Eun-Mi Park Professor
College of Medicine/Division of Brain & Cognitive Sciences
Prof. Eun-Mi Park received Ph.D. in Pharmacology at Medical College of Ewha Womans University in 1999 after she got the certification of specialty in neurology. She joined department of neurology of Weil Cornell Medical College as a post-doctoral fellow under the guidance of Drs. Sunghee Cho and Costantino Iadecola from 2000 to 2004. Prof. Park has been appointed as a faculty of department of pharmacology at Medical College of Ewha Womans University since September 2004. The main research theme of Prof. Park is related with molecular biological changes in the brain after experimental ischemic stroke of mice, and she focuses on the mechanisms of tolerance induction, estrogen effects, aging process and BBB permeability. Prof. Park is recruited as a research memeber to Tissue Injury and Defense Research Center (TIDRC) which is supported by National R&D grant by the Korean government to 2019. During recent 5 years, 12 papers from the lab of Prof. Park have been published in Neuroscience field of SCI journals, and 2 of them are published in 'Brain structure & function' and 'Brain Behavior and Immunity' in 2014, respectively.
- Esther Building #413
- 02-6986-6170
- Research Interests
Research Record
- Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult Journal of pharmaceutical and biomedical analysis, 2023, v.224, 115196
- Aging effects on the diurnal patterns of gut microbial composition in male and female mice KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2021, v.25 no.6, 575-583
- Enhanced repair processes and iron uptake by ischemic preconditioning in the brain during the recovery phase after ischemic stroke BRAIN RESEARCH, 2021, v.1750, 147172
- Gas6 Ameliorates Inflammatory Response and Apoptosis in Bleomycin-Induced Acute Lung Injury BIOMEDICINES, 2021, v.9 no.11, 1674
- Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p SCIENTIFIC REPORTS, 2021, v.11 no.1, 12511
- Estrogen deficiency is associated with brain iron deposition via upregulation of hepcidin expression in aged female mice NEUROBIOLOGY OF AGING, 2020, v.96, 33-42
- Interaction of promyelocytic leukemia/p53 affects signal transducer and activator of transcription-3 activity in response to oncostatin M KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2020, v.24 no.3, 203-212
- Motion microscopy for label-free detection of circulating breast tumor cells Biosensors and Bioelectronics, 2020, v.158, 112131
- Gas6 Prevents Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells via Production of PGE(2), PGD(2) and Their Receptors CELLS, 2019, v.8 no.7, 643
- The phosphodiesterase 10 inhibitor papaverine exerts anti-inflammatory and neuroprotective effects via the PKA signaling pathway in neuroinflammation and Parkinson's disease mouse models JOURNAL OF NEUROINFLAMMATION, 2019, v.16 no.1, 246
- A STAT6 Inhibitor AS1517499 Reduces Preventive Effects of Apoptotic Cell Instillation on Bleomycin-Induced Lung Fibrosis by Suppressing PPARy CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, v.45 no.5, 1863-1877
- Aberrant Promoter Hypomethylation of Sortilin 1: A Moyamoya Disease Biomarker JOURNAL OF STROKE, 2018, v.20 no.3, 350-
- Association of blood pressure components with mortality and cardiovascular events in prehypertensive individuals: a nationwide population-based cohort study ANNALS OF MEDICINE, 2018, v.50 no.5, 443-452
- Iron released from reactive microglia by noggin improves myelin repair in the ischemic brain Neuropharmacology, 2018, v.133, 202-215
- Repression of adenosine triphosphate–binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury Neurobiology of Aging, 2018, v.66, 138-148
- Anti-inflammatory mechanism of galangin in lipopolysaccharide-stimulated microglia: Critical role of PPAR-γ signaling pathway Biochemical Pharmacology, 2017, v.144, 120-131
- Concanavalin A Induces Cortical Neuron Apoptosis by Causing ROS Accumulation and Tyrosine Kinase Activation Neurochemical Research, 2017, v.42 no.12, 3504-3514
- Extracellular matrix-derived extracellular vesicles promote cardiomyocyte growth and electrical activity in engineered cardiac atria Biomaterials, 2017, v.146, 49-59
- Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts Oncotarget, 2017, v.8 no.68, 112297-112312
- ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipidmetabolism CARDIOVASCULAR RESEARCH, 2017, v.113 no.10, 1137-1147
- Activation of classical estrogen receptor subtypes reduces tight junction disruption of brain endothelial cells under ischemia/reperfusion injury Free Radical Biology and Medicine, 2016, v.92, 78-89
- Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population Scientific Reports, 2016, v.6
- Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages SCIENTIFIC REPORTS, 2016, v.6
- Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice NEUROBIOLOGY OF AGING, 2016, v.44, 74-84
