이윤실(李潤實) 교수

약학과[대학원] /약학부 /제약산업학과[대학원]

이윤실 프로필 사진
이윤실 교수는 약학대학 약학과 소속 교수로 방사선연구분야 전문가이다. 이화여대 약학과에서 박사학위를 받았고 미국 암연구소에서 박사후연구원을 거쳐 2010년까지 18여년간 한국원자력의학원에서 방사선관련 연구를 수행하였다. 2010년에 이화여대로 부임하여 강의와 연구활동을 지속하고 있으며 여성원자력전문인협회 부회장, 방사선생명과학회 회장, 약학회 학술위원장등을 맡아 활동하고 있으며 현재까지 SCI 논문 200여편 게재 및 특허 20여건을 등록했다.   
  • 대학원장/섬유화질환제어연구센터소장
  • 약학관 B동 214호
  • 02-3277-3022
연구실적
  • Low-Dose Radiation Therapy for Neurological Disorders: A Double-Edged Sword DISCOVERY MEDICINE, 2024, v.36 no.184, 898-912
    SCIE Scopus dColl.
  • Radiosensitizing effect of a novel CTSS inhibitor by enhancing BRCA1 protein stability in triple-negative breast cancer cells Cancer Science, 2024, v.115 no.6, 2036-2048
    SCIE Scopus dColl.
  • Standigm ASK™: knowledge graph and artificial intelligence platform applied to target discovery in idiopathic pulmonary fibrosis Briefings in Bioinformatics, 2024, v.25 no.2, bbae035
    SCIE Scopus dColl.
  • Transcriptional Changes in Radiation-Induced Lung Injury: A Comparative Analysis of Two Radiation Doses for Preclinical Research International Journal of Molecular Sciences, 2024, v.25 no.7, 3766
    SCIE Scopus dColl.
  • BRCA1 deficiency in triple-negative breast cancer: Protein stability as a basis for therapy Biomedicine and Pharmacotherapy, 2023, v.158, 114090
    SCIE Scopus dColl.
  • Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents Bioorganic Chemistry, 2023, v.130, 106260
    SCIE Scopus dColl.
  • Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis FRONTIERS IN PHARMACOLOGY, 2023, v.14, 1203033
    SCIE Scopus dColl.
  • Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial-Mesenchymal Transition in the Lungs Advanced Functional Materials, 2023, v.33 no.7, 2209432
    SCIE Scopus dColl.
  • Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis Journal of Medicinal Chemistry, 2023, v.66 no.23, 16342-16363
    SCIE Scopus dColl.
  • NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1β Signaling Pathway International Journal of Molecular Sciences, 2023, v.24 no.22, 16265
    SCIE Scopus dColl.
  • The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis Journal of Biomedical Science, 2023, v.30 no.1, 2
    SCIE Scopus dColl.
  • Activation of the HSP27-AKT axis contributes to gefitinib resistance in non-small cell lung cancer cells independent of EGFR mutations Cellular Oncology, 2022, v.45 no.5, 913-930
    SCIE Scopus dColl.
  • Effects of intermediate frequency electromagnetic fields: a review of animal studies International Journal of Radiation Biology, 2022
    SCIE Scopus dColl.
  • Efferocytosis and enhanced FPR2 expression following apoptotic cell instillation attenuate radiation-induced lung inflammation and fibrosis Biochemical and Biophysical Research Communications, 2022, v.601, 38-44
    SCIE Scopus dColl.
  • Hypoxia-induced ELF3 promotes tumor angiogenesis through IGF1/IGF1R EMBO Reports, 2022, v.23 no.8, e52977
    SCIE Scopus dColl.
  • Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1 Nature Communications, 2022, v.13 no.1, 6732
    SCIE Scopus dColl.
  • Therapeutic potential of targeting cathepsin S in pulmonary fibrosis Biomedicine and Pharmacotherapy, 2022, v.145, 112245
    SCIE Scopus dColl.
  • Drug-like small molecule HSP27 functional inhibitor sensitizes lung cancer cells to gefitinib or cisplatin by inducing altered cross-linked Hsp27 dimers Pharmaceutics, 2021, v.13 no.5, 630
    SCIE Scopus dColl.
