Sun-Shin Cha Professor
Chemistry & Nanoscience
- Science Building A #A412
- 02-3277-3858
- Research Interests
Research Record
- A novel splicing variant of DJ-1 in Parkinson's disease induces mitochondrial dysfunction Heliyon, 2023, v.9 no.3, e14039
- An archaeal transcription factor EnfR with a novel ‘eighth note’ fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1 Nucleic Acids Research, 2023, v.51 no.18, 10026-10040
- DJ-1 promotes cell migration by interacting with Mena, the mammalian homolog of Drosophila enabled Advances in Biological Regulation, 2023, v.88, 100943
- Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy THERANOSTICS, 2023, v.13 no.14, 5075-5098
- Heating-mediated purification of active FGF21 and structure-based design of its variant with enhanced potency Scientific Reports, 2023, v.13 no.1, 1005
- Structural and functional characterization of a thermostable secretory phospholipase A2 from Sciscionella marina and its application in liposome biotransformation Acta crystallographica. Section D, Structural biology, 2023, v.79, 188-197
- Targeting BAP1 with small compound inhibitor for colon cancer treatment Scientific Reports, 2023, v.13 no.1, 2264
- Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces sp JOURNAL OF ANTIBIOTICS, 2022, v.75 no.11, 619-625
- Engineering of a bacterial outer membrane vesicle to a nano-scale reactor for the biodegradation of β-lactam antibiotics Journal of Biotechnology, 2022, v.356, 1-7
- Expression and purification of intracrine human FGF 11 and study of its FGFR-dependent biological activity JOURNAL OF MICROBIOLOGY, 2022, v.60 no.11, 1086-1094
- Folic acid pretreatment and its sustained delivery for chondrogenic differentiation of MSCs Journal of Controlled Release, 2022, v.343, 118-130
- Improvement of FGF7 Thermal Stability by Introduction of Mutations in Close Vicinity to Disulfide Bond and Surface Salt Bridge International Journal of Peptide Research and Therapeutics, 2022, v.28 no.3, 85
- Pralatrexate Sustainably Released from Polypeptide Thermogel Is Effective for Chondrogenic Differentiation of Mesenchymal Stem Cells ACS Applied Materials and Interfaces, 2022, v.14 no.3, 3773-3783
- Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp. MARINE DRUGS, 2022, v.20 no.1, 35
- Structural and functional identification of the uncharacterized metallo-β-lactamase superfamily protein TW9814 as a phosphodiesterase with unique metal coordination Acta Crystallographica Section D: Structural Biology, 2022, v.78, 532-541
- The Analyses of Cetacean Virus-Responsive Genes Reveal Evolutionary Marks in Mucosal Immunity-Associated Genes Biochemical Genetics, 2022
- Antibacterial Meroterpenoids, Merochlorins G-J from the Marine Bacterium Streptomyces sp. MARINE DRUGS, 2021, v.19 no.11, 618
- Crystal structure of AmpC BER and molecular docking lead to the discovery of broad inhibition activities of halisulfates against β-lactamases Computational and Structural Biotechnology Journal, 2021, v.19, 145-152
- Dj-1 can replace fgf-2 for long-term culture of human pluripotent stem cells in defined media and feeder-free condition International Journal of Molecular Sciences, 2021, v.22 no.11, 5954
- Gold nanoparticle-assisted SELEX as a visual monitoring platform for the development of small molecule-binding DNA aptasensors Biosensors and Bioelectronics, 2021, v.191, 113468
- Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells CANCERS, 2021, v.13 no.14, 3418
- Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms Nature Communications, 2021, v.12 no.1, 5931
- Structural basis of the cooperative activation of type II citrate synthase (HyCS) from Hymenobacter sp. PAMC 26554 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, v.183, 213-221
- Novel inhibition mechanism of carbapenems on the ACC-1 class C β-lactamase Archives of Biochemistry and Biophysics, 2020, v.693, 108570
- Novel short peptide tag from a bacterial toxin for versatile applications JOURNAL OF IMMUNOLOGICAL METHODS, 2020, v.479, UNSP 112750