- Estrogen receptor-mediated resveratrol actions on blood-brain barrier of ovariectomized mice NEUROBIOLOGY OF AGING, 2015, v.36 no.2, 993-1006
- Extracellular signal-regulated kinase1/2-dependent changes in tight junctions after ischemic preconditioning contributes to tolerance induction after ischemic stroke BRAIN STRUCTURE & FUNCTION, 2015, v.220 no.1, 13-26
- MR images of mouse brain using clinical 3T MR scanner and 4CH-Mouse coil JOURNAL OF THE KOREAN PHYSICAL SOCIETY, 2015, v.67 no.1, 237-242
- Visceral adipose tissue inflammation is associated with age-related brain changes and ischemic brain damage in aged mice Brain, Behavior, and Immunity, 2015, v.50
- β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia Journal of Neuroinflammation, 2015, v.12 no.1
- Biochemical Characterization of Eight Genetic Variants of Human DNA Polymerase kappa Involved in Error-Free Bypass across Bulky N-2-Guanyl DNA Adducts CHEMICAL RESEARCH IN TOXICOLOGY, 2014, v.27 no.5, 919-930
- Matrix Metalloproteinase-8 Plays a Pivotal Role in Neuroinflammation by Modulating TNF-alpha Activation JOURNAL OF IMMUNOLOGY, 2014, v.193 no.5, 2384-2393
- Noggin improves ischemic brain tissue repair and promotes alternative activation of microglia in mice Brain, Behavior, and Immunity, 2014, v.40
- RhoA/Phosphatidylinositol 3-Kinase/Protein Kinase B/Mitogen-Activated Protein Kinase Signaling after Growth Arrest-Specific Protein 6/Mer Receptor Tyrosine Kinase Engagement Promotes Epithelial Cell Growth and Wound Repair via Upregulation of Hepatocyte Growth Factor in Macrophages JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, v.350, 563-577
- SHP-2 Binds to Caveolin-1 and Regulates Src Activity via Competitive Inhibition of CSK in Response to H2O2 in Astrocytes PLOS ONE, 2014, v.9 no.3, Article ID e91582
- Transcriptional regulation of adrenomedullin by oncostatin M in human astroglioma cells: Implications for tumor invasion and migration SCIENTIFIC REPORTS, 2014, v.4
- [학술지논문] Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, v.224 no.1 , 115196-115196
- [학술지논문] Aging effects on the diurnal patterns of gut microbial composition in male and female mice KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2021, v.25 no.6 , 575-583
- [학술지논문] Enhanced repair processes and iron uptake by ischemic preconditioning in the brain during the recovery phase after ischemic stroke BRAIN RESEARCH, 2021, v.1750 no.0 , 147172-147172
- [학술지논문] Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p SCIENTIFIC REPORTS, 2021, v.11 no.1 , 12511-12511
- [학술지논문] Estrogen deficiency is associated with brain iron deposition via upregulation of hepcidin expression in aged female mice NEUROBIOLOGY OF AGING, 2020, v.96 no.0 , 33-42
- [학술지논문] The phosphodiesterase 10 inhibitor papaverine exerts anti-inflammatory and neuroprotective effects via the PKA signaling pathway in neuroinflammation and Parkinson's disease mouse models JOURNAL OF NEUROINFLAMMATION, 2019, v.16 no.1 , 246-246
Courses
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2024-1st
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Cardiovascular System
- Subject No 37613Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
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Kidney and Urinary System
- Subject No 37617Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
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Comprehensive Review of Clinical Medicine I
- Subject No 37640Class No 01
- 3Year ( 2Credit , 45Hour)
- Major Requisite
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Aging and Geriatrics
- Subject No G14772Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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Aging and Geriatrics
- Subject No G15690Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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Clinical Pharmacology & Toxicology
- Subject No G15734Class No 01
- Year ( 3Credit , 3Hour) Thu 2~3
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Biological Timing and Chronopharmacology
- Subject No G18650Class No 01
- Year ( 3Credit , 3Hour) Wed 2~3
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2023-2nd
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Principles of Pharmacology
- Subject No 37601Class No 01
- 1Year ( 2Credit , 39Hour)
- Major Requisite
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Infectious Diseases
- Subject No 37607Class No 01
- 1Year ( 3Credit , 63Hour)
- Major Requisite
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Birth, Growth and Development
- Subject No 37623Class No 01
- 2Year ( 3Credit , 62Hour)
- Major Requisite
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Hematology and Oncology
- Subject No 37624Class No 01
- 2Year ( 3Credit , 65Hour)
- Major Requisite
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Molecular Pharmacology
- Subject No G15800Class No 01
- Year ( 3Credit , 3Hour) Thu 2~3
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Pharmacological approach to neuro-regeneration