  • HSPB1 inhibitor J2 attenuates lung inflammation through direct modulation of Ym1 production and paracrine signaling BIOMEDICINE & PHARMACOTHERAPY, 2021, v.143, 112225
    SCIE Scopus dColl.
  • The protective effects of emf‐lte against dna double‐strand break damage in vitro and in vivo International Journal of Molecular Sciences, 2021, v.22 no.10, 5134
    SCIE Scopus dColl.
  • Behavioral changes and gene profile alterations after chronic 1,950-MHz radiofrequency exposure: An observation in C57BL/6 mice Brain and Behavior, 2020, v.10 no.11, e01815
    SCIE Scopus dColl.
  • Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1 CELL DEATH & DISEASE, 2020, v.11 no.5
    SCIE Scopus dColl.
  • Effects of Radiofrequency Electromagnetic Fields and Ionizing Radiation on Amyloid Precursor Protein Processing and Cell Death Journal of Electromagnetic Engineering and Science, 2020, v.20 no.4, 307-319
    SCIE Scopus dColl.
  • LXA(4)-FPR2 signaling regulates radiation-induced pulmonary fibrosis via crosstalk with TGF-beta/Smad signaling CELL DEATH & DISEASE, 2020, v.11 no.8, 653
    SCIE Scopus dColl.
  • Lung-targeted delivery of TGF-beta antisense oligonucleotides to treat pulmonary fibrosis JOURNAL OF CONTROLLED RELEASE, 2020, v.322, 108-121
    SCIE Scopus dColl.
  • Radiation-Induced Lung Fibrosis: Preclinical Animal Models and Therapeutic Strategies CANCERS, 2020, v.12 no.6, 1561
    SCIE Scopus dColl.
  • Specific Roles of HSP27 S15 Phosphorylation Augmenting the Nuclear Function of HER2 to Promote Trastuzumab Resistance CANCERS, 2020, v.12 no.6, 1540
    SCIE Scopus dColl.
  • Comprehensive analysis of transcriptomic changes induced by low and high doses of bisphenol A in HepG2 spheroids in vitro and rat liver in vivo ENVIRONMENTAL RESEARCH, 2019, v.173, 124-134
    SCIE Scopus dColl.
  • Di-2-ethylhexylphthalate promotes thyroid cell proliferation and DNA damage through activating thyrotropin-receptor-mediated pathways in vitro and in vivo Food and Chemical Toxicology, 2019, v.124, 265-272
    SCIE Scopus dColl.
  • Identification of molecular signatures involved in radiation-induced lung fibrosis Journal of Molecular Medicine, 2019, v.97 no.1, 37-47
    SCIE Scopus dColl.
  • Radiosensitivity of Cancer Cells Is Regulated by Translationally Controlled Tumor Protein CANCERS, 2019, v.11 no.3, 386
    SCIE Scopus dColl.
  • Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation CELL DEATH AND DIFFERENTIATION, 2019, v.26 no.5, 812-825
    SCIE Scopus dColl.
  • Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment? CANCERS, 2019, v.11 no.8, 1195
    SCIE Scopus dColl.
  • The Hsp27-Mediated IkB alpha-NF kappa B Signaling Axis Promotes Radiation-Induced Lung Fibrosis CLINICAL CANCER RESEARCH, 2019, v.25 no.17, 5364-5375
    SCIE Scopus dColl.
  • HSP27 inhibitor attenuates radiation-induced pulmonary inflammation Scientific Reports, 2018, v.8 no.1
    SCIE Scopus dColl.
  • Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, v.19 no.7, 2103
    SCIE Scopus dColl.
  • Long-term RF exposure on behavior and cerebral glucose metabolism in 5xFAD mice Neuroscience Letters, 2018, v.666, 64-69
    SCIE Scopus dColl.
  • Metformin Alleviates Radiation-Induced Skin Fibrosis via the Downregulation of FOXO3 CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, v.48 no.3, 959-970
    SCIE Scopus dColl.
  • Pharmacology of natural radioprotectors ARCHIVES OF PHARMACAL RESEARCH, 2018, v.41 no.11, 1033-1050
