads to chondrogenesis in poly(ethylene glycol)-poly(l-alanine) diblock copolymer thermogelBiomacromolecules 14
(9), 2013, v.14no.9, 3256-3266
Scopus
[학술지논문] Changes in nanoassembly of oligocaprolactone end-capped Pluronic F127 and the abnormal hydrophobicity trend of phase transitionMacromolecules, 2013, v.46no.10, 4215-4222
Scopus
[학술지논문] Incorporation of d-alanine into poly(ethylene glycol) and l-poly(alanine-co-phenylalanine) block copolymers affects their nanoassemblies and enzymatic degradationSoft Matter, 2013, v.9no.33, 8014-8022
Scopus
[학술지논문] Recent progress of in situ formed gels for biomedical applicationsProgress in Polymer Science, 2013, v.38no.3-4, 672-701
Scopus
[학술지논문] Biodegradable ThermogelsACCOUNTS OF CHEMICAL RESEARCH, 2012, v.45no.3, 424-433
SCI
[학술지논문] Cell Therapy for Skin Wound Using Fibroblast Encapsulated Poly(ethylene glycol)-poly(L-alanine) ThermogelBIOMACROMOLECULES, 2012, v.13no.4, 1106-1111
SCI
[학술지논문] Chondrocyte 3D-culture in RGD-modified crosslinked hydrogel with temperature-controllable modulusMACROMOLECULAR RESEARCH, 2012, v.20no.1, 106-111
SCI
[학술지논문] Complexation-Induced Biomimetic Long Range Fibrous Orientation in a Rigid-Flexible Block Copolymer ThermogelADVANCED FUNCTIONAL MATERIALS, 2012, v.22no.24, 5118-5125
SCI
[학술지논문] Molecular captain: A light-sensitive linker molecule in poly(ethylene glycol)-poly(L-alanine)-poly(ethylene glycol) triblock copolymer directs molecular nano-assembly, conformation, and sol-gel transitionJOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2012, v.50no.15, 3184-3191
SCI
[학술지논문] PEG-L-PAF and PEG-D-PAF: Comparative Study on Thermogellation and BiodegradationMACROMOLECULES, 2012, v.45no.4, 2007-2013
SCI
[학술지논문] Sol-gel transition of PEG-PAF aqueous solution and its application for hGH sustained releaseJOURNAL OF MATERIALS CHEMISTRY, 2012, v.22no.13, 6072-6079
SCI
[학술지논문] Temperature-responsive compounds as in situ gelling biomedical materialsCHEMICAL SOCIETY REVIEWS, 2012, v.41no.14, 4860-4883
SCI
[학술지논문] Thermogelling Chitosan-g-(PAF-PEG) Aqueous Solution As an Injectable ScaffoldBIOMACROMOLECULES, 2012, v.13no.6, 1750-1757
SCI
[학술지논문] Block sequence affects thermosensitivity and nano-assembly: PEG-L-PA-DL-PA and PEG-DL-PA-L-PA block copolymersSOFT MATTER, 2011, v.7no.14, 6515-6521
[학술지논문] Screening and Characterization of High-Affinity ssDNA Aptamers against Anthrax Protective AntigenJOURNAL OF BIOMOLECULAR SCREENING, 2011, v.16no.2, 266-271
SCI
[학술지논문] Synthesis and characterization of novel thermo-responsive F68 block copolymers with cell-adhesive RGD peptideJOURNAL OF COLLOID AND INTERFACE SCIENCE, 2011, v.360no.1, 78-85
SCI
[학술지논문] Thermal gelling polyalanine-poloxamine-polyalanine aqueous solution for chondrocytes 3D culture: Initial concentration effectSOFT MATTER, 2011, v.7no.2, 456-462
SCI
[학술지논문] Thermoreversible Radial Growth of Micellar Assembly for Hydrogel Formation Using Zwitterionic Oligopeptide CopolymerMACROMOLECULES, 2011, v.44no.7, 2269-2275
SCI
[학술지논문] pH/temperature sensitive chitosan-g-(PA-PEG) aqueous solutions as new thermogelling systemsJOURNAL OF MATERIALS CHEMISTRY, 2011, v.21no.14, 5484-5491
SCI
[학술지논문] Block length affects secondary structure, nanoassembly and thermosensitivity of poly(ethylene glycol)-poly(L-alanine) block copolymersJOURNAL OF MATERIALS CHEMISTRY, 2010, v.20, 3416-3421
SCI
[학술지논문] Comprehensive Analysis Reveals Dynamic and Evolutionary Plasticity of Rab GTPases and Membrane Traffic in Tetrahymena thermophilaPLOS GENETICS, 2010, v.6no.10, 1-18
