박진병 교수는 식품공학전공/환경식품공학부 소속 교수로 생물전환 및 미생물 대사공학 분야 연구의 권위자다. 스위스연방공대(ETH, Zurich) 생물공학과에서 박사학위를 받았으며, 지방산 생물전환 및 박테리아 기반 재조합 생촉매 개발 등에 대한 연구를 진행하고 있다. 2013년부터 산자부 산업핵심기술개발사업(과제명: Long-chain diacids(DC9~DC13)의 생물전환 공정과 그 응용제품(코팅제, 윤활제 등)의 개발)의 총괄책임자를 맡고 있으며, 현재까지 총 40여편의 논문을 <Angewandte Chemie International Edition>, <Advanced Synthesis and Catalysis>, <Biotechnology and Bioengineering> 등의 SCI급 국제학술지에 발표했다.
Biological Reaction Engineering for the Preparation of C9 Chemicals from Oleic Acid: 9-Aminononanoic Acid, 1,9-Nonanediol, 9-Amino-1-nonanol, and 1,9-DiaminononaneACS Catalysis, 2024, v.14 no.6, 4130-4138
Biotransformation of C20- and C22-polyunsaturated fatty acids and fish oil hydrolyzates to R,R-dihydroxy fatty acids as lipid mediators using double-oxygenating 15R-lipoxygenaseGreen Chemistry, 2024, v.26 no.8, 4665-4676
Lysolecithin-fatty acid liposomes as novel antibacterial agents to suppress the growth of periodontal Porphyromonas gingivalisFood Bioscience, 2024, v.59, 104059
Structure modeling-based characterization of ChnD, the 6-hydroxyhexanoate dehydrogenase from Acinetobacter sp. strain NCIMB 9871Journal of Biotechnology, 2024, v.392, 90-95
Efficient biotransformation of docosahexaenoic acid-rich oils into the lipid mediator resolvin D5 by cells expressing 15S-lipoxygenase using a bioreactorBioresource Technology, 2023, v.388, 129750
Engineering of two thiamine diphosphate-dependent enzymes for the regioselective condensation of C1-formaldehyde into C4-erythruloseInternational Journal of Biological Macromolecules, 2023, v.253, 127674
Multilayer Engineering of an Escherichia coli-Based Biotransformation System to Exclusively Produce Glycolic Acid from FormaldehydeACS Sustainable Chemistry and Engineering, 2023, v.11 no.3, 1078-1086
Structural and functional characterization of a thermostable secretory phospholipase A2 from Sciscionella marina and its application in liposome biotransformationActa crystallographica. Section D, Structural biology, 2023, v.79, 188-197
Variability of oral/taste sensitivity to fat: An investigation of attribution from detection threshold methods with repeated measurementsFood Research International, 2023, v.165, 112432
Engineering of a bacterial outer membrane vesicle to a nano-scale reactor for the biodegradation of β-lactam antibioticsJournal of Biotechnology, 2022, v.356, 1-7
Substrate-binding Site Engineering of Candida antarctica Lipase B to Improve Selectivity for Synthesis of 1-monoacyl-sn-glycerolsBiotechnology and Bioprocess Engineering, 2022, v.27 no.2, 234-243
Triplet–triplet annihilation-based photon-upconversion to broaden the wavelength spectrum for photobiocatalysisScientific Reports, 2022, v.12 no.1, 9397
Valorization of Soy Lecithin by Enzyme Cascade Reactions Including a Phospholipase A2, a Fatty Acid Double-Bond Hydratase, and/or a Photoactivated DecarboxylaseJournal of Agricultural and Food Chemistry, 2022, v.70 no.35, 10818-10825
Chemoenzymatic Cascade Conversion of Linoleic Acid into a Secondary Fatty Alcohol Using a Combination of 13S-Lipoxygenase, Chemical Reduction, and a Photo-Activated DecarboxylaseACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, v.9 no.32, 10837-10845
Enhancing acid tolerance of Escherichia coli via viroporin-mediated export of protons and its application for efficient whole-cell biotransformationMetabolic Engineering, 2021, v.67, 277-284
Construction of an engineered biocatalyst system for the production of medium-chain α,ω-dicarboxylic acids from medium-chain ω-hydroxycarboxylic acidsBiotechnology and Bioengineering, 2020, v.117 no.9, 2648-2657
Discovery and Engineering of a Microbial Double-Oxygenating Lipoxygenase for Synthesis of Dihydroxy Fatty Acids as Specialized Proresolving MediatorsACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2020, v.8 no.43, 16172-16183
Engineering of a Microbial Cell Factory for the Extracellular Production of Catalytically Active Phospholipase A(2) of Streptomyces violaceoruberJOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2020, v.30 no.8, 1244-1251