    SCIE Scopus KCI dColl.
  • Submicromolar bisphenol A induces proliferation and DNA damage in human hepatocyte cell lines in vitro and in juvenile rats in vivo FOOD AND CHEMICAL TOXICOLOGY, 2018, v.111, 125-132
    SCIE Scopus dColl.
  • Assessment of ionizing radiation induced dicentric chromosome and micronuclei in human peripheral blood lymphocytes for preliminary reconstruction of cytogenetic biodosimetry Atom Indonesia, 2017, v.43 no.1, 47-54
    Scopus dColl.
  • Heat Shock Protein-Inducing Property of Diarylheptanoid Containing Chalcone Moiety from Alpinia katsumadai MOLECULES, 2017, v.22 no.10
    SCIE Scopus dColl.
  • Sensitization of lung cancer cells by altered dimerization of HSP27 Oncotarget, 2017, v.8 no.62, 105372-105382
    SCIE Scopus dColl.
  • Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27 European Journal of Medicinal Chemistry, 2017, v.139, 892-900
    SCIE Scopus dColl.
  • The Conjugated Double Bond of Coniferyl Aldehyde Is Essential for Heat Shock Factor 1 Mediated Cytotoprotection JOURNAL OF NATURAL PRODUCTS, 2017, v.80 no.8, 2379-2383
    SCIE Scopus dColl.
  • The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma ONCOTARGET, 2017, v.8 no.15, 24932-24948
    SCIE Scopus dColl.
  • The efficacy of human placenta-derived mesenchymal stem cells on radiation enteropathy along with proteomic biomarkers predicting a favorable response Stem Cell Research and Therapy, 2017, v.8 no.1
    SCIE Scopus dColl.
  • The pentapeptide Gly-Thr-Gly-Lys-Thr confers sensitivity to anti-cancer drugs by inhibition of CAGE binding to GSK3 beta and decreasing the expression of cyclinD1 ONCOTARGET, 2017, v.8 no.8, 13632-13651
    SCIE Scopus dColl.
  • miR-122-SOCS1-JAK2 axis regulates allergic inflammation and allergic inflammation-promoted cellular interactions ONCOTARGET, 2017, v.8 no.38, 63155-63176
    SCIE Scopus dColl.
  • 1950MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice BIOELECTROMAGNETICS, 2016, v.37 no.6, 391-399
    SCIE Scopus dColl.
  • Focal exposure of limited lung volumes to high-dose irradiation down-regulated organ development-related functions and up-regulated the immune response in mouse pulmonary tissues BMC GENETICS, 2016, v.17
    SCIE Scopus dColl.
  • Heparan sulfation is essential for the prevention of cellular senescence CELL DEATH AND DIFFERENTIATION, 2016, v.23 no.2, 417-429
    SCIE Scopus dColl.
  • Identification of radiation response genes and proteins from mouse pulmonary tissues after high-dose per fraction irradiation of limited lung volumes International Journal of Radiation Biology, 2016, 25 Oct 2016, 1-10
    SCIE Scopus dColl.
  • Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response PLOS ONE, 2016, v.11 no.5
    SCIE Scopus dColl.
  • MiR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2 Oncotarget, 2016, v.7 no.9, 10297-10321
    SCIE Scopus dColl.
  • Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules ONCOTARGET, 2016, v.7 no.33, 53178-53190
    SCIE Scopus dColl.
  • Pro-apoptotic Noxa is involved in ablative focal irradiation-induced lung injury Journal of Cellular and Molecular Medicine, 2016, 15 Nov 2016
    Scopus dColl.
  • 1950 MHz Electromagnetic Fields Ameliorate A beta Pathology in Alzheimer's Disease Mice CURRENT ALZHEIMER RESEARCH, 2015, v.12 no.5, 481-492
    SCIE Scopus dColl.
  • A hypoxia-induced vascular endothelial-to-mesenchymal transition in development of radiation-induced pulmonary fibrosis Clinical Cancer Research, 2015, v.21 no.16, 3716-3726
