김완규 교수는 학부 생명과학 전공/바이오정보학 대학원 협동과정 소속 교수로 영국 캠브리지 대학교에서 박사 학위를 수여하였다. 전공 분야는 전산 시스템생물학 및 생명정보학이고, 최근에는 주로 AI 및 빅데이터 기반 신약개발 관련 연구를 수행하고 있으며, 랩 동료와 함께 Spin-off 벤처기업인 주식회사 카이팜을 설립하였다. 지난 15년 간 시스템약물학, 화학유전체학, 빅데이터 마이닝, 암 유전체 및 생체 네트워크 등 다양한 생명정보학 관련 연구를 수행하였고, Genome Biology, Nucleic Acids Research, Molecular Cancer, Nat. Comm, Nature Biotech. 등 ~40편의 SCI(E) 논문 및 다수의 국내외 특허를 출원/등록한 바 있다.
Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trialClinical and Molecular Hepatology, 2022, v.28 no.3, 497-509
Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trialClinical and Molecular Hepatology, 2022, v.28 no.3, 497-509
Enhanced Sensitivity of Nonsmall Cell Lung Cancer with Acquired Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors to Phenformin: The Roles of a Metabolic Shift to Oxidative Phosphorylation and Redox BalanceOxidative Medicine and Cellular Longevity, 2021, v.2021, 5428364
Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancerOncogene, 2020, v.39 no.23, 4567-4580
Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formationProceedings of the National Academy of Sciences of the United States of America, 2020, v.117 no.33, 19982-19993
Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axisEXPERIMENTAL AND MOLECULAR MEDICINE, 2020 , 1831-1844
Comparison of Target Features for Predicting Drug-Target Interactions by Deep Neural Network Based on Large-Scale Drug-Induced Transcriptome DataPHARMACEUTICS, 2019, v.11 no.8, 377
Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem CellsFRONTIERS IN CHEMISTRY, 2019, v.7, 298
miRseqViewer: multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing dataBIOINFORMATICS, 2015, v.31 no.4, 596-598
[학술지논문] 5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPARγ axis
NATURE COMMUNICATIONS, 2024, v.15
no.1
, 1024-1024
SCIE
[학술지논문] SARS-CoV-2 infection in severe asthma is associated with worsening of COVID-19 through respiratory NLRP3 inflammasome activation
ALLERGY, 2023, v.10
no.1111
, 15452-15452
[학술지논문] Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trial
Clinical and molecular hepatology, 2022, v.28
no.3
, 497-509
SCIE
[학술지논문] Crosstalk between YAP and TGF beta regulates SERPINE1 expression in mesenchymal lung cancer cells
INTERNATIONAL JOURNAL OF ONCOLOGY, 2021, v.58
no.1
, 111-121
SCI
[학술지논문] Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, v.117
no.33
, 19982-19993
SCI
[학술지논문] MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer
SCIENTIFIC REPORTS, 2020, v.10
no.1
, 2833-2833
SCI
[학술지논문] Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis
EXPERIMENTAL AND MOLECULAR MEDICINE, 2020, v.52
no.11
, 1831-1844
[학술지논문] CDRgator: An Integrative Navigator of Cancer Drug Resistance Gene Signatures
MOLECULES AND CELLS, 2019, v.42
no.3
, 237-244
SCI
[학술지논문] CSgator: an integrated web platform for compound set analysis
JOURNAL OF CHEMINFORMATICS, 2019, v.11
no.0
, 17-17
SCIE
[학술지논문] Comparison of Target Features for Predicting Drug-Target Interactions by Deep Neural Network Based on Large-Scale Drug-Induced Transcriptome Data
PHARMACEUTICS, 2019, v.11
no.8
, 377-377
SCIE
[학술지논문] In silico drug repositioning: from large-scale transcriptome data to therapeutics
ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42
no.10
, 879-889
SCIE
[학술지논문] Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells
FRONTIERS IN CHEMISTRY, 2019, v.7
no.0
, 298-298
SCIE
[학술발표] Assay Repositioning - Mining Drug Screening Big Data for Virtual Screening & Target DiscoveryKSBMB International Conference 2019, 대한민국, 제주, 2019-06-04
KSBMB International Conference 2019, 2019