Increased Production of omega-Hydroxynonanoic Acid and alpha,omega-Nonanedioic Acid from Olive Oil by a Constructed Biocatalytic SystemJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, v.68 no.35, 9488-9495
Understanding the molecular properties of the E1 subunit (SucA) of alpha-ketoglutarate dehydrogenase complex from Vibrio vulnificus for the enantioselective ligation of acetaldehydes into (R)-acetoinCATALYSIS SCIENCE & TECHNOLOGY, 2020, v.10 no.1, 79-85
Characterization and application of chemical-resistant polyurethane-based enzyme and whole cell compartmentsJournal of Biotechnology, 2019, v.289, 31-38
Cofactor specificity engineering of a long-chain secondary alcohol dehydrogenase from Micrococcus luteus for redox-neutral biotransformation of fatty acidsCHEMICAL COMMUNICATIONS, 2019, v.55 no.96, 14462-14465
Enzymatic synthesis of new hepoxilins and trioxilins from polyunsaturated fatty acids Electronic supplementary information (ESI) available. See DOI: 10.1039/c9gc01031aGREEN CHEMISTRY, 2019, v.21 no.11, 3172-3181
Enzyme Cascade Reactions for the Biosynthesis of Long Chain Aliphatic Amines from Renewable Fatty AcidsADVANCED SYNTHESIS & CATALYSIS, 2019, v.361 no.6, 1359-1367
Esterification of Secondary Alcohols and Multi-hydroxyl Compounds by Candida antarctica Lipase B and SubtilisinBIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2019, v.24 no.1, 41-47
Multi-Step Enzymatic Synthesis of 1,9-Nonanedioic Acid from a Renewable Fatty Acid and Its Application for the Enzymatic Production of BiopolyestersPOLYMERS, 2019, v.11 no.10, 1690
Multi-level engineering of Baeyer-Villiger monooxygenase-based Escherichia coli biocatalysts for the production of C9 chemicals from oleic acidMETABOLIC ENGINEERING, 2019, v.54, 137-144
Structural basis for the selective addition of an oxygen atom to cyclic ketones by Baeyer-Villiger monooxygenase from Parvibaculum lavamentivoransBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, v.512 no.3, 564-570
-hydroxyundec-9-enoic acid induces apoptosis by ROS mediated JNK and P38 phosphorylation in breast cancer cell linesJOURNAL OF CELLULAR BIOCHEMISTRY, 2018, v.119 no.1, 998-1007
Improving catalytic activity of the Baeyer-Villiger monooxygenase-based Escherichia coli biocatalysts for the overproduction of (Z)-11-(heptanoyloxy) undec-9-enoic acid from ricinoleic acidSCIENTIFIC REPORTS, 2018, v.8
Intracellular transformation rates of fatty acids are influenced by expression of the fatty acid transporter FadL in Escherichia coli cell membraneJOURNAL OF BIOTECHNOLOGY, 2018, v.281, 161-167
Regiospecific Conversion of Lipids and Fatty Acids through Enzymatic Cascade ReactionsLipid Modification by Enzymes and Engineered Microbes, 2018 , 139-155
Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificusJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, v.66 no.40, 10608-10616
Bioprocess engineering to produce 9-(nonanoyloxy) nonanoic acid by a recombinant Corynebacterium glutamicum-based biocatalystJournal of Industrial Microbiology and Biotechnology, 2017, v.44 n.9, 1-11
Co-expression of two heterologous lactate dehydrogenases genes in Kluyveromyces marxianus for L-lactic acid productionJournal of Biotechnology, 2017, v.241, 81-86
Comparison of biochemical properties of the original and newly identified oleate hydratases from Stenotrophomonas maltophiliaApplied and Environmental Microbiology, 2017, v.83 no.9
Engineering Escherichia coli BL21 genome to improve the heptanoic acid tolerance by using CRISPR-Cas9 systemBIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2017, v.22 no.3, 231-238
Gene cloning of an efficiency oleate hydratase from Stenotrophomonas nitritireducens for polyunsaturated fatty acids and its application in the conversion of plant oils to 10-hydroxy fatty acidsBiotechnology and Bioengineering, 2017, v.114 no.1, 74-82