    SCIE Scopus dColl.
  • Chalcones from Angelica keiskei: Evaluation of Their Heat Shock Protein Inducing Activities Journal of Natural Products, 2015, v.78 no.10, 2481-2487
    SCIE Scopus dColl.
  • Coniferyl Aldehyde Reduces Radiation Damage Through Increased Protein Stability of Heat Shock Transcriptional Factor 1 by Phosphorylation INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2015, v.91 no.4, 807-816
    SCIE Scopus dColl.
  • Coniferyl aldehyde attenuates radiation enteropathy by inhibiting cell death and promoting endothelial cell function PLoS ONE, 2015, v.10 no.6
    SCIE Scopus dColl.
  • DIFFERENTIAL EXPRESSION OF RADIATION RESPONSE GENES IN SPLEEN, LUNG, AND LIVER OF RATS FOLLOWING ACUTE OR CHRONIC RADIATION EXPOSURE 방사선방어학회지, 2015, v.40 no.1, 25-35
    KCI dColl.
  • Effect of extremely low frequency magnetic fields on cell proliferation and gene expression Bioelectromagnetics, 2015, v.36 no.7, 506-516
    SCIE Scopus dColl.
  • Effect of whole-body exposure to the 848.5 MHz code division multiple access (CDMA) electromagnetic field on adult neurogenesis in the young, healthy rat brain INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2015, v.91 no.4, 354-359
    SCIE Scopus dColl.
  • Effects on G2/M Phase Cell Cycle Distribution and Aneuploidy Formation of Exposure to a 60 Hz Electromagnetic Field in Combination with Ionizing Radiation or Hydrogen Peroxide in L132 Nontumorigenic Human Lung Epithelial Cells KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2015, v.19 no.2, 119-124
    SCIE KCI Scopus dColl.
  • Eight hours of nocturnal 915 MHz radiofrequency identification (RFID) exposure reduces urinary levels of melatonin and its metabolite via pineal arylalkylamine N-acetyltransferase activity in male rats International Journal of Radiation Biology, 2015, v.91 no.11, 898-907
    SCIE Scopus dColl.
  • Heat shock factor 1, an inhibitor of non-homologous end joining repair Oncotarget, 2015, v.6 no.30, 29712-29724
    SCIE Scopus dColl.
  • Metabolomic study of urinary polyamines in rat exposed to 915 MHz radiofrequency identification signal Amino Acids, 2015, 29 AUG 2015
    SCIE Scopus dColl.
  • MicroRNA-26a/-26b-COX-2-MIP-2 loop regulates allergic inflammation and allergic inflammation-promoted enhanced tumorigenic and metastatic potential of cancer cells Journal of Biological Chemistry, 2015, v.290 no.22, 14245-14266
    SCIE Scopus dColl.
  • Pyruvate metabolism: A therapeutic opportunity in radiation-induced skin injury Biochemical and Biophysical Research Communications, 2015, v.460 no.3, 504-510
    SCIE Scopus dColl.
  • The inflammasome accelerates radiation-induced lung inflammation and fibrosis in mice ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2015, v.39 no.2, 917-926
    SCIE Scopus dColl.
  • 2,4-Bis(4-hydroxybenzyl)phenol Inhibits Heat Shock Transcription Factor 1 and Sensitizes Lung Cancer Cells to Conventional Anticancer Modalities JOURNAL OF NATURAL PRODUCTS, 2014, v.77 no.5, 1123-1129
    SCIE Scopus dColl.
  • Absence of DNA damage after 60-Hz electromagnetic field exposure combined with ionizing radiation, hydrogen peroxide, or c-Myc overexpression RADIATION AND ENVIRONMENTAL BIOPHYSICS, 2014, v.53 no.1, 93-101
    SCIE Scopus dColl.
  • Combined Effects of 60 Hz Electromagnetic Field Exposure With Various Stress Factors on Cellular Transformation in NIH3T3 Cells (vol 33, pg 207, 2012) BIOELECTROMAGNETICS, 2014, v.35 no.1, 76-77