- Subject No G15803Class No 01
- Year ( 3Credit , 3Hour) Wed 2~3 (-)
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2023-1st
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Cardiovascular System
- Subject No 37613Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
-
Kidney and Urinary System
- Subject No 37617Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
-
Comprehensive Review of Clinical Medicine I
- Subject No 37640Class No 01
- 3Year ( 2Credit , 45Hour)
- Major Requisite
-
Aging and geriatrics
- Subject No G14772Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
-
Aging and Geriatrics
- Subject No G15690Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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2022-2nd
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Principles of Pharmacology
- Subject No 37601Class No 01
- 1Year ( 2Credit , 39Hour)
- Major Requisite
-
Infectious Diseases
- Subject No 37607Class No 01
- 1Year ( 3Credit , 63Hour)
- Major Requisite
-
Birth, Growth and Development
- Subject No 37623Class No 01
- 2Year ( 3Credit , 62Hour)
- Major Requisite
-
Hematology and Oncology
- Subject No 37624Class No 01
- 2Year ( 3Credit , 65Hour)
- Major Requisite
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Advanced Medical Research Practice
- Subject No 38914Class No 01
- 1Year ( 1Credit , 32Hour)
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2022-1st
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Cardiovascular System
- Subject No 37613Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
-
Kidney and Urinary System
- Subject No 37617Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
-
Comprehensive Review of Clinical Medicine I
- Subject No 37640Class No 01
- 3Year ( 2Credit , 45Hour)
- Major Requisite
-
Aging and geriatrics
- Subject No G14772Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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Aging and Geriatrics
- Subject No G15690Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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Molecular mechanisms of substances for brain protection
- Subject No G15738Class No 01
- Year ( 3Credit , 3Hour) Wed 2~3 (-)
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Seminar in PharmacologyⅠ
- Subject No G16532Class No 01
- Year ( 3Credit , 3Hour) Thu 2~3
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2021-2nd
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Principles of Pharmacology
- Subject No 37601Class No 01
- 1Year ( 2Credit , 38Hour)
- Major Requisite
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Infectious Diseases
- Subject No 37607Class No 01
- 1Year ( 3Credit , 63Hour)
- Major Requisite
-
Birth, Growth and Development
- Subject No 37623Class No 01
- 2Year ( 3Credit , 62Hour)
- Major Requisite
-
Hematology and Oncology
- Subject No 37624Class No 01
- 2Year ( 3Credit , 65Hour)
- Major Requisite
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Mechanisms of Neuronal ischemic injury and its experimental models
- Subject No G15804Class No 01
- Year ( 3Credit , 3Hour) Wed 2~3
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The principles of Pharmacology Ⅱ
- Subject No G16533Class No 01
- Year ( 3Credit , 3Hour) Thu 2~3
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2021-1st
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Cardiovascular System
- Subject No 37613Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
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Respiratory System
- Subject No 37614Class No 01
- 2Year ( 3Credit , 63Hour)
- Major Requisite
-
Kidney and Urinary System
- Subject No 37617Class No 01
- 2Year ( 3Credit , 68Hour)
- Major Requisite
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Problem-Based Learning I (PBL I)
- Subject No 37621Class No 01
- 2Year ( 1Credit , 15Hour)
- Major Requisite
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Comprehensive Review of Clinical Medicine I
- Subject No 37640Class No 01
- 3Year ( 2Credit , 45Hour)
- Major Requisite
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Comprehensive Review of Clinical MedicineⅢ
- Subject No 37665Class No 01
- 4Year ( 1Credit , 30Hour)
- Major Requisite
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Aging and geriatrics
- Subject No G14772Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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Aging and Geriatrics
- Subject No G15690Class No 01
- Year ( 3Credit , 3Hour) Thu 7~8
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Principles of Pharmacology I
- Subject No G15733Class No 01
- Year ( 3Credit , 3Hour) Thu 2~3
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Drug transport via Blood-brain barrier
- Subject No G15737Class No 01
- Year ( 3Credit , 3Hour) Wed 2~3
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Academic Background
Ewha Womans University 의학박사(의학과)