연구실적

• The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation JOURNAL OF MOLECULAR CELL BIOLOGY, 2022, v.14 no.6, mjac037
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• Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation EXPERIMENTAL AND MOLECULAR MEDICINE, 2021, v.53 no.3, 346-357
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• Nm23-H1 activator phenylbutenoid dimer exerts cytotoxic effects on metastatic breast cancer cells by inducing mitochondrial dysfunction only under glucose starvation SCIENTIFIC REPORTS, 2021, v.11 no.1, 23549
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• Stepwise oxidations play key roles in the structural and functional regulations of DJ-1 BIOCHEMICAL JOURNAL, 2021, v.478 no.19, 3505-3525
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• Cataract-Associated New Mutants S175G/H181Q of beta Beta 2-Crystallin and P24S/S31G of gamma D-Crystallin Are Involved in Protein Aggregation by Structural Changes INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, v.21 no.18, 6504
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• Activity-Regulated Cytoskeleton-Associated Protein (Arc/Arg3.1) is Transiently Expressed after Heat Shock Stress and Suppresses Heat Shock Factor 1 Scientific Reports, 2019, v.9 no.1, 2592
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• Network-based integrated analysis of omics data reveal novel players ofTGF-beta 1-induced EMT in human peritoneal mesothelial cells SCIENTIFIC REPORTS, 2019, v.9, 1497
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• deMix: Decoding Deuterated Distributions from Heterogeneous Protein States via HDX-MS Scientific Reports, 2019, v.9 no.1, 3176
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• Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications MOLECULAR & CELLULAR PROTEOMICS, 2018, v.17 no.9, 1803-1823
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• Small molecule activator of Nm23/NDPK as an inhibitor of metastasis SCIENTIFIC REPORTS, 2018, v.8
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• Ubiquitin C-terminal hydrolase-L1 plays a key role in angiogenesis by regulating hydrogen peroxide generated by NADPH oxidase 4 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, v.495 no.1, 1567-1572
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• Calcium Ion Induced Structural Changes Promote Dimerization of Secretagogin, Which is Required for Its Insulin Secretory Function Scientific Reports, 2017, v.7 no.1
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• Heterogeneous nuclear ribonucleoprotein K inhibits heat shock-induced transcriptional activity of heat shock factor 1 JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, v.292 no.31, 12801-12812
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• ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation NATURE COMMUNICATIONS, 2016, v.7
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• Degradation of Redox-Sensitive Proteins including Peroxiredoxins and DJ-1 is Promoted by Oxidation-induced Conformational Changes and Ubiquitination SCIENTIFIC REPORTS, 2016, v.6
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• Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus MOLECULAR AND CELLULAR BIOLOGY, 2016, v.36 no.7, 1136-1151
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• Mechanistic elucidation guided by covalent inhibitors for the development of anti-diabetic PPARγ ligands Chemical Science, 2016, v.7 no.8, 5523-5529
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• Secretagogin affects insulin secretion in pancreatic beta-cells by regulating actin dynamics and focal adhesion BIOCHEMICAL JOURNAL, 2016, v.473, 1791-1803
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• Evidence for the Dimerization-Mediated Catalysis of Methionine Sulfoxide Reductase A from Clostridium oremlandii PLOS ONE, 2015, v.10 no.6
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• Hydrogen-deuterium exchange mass spectrometry for determining protein structural changes in drug discovery Archives of Pharmacal Research, 2015, v.38 no.10, 1737-1745
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• Mechanism of 1-Cys type methionine sulfoxide reductase Aregeneration by glutaredoxin Biochemical and Biophysical Research Communications, 2015
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• Proteomic Analysis of INS-1 Rat Insulinoma Cells: ER Stress Effects and the Protective Role of Exenatide, a GLP-1 Receptor Agonist PLOS ONE, 2015, v.10 no.3
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• ROSICS: CHEMISTRY AND PROTEOMICS OF CYSTEINE MODIFICATIONS IN REDOX BIOLOGY MASS SPECTROMETRY REVIEWS, 2015, v.34 no.2, 184-208
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• Translationally Controlled Tumor Protein induces epithelial to mesenchymal transition and promotes cell migration, invasion and metastasis SCIENTIFIC REPORTS, 2015, v.5
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• Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4 Oncotarget, 2015, v.6 no.18, 16287-16303
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• N-terminal truncated UCH-L1 prevents Parkinson's disease associated damage PLoS ONE, 2014, v.9 no.6
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• Sulfhydryl-Specific Probe for Monitoring Protein Redox Sensitivity ACS CHEMICAL BIOLOGY, 2014, v.9 no.12, 2883-2894
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• [학술발표] Modifications Control Protein Stability and Biological Functions in Redox Sensitive Proteins International Conference of the Korean Society for Molecular and Cellular Biology, 대한민국, 2126-09-01 International Conference of the Korean Society for Molecular and Cellular Biology, 2126

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