    SCIE Scopus dColl.
  • Effect of 915 MHz RFID exposure on changes of body temperature in rats IEEE International Symposium on Electromagnetic Compatibility, 2014, v.2014-December, 170-173
    Scopus dColl.
  • Effects of combined radiofrequency radiation exposure on levels of reactive oxygen species in neuronal cells JOURNAL OF RADIATION RESEARCH, 2014, v.55 no.2, 265-276
    SCIE Scopus dColl.
  • Evaluation of premature senescence and senescence biomarkers in carcinoma cells and xenograft mice exposed to single or fractionated irradiation ONCOLOGY REPORTS, 2014, v.31 no.5, 2229-2235
    SCIE Scopus dColl.
  • Histone Deacetylase-3 Mediates Positive Feedback Relationship between Anaphylaxis and Tumor Metastasis JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, v.289 no.17, 12126-12144
    SCIE Scopus dColl.
  • Increased gamma-H2AX by exposure to a 60-Hz magnetic fields combined with ionizing radiation, but not hydrogen peroxide, in non-tumorigenic human cell lines INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2014, v.90 no.4, 291-298
    SCIE Scopus dColl.
  • MMP9 Processing of HSPB1 Regulates Tumor Progression PLOS ONE, 2014, v.9 no.1, e85509
    SCIE Scopus dColl.
  • Special issue in the honor of prof. Okpyo Zee Natural Product Sciences, 2014, v.20 no.2
    KCI Scopus dColl.
  • Transglutaminase II/MicroRNA-218/-181a Loop Regulates Positive Feedback Relationship between Allergic Inflammation and Tumor Metastasis JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, v.289 no.43, 29483-29505
    SCIE Scopus dColl.
  • miR-326-Histone Deacetylase-3 Feedback Loop Regulates the Invasion and Tumorigenic and Angiogenic Response to Anti-cancer Drugs JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, v.289 no.40, 28019-28039
    SCIE Scopus dColl.
  • [학술지논문] GTSE1 driven ZEB1 stabilization promotes pulmonary fibrosis through the epithelial-to-mesenchymal transition MOLECULAR THERAPY, 2024, v.32 no.11 , 1-20
    SCIE
  • [학술지논문] Low Dose Radiation Therapy for Neurological Disorders: A Double-Edged Sword DISCOVERY MEDICINE, 2024, v.36 no.184 , 898-912
    SCIE
  • [학술지논문] Phosphorylation of BRCA1 at serine 1387 plays a critical role in cathepsin S-mediated radiation resistance via BRCA1 degradation and BCL2 stabilization BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2024, v.1871 no.0 , 167523-167534
    SCIE
  • [학술지논문] Radiosensitizing effect of a novel CTSS inhibitor by enhancing BRCA1 protein stability in triple negative breast cancer cells Cancer Science, 2024, v.115 no.2 , 2036-2048
    SCIE
  • [학술지논문] Rutaecarpine, Isolated from Evodia rutaecarpa, Inhibits Epithelial-Mesenchymal Transition and Cellular Senescence in a Mouse Model of Pulmonary Fibrosis Natural Product Sciences, 2024, v.30 no.3 , 190-197
    Scopus
  • [학술지논문] Transcirptional Changes in Radiation-induced LUng Injry: A Comparative Analysis of Two Radiation Doses for Preclinical Research International Journal of Molecular Sciences, 2024, v.25 no.0 , 3766-3772
    SCIE
  • [학술지논문] BRCA1 deficiency in triple-negative breast cancer: Protein stability as a basis for therapy BIOMEDICINE & PHARMACOTHERAPY, 2023, v.158 no.0 , 114090-114090
    SCIE
  • [학술지논문] Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents BIOORGANIC CHEMISTRY, 2023, v.130 no.1062600 , 1-11
    SCIE