Activation of the Glutamic Acid-Dependent Acid Resistance System in Escherichia coli BL21(DE3) Leads to Increase of the Fatty Acid Biotransformation ActivityPLOS ONE, 2016, v.11 no.9
Combined Biocatalytic and Chemical Transformations of Oleic Acid to ω-Hydroxynonanoic Acid and α,ω-Nonanedioic AcidAdvanced Synthesis and Catalysis, 2016, v.358 no.19, 3084-3092
Engineering of Baeyer-Villiger monooxygenase-based Escherichia coli biocatalyst for large scale biotransformation of ricinoleic acid into (Z)-11-(heptanoyloxy)undec-9-enoic acidScientific Reports, 2016, v.6
Adding value to plant oils and fatty acids: Biological transformation of fatty acids into omega-hydroxycarboxylic, alpha,omega-dicarboxylic, and omega-aminocarboxylic acidsJOURNAL OF BIOTECHNOLOGY, 2015, v.216, 158-166
Biotransformation of Linoleic Acid into Hydroxy Fatty Acids and Carboxylic Acids Using a Linoleate Double Bond Hydratase as Key EnzymeADVANCED SYNTHESIS & CATALYSIS, 2015, v.357 no.42038, 408-416
Display of membrane proteins on the heterologous caveolae carved by caveolin-1 in the Escherichia coli cytoplasmEnzyme and Microbial Technology, 2015, v.79-80, 55-62
Enzyme fusion for whole-cell biotransformation of long-chain sec-alcohols into estersAPPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015, v.99 no.15, 6267-6275
Fatty acid hydration activity of a recombinant Escherichia coli-based biocatalyst is improved through targeting the oleate hydratase into the periplasmBiotechnology Journal, 2015, v.10 no.12
Microbial Synthesis of Plant Oxylipins from gamma-Linolenic Acid through Designed Biotransformation PathwaysJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015, v.63 no.10, 2773-2781
Production of 13S-hydroxy-9(Z)-octadecenoic acid from linoleic acid by whole recombinant cells expressing linoleate 13-hydratase from Lactobacillus acidophilusJournal of Biotechnology, 2015, v.208, 1-10
Whole Cell Bioconversion of Ricinoleic Acid to 12-Ketooleic Acid by Recombinant Corynebacterium glutamicum-Based BiocatalystJOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2015, v.25 no.4, 452-458
Engineering the substrate-binding domain of an esterase enhances its hydrolytic activity toward fatty acid estersPROCESS BIOCHEMISTRY, 2014, v.49 no.12, 2101-2106
Genome-scale metabolic network reconstruction and in silico flux analysis of the thermophilic bacterium Thermus thermophilus HB27MICROBIAL CELL FACTORIES, 2014, v.13, Article ID 61
High temperature stimulates acetic acid accumulation and enhances the growth inhibition and ethanol production by Saccharomyces cerevisiae under fermenting conditionsAPPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2014, v.98 no.13, 6085-6094
Production of omega-hydroxyundec-9-enoic acid and n-heptanoic acid from ricinoleic acid by recombinant Escherichia coli-based biocatalystPROCESS BIOCHEMISTRY, 2014, v.49 no.4, 617-622
Recent progress in development of synthetic biology platforms and metabolic engineering of Corynebacterium glutamicumJOURNAL OF BIOTECHNOLOGY, 2014, v.180, 43-51
Stereospecific production of 9R-hydroxy-10E,12Z-octadecadienoic acid from linoleic acid by recombinant Escherichia coli cells expressing 9R-lipoxygenase from Nostoc sp SAG 25.82JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2014, v.104, 56-63
ω-Hydroxyundec-9-enoic acid induces apoptosis through ROS-mediated endoplasmic reticulum stress in non-small cell lung cancer cellsBiochemical and Biophysical Research Communications, 2014, v.448 no.3
[학술지논문] Multilayer Engineering of an Escherichia coli-Based Biotransformation System to Exclusively Produce Glycolic Acid from Formaldehyde
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2023, v.11
no.3
, 1078-1086
SCIE
[학술지논문] Variability of oral/taste sensitivity to fat: An investigation of attribution from detection threshold methods with repeated measurements
FOOD RESEARCH INTERNATIONAL, 2023, v.165
no.112432
, 1-11
SCIE
[학술지논문] Bacterial Outer Membrane Vesicles as Nano-Scale Bioreactors: A Fatty Acid Conversion Case Study
