연구실적

• Synthesis and biological assessment of chalcone and pyrazoline derivatives as novel inhibitor for ELF3-MED23 interaction eLife, 2024, v.13
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• Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents Bioorganic Chemistry, 2023, v.130, 106260
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• Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure–activity relationships Bioorganic and Medicinal Chemistry, 2023, v.91, 117403
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• Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers Journal of Advanced Research, 2023, v.47, 173-187
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• Hypoxia-induced ELF3 promotes tumor angiogenesis through IGF1/IGF1R EMBO Reports, 2022, v.23 no.8, e52977
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• Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships Bioorganic and Medicinal Chemistry Letters, 2022, v.60, 128606
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• 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase II alpha inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships BIOORGANIC CHEMISTRY, 2021, v.116, 105349
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• Ak-i-190, a new catalytic inhibitor of topoisomerase ii with anti-proliferative and pro-apoptotic activity on androgen-negative prostate cancer cells International Journal of Molecular Sciences, 2021, v.22 no.20, 11246
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• Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison European Journal of Medicinal Chemistry, 2021, v.226, 113860
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• Drug-like small molecule HSP27 functional inhibitor sensitizes lung cancer cells to gefitinib or cisplatin by inducing altered cross-linked Hsp27 dimers Pharmaceutics, 2021, v.13 no.5, 630
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• Identification of Indicators for Preterm Birth Using Retinoid Metabolites METABOLITES, 2021, v.11 no.7, 443
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