- Structural and biochemical analyses of an aminoglycoside 2 '-N-acetyltransferase from Mycolicibacterium smegmatis SCIENTIFIC REPORTS, 2020 , 21503
- Complete reconstitution of the diverse pathways of gentamicin B biosynthesis Nature Chemical Biology, 2019, v.15 no.3, 295-303
- Structural Insights into Catalytic Relevances of Substrate Poses in ACC-1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2019, v.63 no.11, e01411-19
- Structural basis of small RNA hydrolysis by oligoribonuclease (CpsORN) from Colwellia psychrerythraea strain 34H Scientific Reports, 2019, v.9 no.1, 2649
- Water-Soluble Phthalocyanines Selectively Bind to Albumin Dimers: A Green Approach Toward Enhancing Tumor-Targeted Photodynamic Therapy THERANOSTICS, 2019, v.9 no.22, 6412-6423
- In vitro and in vivo Inhibitory Activity of NADPH Against the AmpC BER Class C beta-Lactamase FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2018, v.8, 441
- Inhibitory effect of tartrate against phosphate-induced DJ-1 aggregation INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, v.107, 1650-1658
- Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, v.66 no.40, 10608-10616
- Structural basis for the interaction between DJ-1 and Bcl-X-L BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, v.495 no.1, 1067-1073
- Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans SCIENTIFIC REPORTS, 2017, v.7
- Biosynthetic pathways of aminoglycosides and their engineering Current Opinion in Biotechnology, 2017, v.48, 33-41
- Catalytic Intermediate Crystal Structures of Cysteine Desulfurase from the Archaeon Thermococcus onnurineus NA1 ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL, 2017
- GMP and IMP are competitive inhibitors of CMY-10, an extended-spectrum class C β-lactamase Antimicrobial Agents and Chemotherapy, 2017, v.61 no.5
- Genetic and Structural Characterization of a Thermo-Tolerant, Cold-Active, and Acidic Endo-beta-1,4-glucanase from Antarctic Springtail, Cryptopygus antarcticus JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, v.65 no.8, 1630-1640
- Genetic and Structural Characterization of a Thermo-Tolerant, Cold-Active, and Acidic Endo-β-1,4-glucanase from Antarctic Springtail, Cryptopygus antarcticus Journal of Agricultural and Food Chemistry, 2017, v.65 no.8, 1630-1640
- Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium Nature Communications, 2017, v.8 no.1
- Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017, v.72 no.3, 735-743
- Zinc-dependent regulation of zinc import and export genes by Zur NATURE COMMUNICATIONS, 2017, v.8
- Biophysical characterization of the structural change of Nopp140, an intrinsically disordered protein, in the interaction with CK2α Biochemical and Biophysical Research Communications, 2016, v.477 no.2, 181-187
- Cross-protection against Vibrio cholerae infection by monoclonal antibodies against Vibrio vulnificus RtxA1/MARTXVv Microbiology and Immunology, 2016, v.60 no.11, 793-800
- Crystal Structures of Peptide Deformylase from Rice Pathogen Xanthomonas oryzae pv. oryzae in Complex with Substrate Peptides, Actinonin, and Fragment Chemical Compounds JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2016, v.64 no.39, 7307-7314
- Identification of a Highly Conserved Hypothetical Protein TON_0340 as a Probable Manganese-Dependent Phosphatase PLOS ONE, 2016, v.11 no.12
- Purification, crystallization, and preliminary X-ray crystallographic analysis of the Group III chaperonin from Carboxydothermus hydrogenoformans JOURNAL OF MICROBIOLOGY, 2016, v.54 no.6, 440-444
- Structural basis for the extended substrate spectrum of AmpC BER and structure-guided discovery of the inhibition activity of citrate against the class C beta-lactamases AmpC BER and CMY-10 ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2016, v.72, 976-985
- Structural basis for the ATP-independent proteolytic activity of LonB proteases and reclassification of their AAA plus modules JOURNAL OF MICROBIOLOGY, 2015, v.53 no.10, 711-717
- The crystal structure of the D-alanine-D-alanine ligase from Acinetobacter baumannii suggests a flexible conformational change in the central domain before nucleotide binding JOURNAL OF MICROBIOLOGY, 2015, v.53 no.11, 776-782
