EWHA WOMANS UNIVERSITY | Undergraduate/Graduate | Undergraduate | College of Natural Sciences

Jongbum Kwon Professor

Life Sciences/Life Sciences

Professor Jongbum Kwon obtained his Ph.D. from the University of Alabama in Birmingham and did his postdoctoral training at Harvard Medical School. Since appointed as a faculty at Ewha in 2001, his research interest has been mainly focused on understanding the molecular mechanisms governing the genome stability and tumorigenesis. He has published many papers on this topic in high impact SCI journals. He has served as a chief of the Epigenetic and Cell Cycle Sections of the Korean Society for Molecular and Cellular Biology. He is currently an Editorial Board Member of Molecules and Cells and an Advisory Panel Member of the Biochemical Journal (UK).

Science Building C #308
02-3277-4334
Office hours
- 수 4-6, 목 10-12
Research Interests

Research Record

BAP1 as a guardian of genome stability: implications in human cancer Experimental and Molecular Medicine, 2023, v.55 no.4, 745-754
SCIE Scopus KCI dColl.
Targeting BAP1 with small compound inhibitor for colon cancer treatment Scientific Reports, 2023, v.13 no.1, 2264
SCIE Scopus dColl.
BAP1 promotes the repair of UV-induced DNA damage via PARP1-mediated recruitment to damage sites and control of activity and stability Cell Death and Differentiation, 2022
SCIE Scopus dColl.
CHIP and BAP1 Act in Concert to Regulate INO80 Ubiquitination and Stability for DNA Replication MOLECULES AND CELLS, 2021, v.44 no.2, 101-115
SCIE Scopus KCI dColl.
The bromodomain inhibitor PFI-3 sensitizes cancer cells to DNA damage by targeting SWI/SNF Molecular Cancer Research, 2021, v.19 no.5, 900-912
SCIE Scopus dColl.
Cytotoxic activity of bromodomain inhibitor NVS-CECR2-1 on human cancer cells Scientific Reports, 2020, v.10 no.1, 16330
SCIE Scopus dColl.
Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-alpha-Induced Apoptosis via Different Routes CELL REPORTS, 2019, v.26 no.8, 2194-
SCIE Scopus dColl.
BAP1 promotes stalled fork restart and cell survival via INO80 in response to replication stress Biochemical Journal, 2019, v.476 no.20, 3053-3066
SCIE Scopus dColl.
INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis Oncotarget, 2017, v.8 no.70, 115041-115053
SCIE Scopus dColl.
The role of BAP1 and INO80 in genome stability and cancer INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2016, v.38, S38-S38
SCIE Scopus dColl.
ATM-mediated phosphorylation of the chromatin remodeling enzyme BRG1 modulates DNA double-strand break repair ONCOGENE, 2015, v.34 no.3, 351-361
SCIE Scopus dColl.
Targeting BRG1 chromatin remodeler via its bromodomain for enhanced tumor cell radiosensitivity in vitro and in vivo Molecular Cancer Therapeutics, 2015, v.14 no.2, 597-607
SCIE Scopus dColl.
Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation NUCLEIC ACIDS RESEARCH, 2014, v.42 no.2, 1016-1025
SCIE Scopus dColl.
Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis NATURE COMMUNICATIONS, 2014, v.5
SCIE Scopus dColl.
[학술지논문] BAP1 as a guardian of genome stability: implications in human cancer EXPERIMENTAL AND MOLECULAR MEDICINE, 2023, v.55 no.4 , 745-754
SCIE
[학술지논문] Targeting BAP1 with small compound inhibitor for colon cancer treatment SCIENTIFIC REPORTS, 2023, v.13 no.1 , 2264-2264
SCIE
[학술지논문] BAP1 promotes the repair of UV-induced DNA damage via PARP1-mediated recruitment to damage sites and control of activity and stability CELL DEATH AND DIFFERENTIATION, 2022, v.29 no.12 , 2381-2398
SCI
[학술지논문] CHIP and BAP1 Act in Concert to Regulate INO80 Ubiquitination and Stability for DNA Replication MOLECULES AND CELLS, 2021, v.44 no.2 , 101-115
SCI
[학술지논문] The Bromodomain Inhibitor PFI-3 Sensitizes Cancer Cells to DNA Damage by Targeting SWI/SNF MOLECULAR CANCER RESEARCH, 2021, v.19 no.5 , 900-912
SCI
[학술지논문] Cytotoxic activity of bromodomain inhibitor NVS-CECR2-1 on human cancer cells SCIENTIFIC REPORTS, 2020, v.10 no.1 , 16330-16330
SCI
[학술지논문] Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-alpha-Induced Apoptosis via Different Routes CELL REPORTS, 2019, v.26 no.8 , 2194-2194
SCIE
[학술지논문] BAP1 promotes stalled fork restart and cell survival via INO80 in response to replication stress BIOCHEMICAL JOURNAL, 2019, v.476 no.0 , 3053-3066
SCI