CHEMCATCHEM, 2021, v.13
no.19
, 4080-4086
SCIE
[학술지논문] Chemoenzymatic Cascade Conversion of Linoleic Acid into a Secondary Fatty Alcohol Using a Combination of 13S-Lipoxygenase, Chemical Reduction, and a Photo-Activated Decarboxylase
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, v.9
no.32
, 10837-10845
SCIE
[학술지논문] Enhancing acid tolerance of Escherichia coli via viroporin-mediated export of protons and its application for efficient whole-cell biotransformation
METABOLIC ENGINEERING, 2021, v.67
no.-
, 277-284
SCIE
[학술지논문] Design and engineering of whole-cell biocatalytic cascades for the valorization of fatty acids
CATALYSIS SCIENCE & TECHNOLOGY, 2020, v.10
no.1
, 46-64
SCIE
[학술지논문] Discovery and Engineering of a Microbial Double-Oxygenating Lipoxygenase for Synthesis of Dihydroxy Fatty Acids as Specialized Proresolving Mediators
ACS SUSTAINABLE CHEMISTRY ENGINEERING, 2020, v.8
no.43
, 16172-16183
SCIE
[학술지논문] Increased Production of omega-Hydroxynonanoic Acid and alpha,omega-Nonanedioic Acid from Olive Oil by a Constructed Biocatalytic System
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, v.68
no.35
, 9488-9495
SCI
[학술지논문] Photobiocatalytic synthesis of chiral secondary fatty alcohols from renewable unsaturated fatty acids
NATURE COMMUNICATIONS, 2020, v.11
no.1
, 1-8
SCI
[학술지논문] Understanding the molecular properties of the E1 subunit (SucA) of alpha-ketoglutarate dehydrogenase complex from Vibrio vulnificus for the enantioselective ligation of acetaldehydes into (R)-acetoin
CATALYSIS SCIENCE & TECHNOLOGY, 2020, v.10
no.1
, 79-85
SCIE
[학술지논문] Whole-Cell Photoenzymatic Cascades to Synthesize Long-Chain Aliphatic Amines and Esters from Renewable Fatty Acids
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, v.59
no.18
, 7024-7028
SCI
[학술지논문] Characterization and application of chemical-resistant polyurethane-based enzyme and whole cell compartments
JOURNAL OF BIOTECHNOLOGY, 2019, v.289
no.-
, 31-38
SCI
[학술지논문] Cofactor specificity engineering of a long-chain secondary alcohol dehydrogenase from Micrococcus luteus for redox-neutral biotransformation of fatty acids
CHEMICAL COMMUNICATIONS, 2019, v.55
no.96
, 14462-14465
SCI
[학술지논문] Endocytosing Escherichia coil as a Whole-Cell Biocatalyst of Fatty Acids
ACS SYNTHETIC BIOLOGY, 2019, v.8
no.5
, 1055-1066
SCIE
[학술지논문] Enzymatic synthesis of new hepoxilins and trioxilins from polyunsaturated fatty acids Electronic supplementary information (ESI) available. See DOI: 10.1039/c9gc01031a
GREEN CHEMISTRY, 2019, v.21
no.11
, 3172-3181
SCI
[학술지논문] Enzyme Cascade Reactions for the Biosynthesis of Long Chain Aliphatic Amines from Renewable Fatty Acids
ADVANCED SYNTHESIS & CATALYSIS, 2019, v.361
no.6
, 1359-1367
SCI
[학술지논문] Esterification of Secondary Alcohols and Multi-hydroxyl Compounds by Candida antarctica Lipase B and Subtilisin
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2019, v.24
no.1
, 41-47
SCIE
[학술지논문] Multi-Step Enzymatic Synthesis of 1,9-Nonanedioic Acid from a Renewable Fatty Acid and Its Application for the Enzymatic Production of Biopolyesters
POLYMERS, 2019, v.11
no.10
, 1690-1690
SCIE
[학술지논문] Multi-level engineering of Baeyer-Villiger monooxygenase-based Escherichia coli biocatalysts for the production of C9 chemicals from oleic acid
METABOLIC ENGINEERING, 2019, v.54
no.0
, 137-144
SCIE
[학술지논문] Structural basis for the selective addition of an oxygen atom to cyclic ketones by Baeyer-Villiger monooxygenase from Parvibaculum lavamentivorans
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, v.512
no.3
, 564-570
SCI
[학술발표] Multi-step enzymatic synthesis of C9 to C12 w-aminocarboxylic acids from renewable long chain fatty acidsBIOTRANS 2019, 네델란드, 2019-07-07
BIOTRANS 2019, 2019
[학술발표] Production of secretory phospholipase A2 from Streptomyces violaceoruber by using Pichia pastorisBIOTRANS 2019, 네델란드, 2019-07-07
BIOTRANS 2019, 2019
[지적재산권] 슈도모나스 유래 리폭시게나아제 기반 재조합 대장균 및 이를 이용한 히드록시 지방산 및 이차 지방알콜 제조방법국내 : 특허, 등록, 10-2579073, 2023