- [학술지논문] Crystal structure of AmpC BER and molecular docking lead to the discovery of broad inhibition activities of halisulfates against beta-lactamases COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, v.19 no.0 , 145-152
- [학술지논문] Structural and biochemical analyses of an aminoglycoside 2 '-N-acetyltransferase from Mycolicibacterium smegmatis SCIENTIFIC REPORTS, 2020, v.10 no.1 , 21503-21503
Courses
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2024-1st
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First-Year Seminar
- Subject No 10851Class No 09
- 1Year ( 1Credit Mon 7~7
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Biochemistry Ⅰ
- Subject No 30126Class No 01
- 3Year ( 3Credit , 3Hour) Tue 3~3 (SCI-) , Thu 2~2 (101)
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Advanced Chemical Biology
- Subject No G15647Class No 01
- Year ( 3Credit , 3Hour) Wed 5~6 (-D108)
- Class Hour Changed
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2023-2nd
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General Chemistry Ⅱ
- Subject No 20417Class No 02
- 1Year ( 3Credit , 3Hour) Mon 5~5 (POSCO453) , Wed 4~4 (POSCO453)
- Taking this course with General Chemistry is not allowed
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Biochemistry II 강의 계획서 상세보기
- Subject No 30127Class No 01
- 3Year ( 3Credit , 3Hour) Mon 4~4 (SCI-AA) , Thu 5~5 (101)
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Advanced Biochemistry
- Subject No G12383Class No 01
- Year ( 3Credit , 3Hour) Thu 3~4 (D106)
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2023-1st
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HOKMA Seminar 강의 계획서 상세보기
- Subject No 11302Class No 18
- 1Year ( 1Credit Mon 7~7 (SCI-AA412)
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General Chemistry I
- Subject No 20416Class No 02
- 1Year ( 3Credit , 3Hour) Tue 5~5 (SCI-AA) , Thu 6~6 (101)
-
Biochemistry I 강의 계획서 상세보기
- Subject No 30126Class No 01
- 3Year ( 3Credit , 3Hour) Tue 3~3 (SCI-) , Thu 2~2 (101)
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Methods for Biochemical Researches
- Subject No G12616Class No 01
- Year ( 3Credit , 3Hour) Thu 2~3 (D108)
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2021-2nd
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General Chemistry II
- Subject No 20417Class No 02
- 1Year ( 3Credit , 3Hour) Mon 2~2 , Thu 3~3
- Taking this course with General Chemistry is not allowed
-
Biochemistry II
- Subject No 30127Class No 01
- 3Year ( 3Credit , 3Hour) Tue 2~2 , Fri 3~3
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Advanced Biochemistry
- Subject No G12383Class No 01
- Year ( 3Credit , 3Hour) Tue 4~5 (D106)
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2021-1st
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First-Year Seminar
- Subject No 10851Class No 07
- 1Year ( 1Credit Mon 7~7 (SCI-AA412)
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General Chemistry : Laboratory Work I
- Subject No 20418Class No 04
- 1Year ( 1Credit , 1.5Hour) Thu 6~6 (SCI-)
- Exchange students not allowed. This course may last until 7th class
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General Chemistry : Laboratory Work I
- Subject No 20418Class No 05
- 1Year ( 1Credit , 1.5Hour) Fri 6~6 (SCI-)
- Exchange students not allowed. This course may last until 7th class
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General Chemistry : Laboratory Work I
- Subject No 20418Class No 06
- 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-)
- Exchange students not allowed. This course may last until 7th class
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Biochemistry I
- Subject No 30126Class No 01
- 3Year ( 3Credit , 3Hour) Tue 4~4 , Fri 5~5
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Advanced Chemical Biology
- Subject No G15647Class No 01
- Year ( 3Credit , 3Hour) Tue 5~6 (D109)
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