  • [학술지논문] Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis FRONTIERS IN PHARMACOLOGY, 2023, v.14 no.0 , 1203033-1203033
    SCIE
  • [학술지논문] Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis JOURNAL OF MEDICINAL CHEMISTRY, 2023, v.66 no.23 , 16342-16363
    SCIE
  • [학술지논문] NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1β Signaling Pathway INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, v.24 no.22 , 16265-16265
    SCIE
  • [학술지논문] The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis JOURNAL OF BIOMEDICAL SCIENCE, 2023, v.30 no.1 , 2-2
    SCIE
  • [학술지논문] Efferocytosis and enhanced FPR2 expression following apoptotic cell instillation attenuate radiation-induced lung inflammation and fibrosis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, v.601 no.0 , 38-44
    SCI
  • [학술지논문] Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1 NATURE COMMUNICATIONS, 2022, v.13 no.1 , 6732-6732
    SCI
  • [학술지논문] Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers PHARMACEUTICS, 2021, v.13 no.5 , 630-649
    SCIE
  • [학술지논문] The Protective Effects of EMF-LTE against DNA Double-Strand Break Damage In Vitro and In Vivo INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.10 , 5134-5134
    SCIE
  • [학술지논문] Behavioral changes and gene profile alterations after chronic 1,950-MHz radiofrequency exposure: An observation in C57BL/6 mice BRAIN AND BEHAVIOR, 2020, v.10 no.11 , 01815-01815
    SCIE
  • [학술지논문] Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1 CELL DEATH & DISEASE, 2020, v.11 no.5 , 395-409
    SCIE
  • [학술지논문] Effects of Radiofrequency Electromagnetic Fields and Ionizing Radiation on Amyloid Precursor Protein Processing and Cell Death Journal of Electromagnetic Engineering and Science, 2020, v.20 no.4 , 307-319
    Scopus
  • [학술지논문] LXA(4)-FPR2 signaling regulates radiation-induced pulmonary fibrosis via crosstalk with TGF-beta/Smad signaling CELL DEATH & DISEASE, 2020, v.11 no.8 , 653-653
    SCIE
  • [학술지논문] Lung-targeted delivery of TGF-beta antisense oligonucleotides to treat pulmonary fibrosis JOURNAL OF CONTROLLED RELEASE, 2020, v.322 no.0 , 108-121
    SCI
  • [학술지논문] Radiation-Induced Lung Fibrosis: Preclinical Animal Models and Therapeutic Strategies CANCERS, 2020, v.12 no.6 , 1561-1561
    SCIE
  • [학술지논문] Specific Roles of HSP27 S15 Phosphorylation Augmenting the Nuclear Function of HER2 to Promote Trastuzumab Resistance CANCERS, 2020, v.12 no.6 , 1-24
    SCIE
  • [학술지논문] Comprehensive analysis of transcriptomic changes induced by low and high doses of bisphenol A in HepG2 spheroids in vitro and rat liver in vivo ENVIRONMENTAL RESEARCH, 2019, v.173 no.0 , 124-134
    SCI
  • [학술지논문] Di-2-ethylhexylphthalate promotes thyroid cell proliferation and DNA damage through activating thyrotropin-receptor-mediated pathways in vitro and in vivo FOOD AND CHEMICAL TOXICOLOGY, 2019, v.124 no.2 , 265-272
    SCI
  • [학술지논문] Radiosensitivity of Cancer Cells Is Regulated by Translationally Controlled Tumor Protein CANCERS, 2019, v.11 no.3 , 386-386
    SCIE
  • [학술지논문] Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation CELL DEATH AND DIFFERENTIATION, 2019, v.26 no.5 , 812-825
    SCI
  • [학술지논문] Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment? CANCERS, 2019, v.11 no.8 , 1195-1195
    SCIE
  • [학술지논문] The Hsp27-Mediated IkB alpha-NF kappa B Signaling Axis Promotes Radiation-Induced Lung Fibrosis CLINICAL CANCER RESEARCH, 2019, v.25 no.17 , 5364-5375
    SCI
강의
  • 2024-2학기