2024-1st
- General Biology
  - Subject No 20412Class No 04
  - 1Year ( 3Credit , 3Hour) Mon 5~5 (POSCO453) , Wed 4~4 (POSCO453)
- Molecular Biology Ⅱ
  - Subject No 35825Class No 01
  - 3Year ( 3Credit , 3Hour) Mon 4~4 (POSCO361) , Thu 5~5 (POSCO361)
- Advanced Molecular Biology
  - Subject No G16977Class No 01
  - Year ( 3Credit , 3Hour) Wed 5~6 (SCI-C)
- Cancer Biology
  - Subject No G16978Class No 01
  - Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
2023-2nd
- Molecular Biology I 강의 계획서 상세보기
  - Subject No 20600Class No 01
  - 2Year ( 3Credit , 3Hour) Mon 3~3 (POSCO361) , Wed 2~2 (POSCO361)
- Experiments in Life Sciences II 강의 계획서 상세보기
  - Subject No 35312Class No 01
  - 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA205)
- Experiments in Life Sciences II 강의 계획서 상세보기
  - Subject No 35312Class No 02
  - 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA205)
- Experiments in Life Sciences II 강의 계획서 상세보기
  - Subject No 35312Class No 03
  - 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA205)
- Experiments in Life Sciences II 강의 계획서 상세보기
  - Subject No 35312Class No 04
  - 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA205)
- Experiments in Life Sciences II 강의 계획서 상세보기
  - Subject No 35312Class No 05
  - 2Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA205)
- Introduction to Cancer Biology 강의 계획서 상세보기
  - Subject No 38220Class No 01
  - 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO453) , Fri 5~5 (POSCO453)
- Special Topics in Advanced BiochemistryⅡ
  - Subject No G16949Class No 01
  - Year ( 3Credit , 3Hour) Wed 6~7 (SCI-C)
- Regulation of Gene Manifestation
  - Subject No G16996Class No 01
  - Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
2022-2nd
- Molecular Biology I
  - Subject No 20600Class No 01
  - 2Year ( 3Credit , 3Hour) Mon 2~2 (POSCO361) , Thu 3~3 (POSCO361)
- Experiments in Life Sciences II
  - Subject No 35312Class No 01
  - 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 02
  - 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 03
  - 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 04
  - 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 05
  - 2Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA203)
- Special Topics in Advanced BiochemistryⅡ
  - Subject No G16949Class No 01
  - Year ( 3Credit , 3Hour) Wed 6~7 (SCI-C)
- Regulation of Gene Manifestation
  - Subject No G16996Class No 01
  - Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
2022-1st
- General Biology I
  - Subject No 20413Class No 01
  - 1Year ( 3Credit , 3Hour) Tue 4~4 (POSCO452) , Fri 5~5 (POSCO452)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 01
  - 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA203)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 02
  - 1Year ( 1Credit , 1.5Hour) Tue 6~6 (SCI-AA203)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 03
  - 1Year ( 1Credit , 1.5Hour) Wed 6~6 (SCI-AA203)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 04
  - 1Year ( 1Credit , 1.5Hour) Fri 6~6 (SCI-AA203)
- Molecular Biology II
  - Subject No 35825Class No 01
  - 3Year ( 3Credit , 3Hour) Tue 5~5 (POSCO361) , Thu 6~6 (POSCO361)
- Special Topics in Advanced BiochemistryⅠ
  - Subject No G16948Class No 01
  - Year ( 3Credit , 3Hour) Mon 3~4 (-)
2021-2nd
- Molecular Biology I
  - Subject No 20600Class No 01
  - 2Year ( 3Credit , 3Hour) Mon 2~2 (POSCO451) , Thu 3~3 (POSCO451)
- Experiments in Life Sciences II
  - Subject No 35312Class No 01
  - 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 02
  - 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 03
  - 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 04
  - 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA203)
- Experiments in Life Sciences II
  - Subject No 35312Class No 05
  - 2Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA203)
- Special Topics in Advanced BiochemistryⅡ
  - Subject No G16949Class No 01
  - Year ( 3Credit , 3Hour) Wed 6~7 (SCI-C418)
- Regulation of Gene Manifestation
  - Subject No G16996Class No 01
  - Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
2021-1st
- HOKMA Seminar
  - Subject No 11302Class No 21
  - 1Year ( 1Credit Wed 7~7 (SCI-C303)
- General Biology I
  - Subject No 20413Class No 01
  - 1Year ( 3Credit , 3Hour) Tue 2~2 , Fri 3~3
- General Biology: Laboratory Work I
  - Subject No 33332Class No 01
  - 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA202)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 02
  - 1Year ( 1Credit , 1.5Hour) Tue 6~6 (SCI-AA202)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 03
  - 1Year ( 1Credit , 1.5Hour) Wed 6~6 (SCI-AA202)
- General Biology: Laboratory Work I
  - Subject No 33332Class No 04
  - 1Year ( 1Credit , 1.5Hour) Fri 6~6 (SCI-AA202)
- Molecular Biology II
  - Subject No 35825Class No 01
  - 3Year ( 3Credit , 3Hour) Tue 3~3 (SCI-AA) , Thu 2~2 (102)
- Cancer Biology
  - Subject No G16978Class No 01
  - Year ( 3Credit , 3Hour) Mon 5~6 (SCI-C)

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College of Natural Sciences

Jongbum Kwon Professor

Research Record

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