SCI
[학술지논문] Fabrication and Electrochemical Application of Monolayers of Well-Ordered Macroporous SilicaJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2010, v.10, 158-162
SCI
[학술지논문] In situ thermal gelling polypeptide for chondrocytes 3D cultureBIOMATERIALS, 2010, v.31, 9266-9272
[학술지논문] Tripodal amphiphiles tunable for self-assembly to polymersomesJOURNAL OF CONTROLLED RELEASE, 2010, v.142, 132-137
SCI
[학술지논문] Characterization of a extreme thermostable fructose-1,6-bisphosphate aldolase from hyperthermophilic bacterium Aquifex aeolicusENZYME AND MICROBIAL TECHNOLOGY, 2009, v.45, 261-266
SCI
[학술지논문] End Groups Adjusting the Molecular Nano-Assembly Pattern and Thermal Gelation of Polypeptide Block Copolymer Aqueous SolutionMACROMOLECULES, 2009, v.42no.8, 3147-3151
SCI
[학술지논문] Enzymatically degradable temperature-sensitive polypeptide as a new in-situ gelling biomaterialJOURNAL OF CONTROLLED RELEASE, 2009, v.137, 25-30
SCI
[학술지논문] N-Methyl-D-Aspartate Receptor-Mediated Chemotaxis and Ca2+ Signaling in Tetrahymena pyriformisPROTIST, 2009, v.160no.2, 331-342
SCI
[학술지논문] PVPylated Poly(alanine) as a New Thermogelling PolymerMACROMOLECULES, 2009, v.42, 6710-6715
[학술지논문] The effect of polymer composition on the gelation behavior of PLGA-g-PEG biodegradable thermoreversible gelsJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2009, v.89Ano.1, 248-254
SCI
[학술지논문] A micellar prodrug of paclitaxel conjugated to cyclotriphosphazeneBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, v.18, 6410-6413
SCI
[학술지논문] Secondary Structure Effect of Polypeptide on Reverse Thermal Gelation and Degradation of L/DL-Poly(alanine)-Poloxamer-L/DL-Poly(alanine) CopolymersMACROMOLECULES, 2008, v.41, 8204-8209
SCI
[학술지논문] Significance of secondary structure in nanostructure formation and thermosensitivity of polypeptide block copolymersSOFT MATTER, 2008, v.4no.12, 2383-2387
SCI
[학술지논문] Solvent-free preparation of caprolactone oligomer microspheresJOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS, 2008, v.69no.5-6, 1596-1599
SCI
[학술지논문] Temperature-sensitive poly (caprolactone-co-trimethylene carbonate)-poly(ethylene glycol)-poly(caprolactone-co-trimethylene carbonate) as in situ gel-forming biomaterialMACROMOLECULES, 2008, v.41no.17, 6486-6492
SCI
[학술지논문] Vesicle-to-spherical micelle-to-tubular nanostructure transition of monomethoxy-poly(ethylene glycol)-poly(trimethylene carbonate) diblock copolymerJOURNAL OF PHYSICAL CHEMISTRY B, 2008, v.112no.25, 7420-7423
SCI
[학술지논문] Closed-loop sol-gel transition of PEG-PEC aqueous solutionJOURNAL OF PHYSICAL CHEMISTRY B, 2007, v.111no.27, 7715-7718
[학술지논문] Iron porphyrins anchored to a thermosensitive polymeric core-shell nanosphere as a thermotropic catalystCHEMICAL COMMUNICATIONS, 2005, v.75, 2960-2962
SCI
[학술지논문] New thermogelling poly (organophosphazenes) with methoxypoly(ethylene glycol) and oligopeptide as side groupsPOLYMER, 2005, v.46, 5075-5081
SCI
[학술지논문] Recyclable porphyrin catalyst with core-shell nanostructureBULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2005, v.26, 1819-1822
[지적재산권] 졸-겔 전이 키토산-폴리머 복합체 및 그의 용도국내 : 특허, 등록, 10-1335624, 2013
[지적재산권] 졸-겔 전이 키토산-폴리머 복합체 및 그의 용도국외 : 특허, 출원
[지적재산권] 온도 민감성 졸-젤 전이 PP-PLX-PP블록 공중합체 및 이의 제조 방법국내 : 특허, 등록, 10-0924430, 2009
[지적재산권] 온도 민감성 졸-젤 전이 폴리(에틸렌글리콜)/폴리(카보네이트) 블록 공중합체 및 이의 제조방법 (THERMOGELLING POLY(ETHYLENE GLYCOL)/POLYCARBONATE BLOCKCOPOLYMER AND PREPARATION METHOD THEREOF)국내 : 특허, 등록, 10-0795214, 2008
[지적재산권] Thermogelling oligopeptide polymer국외 : 특허, 등록