    • 심화실습및연구Ⅰ

      • 학수번호 37154분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅱ

      • 학수번호 37155분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • 심화실습및연구Ⅲ

      • 학수번호 37156분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
    • 생약학Ⅱ

      • 학수번호 38954분반 01
      • 3학년 ( 3학점 , 3시간)
      • 전공필수,원격강의 미래산업약학전공 39059-01반과 합반
    • 생약학Ⅱ

      • 학수번호 39059분반 01
      • 3학년 ( 3학점 , 3시간)
      • 전공필수,원격강의 약학전공 38954-01반과 합반
    • 천연물유래의약품정보

      • 학수번호 G16868분반 01
      • 학년 ( 3학점 , 3시간) 월 6~7 (약)
  • 2024-1학기

    • 천연물약품학

      • 학수번호 37107분반 01
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      • 원격강의 추가 개설, 약학과 38934-01반과 합반
    • 약학실습Ⅳ

      • 학수번호 37127분반 01
      • 4학년 ( 1.5학점 , 3시간) 화 6~9 (약A309)
      • 전공필수 집중이수(8주) 수업, 학번 61~80
    • 약학실습Ⅳ

      • 학수번호 37127분반 02
      • 4학년 ( 1.5학점 , 3시간) 수 6~9 (약A309)
      • 전공필수 집중이수(8주) 수업, 학번 81~100
    • 약학실습Ⅳ

      • 학수번호 37127분반 03
      • 4학년 ( 1.5학점 , 3시간) 월 6~9 (약A309)
      • 전공필수 집중이수(8주) 수업, 학번 101~120
    • 천연물약품학

      • 학수번호 38934분반 01
      • 2학년 ( 3학점 , 3시간)
      • 원격강의
    • 약학실습Ⅰ

      • 학수번호 38963분반 01
      • 3학년 ( 2학점 , 3시간) 월 6~9 (약A309)
      • 전공필수 집중이수(8주) 수업, 약학전공 1~24
    • 약학실습Ⅰ

      • 학수번호 38963분반 02
      • 3학년 ( 2학점 , 3시간) 화 6~9 (약A309)
      • 전공필수 집중이수(8주) 수업, 약학전공 25~48
    • 천연물약품학

      • 학수번호 39039분반 01
      • 2학년 ( 3학점 , 3시간)
      • 원격강의
    • 산업약학입문

      • 학수번호 39045분반 01
      • 2학년 ( 1.5학점 , 1.5시간) 목 6~6 (약A100-1)
    • 약학실습Ⅰ

      • 학수번호 39068분반 01
      • 3학년 ( 2학점 , 3시간) 수 6~9 (약A309)
      • 전공필수 집중이수(8주) 수업, 미래산업약학전공 95~111
  • 2023-2학기

  • 2023-1학기

  • 2022-2학기

    • 생약학II

      • 학수번호 22486분반 01
      • 4학년 ( 3학점 , 3시간) 월 3~3 (약A404) , 수 5~5 (약A404)
      • 전공필수 산업제약학과 02반과 합반
    • 생약학II

      • 학수번호 22486분반 02
      • 4학년 ( 3학점 , 3시간) 월 3~3 (약A404) , 수 5~5 (약A404)
      • 전공필수 약학과 01반과 합반
    • 약학실습Ⅳ

      • 학수번호 37127분반 01
      • 4학년 ( 1.5학점 , 3시간) 월 6~7 (약A309)
      • 전공필수 팀티칭,학번 1~22
    • 약학실습Ⅳ

      • 학수번호 37127분반 02
      • 4학년 ( 1.5학점 , 3시간) 화 6~7 (약A309)
      • 전공필수 팀티칭,학번 23~43
    • 약학실습Ⅳ

      • 학수번호 37127분반 03
      • 4학년 ( 1.5학점 , 3시간) 수 6~7 (약A309)
      • 전공필수 팀티칭,학번 44~65
    • 심화실습및연구Ⅱ

      • 학수번호 37155분반 02
      • 6학년 ( 4학점 , 200시간)
      • 전공필수
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
      • 팀티칭, 산업제약학과 02반과 합반
    • 천연물유래의약품정보

      • 학수번호 G16868분반 01
      • 학년 ( 3학점 , 3시간) 목 5~6 (약)
  • 2022-1학기

    • 천연물약품학

      • 학수번호 37107분반 01
      • 3학년 ( 3학점 , 3시간) 목 7~7 , 금 7~7
      • 원격강의,영어강의 산업제약학 02반과 합반
    • 신약개발세미나및실습III

      • 학수번호 G16849분반 01
      • 학년 ( 3학점 , 3시간) 목 7~8
    • 신약개발세미나및실습Ⅲ

      • 학수번호 G18240분반 01
      • 학년 ( 3학점 , 3시간) 목 7~8
  • 2021-2학기

    • 생약학II

      • 학수번호 22486분반 03
      • 4학년 ( 3학점 , 3시간) 화 3~3 , 금 3~3
      • 전공필수 학번 87-130, 산업제약학과 04반과 합반
    • 생약학II

      • 학수번호 22486분반 04
      • 4학년 ( 3학점 , 3시간) 화 3~3 , 금 3~3
      • 전공필수 약학과 03반과 합반
    • 심화실습및연구Ⅱ

      • 학수번호 37155분반 02
      • 6학년 ( 4학점
      • 전공필수
    • 천연물유래의약품정보

      • 학수번호 G16868분반 01
      • 학년 ( 3학점 , 3시간) 목 2~3
  • 2021-1학기

    • 천연물약품학

      • 학수번호 37107분반 01
      • 3학년 ( 3학점 , 3시간) 화 2~2 , 금 3~3
      • 영어강의 산업제약학 02반과 합반
    • 천연물약품학

      • 학수번호 37107분반 02
      • 3학년 ( 3학점 , 3시간) 화 2~2 , 금 3~3
      • 영어강의 약학과 01반과 합반
    • 약학실습Ⅳ

      • 학수번호 37127분반 01
      • 4학년 ( 1.5학점 , 3시간) 월 6~7 (약A309)
      • 전공필수 팀티칭/ 학번 66~86
    • 약학실습Ⅳ

      • 학수번호 37127분반 02
      • 4학년 ( 1.5학점 , 3시간) 화 6~7 (약A309)
      • 전공필수 팀티칭/ 학번 87~108
    • 약학실습Ⅳ

      • 학수번호 37127분반 03
      • 4학년 ( 1.5학점 , 3시간) 수 6~7 (약A309)
      • 전공필수 팀티칭/ 학번109~130(산업제약학과 04반과 합반)
    • 약학실습Ⅳ

      • 학수번호 37127분반 04
      • 4학년 ( 1.5학점 , 3시간) 수 6~7 (약A309)
      • 전공필수 팀티칭(약학과03반과 합반)
    • Honors research

      • 학수번호 37803분반 01
      • 4학년 ( 1학점 , 1시간)
      • 산업제약학과 02반과 합반
학력

이화여자대학교 약학박사(약학)