Wan Kyu Kim Professor
Life Sciences/Life Sciences
Wankyu Kim received his PhD in Bioinformatics from the University of Cambridge in 2007. He is interested in diverse aspects of bioinformatics and systems biology including miRNA, chemical genomics, drug informatics, cancer genomics, and network biology. He developed many bioinformatic tools and published more than 25 scientific papers.
- Department Chair, Bio-Information Science/Department Chair, Bioinformatics
- Science Building A #A208
- 02-3277-4132
Research Record
- Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer Molecular Cancer, 2018, v.17 no.1, 175
- BEAR: A Novel Virtual Screening Method Based on Large-Scale Bioactivity Data JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, v.63 no.5
- NecroX Improves Polyhexamethylene Guanidine-induced Lung Injury by Regulating Mitochondrial Oxidative Stress and Endoplasmic Reticulum Stress American journal of respiratory cell and molecular biology, 2023, v.69 no.1, 57-72
- Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trial Clinical and Molecular Hepatology, 2022, v.28 no.3, 497-509
- Circulating Small Extracellular Vesicles Activate TYRO3 to Drive Cancer Metastasis and Chemoresistance CANCER RESEARCH, 2021, v.81 no.13, 3539-3553
- Comprehensive Survey of Recent Drug Discovery Using Deep Learning INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, v.22 no.18, 9983
- Enhanced Sensitivity of Nonsmall Cell Lung Cancer with Acquired Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors to Phenformin: The Roles of a Metabolic Shift to Oxidative Phosphorylation and Redox Balance Oxidative Medicine and Cellular Longevity, 2021, v.2021, 5428364
- Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer Oncogene, 2020, v.39 no.23, 4567-4580
- Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation Proceedings of the National Academy of Sciences of the United States of America, 2020, v.117 no.33, 19982-19993
- MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer Scientific Reports, 2020, v.10 no.1, 2833
- Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis EXPERIMENTAL AND MOLECULAR MEDICINE, 2020 , 1831-1844
- Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation Nature Communications, 2020, v.11 no.1, 4343
- Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance Biomaterials, 2020, v.262, 120295
- Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis Redox Biology, 2020, v.37, 101719
- CDRgator: An Integrative Navigator of Cancer Drug Resistance Gene Signatures Molecules and cells, 2019, v.42 no.3, 237-244
- CSgator: an integrated web platform for compound set analysis JOURNAL OF CHEMINFORMATICS, 2019, v.11, 17
- Comparison of Target Features for Predicting Drug-Target Interactions by Deep Neural Network Based on Large-Scale Drug-Induced Transcriptome Data PHARMACEUTICS, 2019, v.11 no.8, 377
- In silico drug repositioning: from large-scale transcriptome data to therapeutics ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42 no.10, 879-889
- Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells FRONTIERS IN CHEMISTRY, 2019, v.7, 298
- Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway SCIENTIFIC REPORTS, 2018, v.8, 12407
- Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics STEM CELL REPORTS, 2018, v.11 no.5, 1244-1256
- Drug Repositioning for Cancer Therapy Based on Large-Scale Drug-Induced Transcriptional Signatures PLOS ONE, 2016, v.11 no.3
- Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway Nature Communications, 2016, v.7
- A Novel Human scFv Library with Non-Combinatorial Synthetic CDR Diversity PLOS ONE, 2015, v.10 no.10, e0141045
- miRseqViewer: multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing data BIOINFORMATICS, 2015, v.31 no.4, 596-598
- A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma NATURE GENETICS, 2014, v.46 no.4, 371-
- Exome and transcriptome profiling of lung adenocarcinoma in female never-smokers CANCER RESEARCH, 2014, v.74 no.19
- GEPdb: a database for investigating the ternary association of genotype, gene expression and phenotype BIOINFORMATICS, 2014, v.30 no.17, 2540-2542
- IncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs BIOINFORMATICS, 2014, v.30 no.17, 2480-2485
- gsGator : an integrated web platform for cross-species gene set analysis BMC BIOINFORMATICS, 2014, v.15, 13
- [학술지논문] SARS-CoV-2 infection in severe asthma is associated with worsening of COVID-19 through respiratory NLRP3 inflammasome activation ALLERGY, 2023, v.10 no.1111 , 15452-15452
- [학술지논문] Targeting Na-H exchanger 1 overcomes nuclear factor kappa B-mediated tumor resistance to radiotherapy NEOPLASIA, 2023, v.35 no.1 , 100862-100862
- [학술지논문] Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trial Clinical and molecular hepatology, 2022, v.28 no.3 , 497-509
- [학술지논문] Crosstalk between YAP and TGF beta regulates SERPINE1 expression in mesenchymal lung cancer cells INTERNATIONAL JOURNAL OF ONCOLOGY, 2021, v.58 no.1 , 111-121
- [학술지논문] Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, v.117 no.33 , 19982-19993
- [학술지논문] MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer SCIENTIFIC REPORTS, 2020, v.10 no.1 , 2833-2833
- [학술지논문] Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis EXPERIMENTAL AND MOLECULAR MEDICINE, 2020, v.52 no.11 , 1831-1844
- [학술지논문] Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation NATURE COMMUNICATIONS, 2020, v.11 no.1 , 4343-4343
- [학술지논문] CDRgator: An Integrative Navigator of Cancer Drug Resistance Gene Signatures MOLECULES AND CELLS, 2019, v.42 no.3 , 237-244
- [학술지논문] CSgator: an integrated web platform for compound set analysis JOURNAL OF CHEMINFORMATICS, 2019, v.11 no.0 , 17-17
- [학술지논문] Comparison of Target Features for Predicting Drug-Target Interactions by Deep Neural Network Based on Large-Scale Drug-Induced Transcriptome Data PHARMACEUTICS, 2019, v.11 no.8 , 377-377
- [학술지논문] In silico drug repositioning: from large-scale transcriptome data to therapeutics ARCHIVES OF PHARMACAL RESEARCH, 2019, v.42 no.10 , 879-889
- [학술지논문] Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells FRONTIERS IN CHEMISTRY, 2019, v.7 no.0 , 298-298
- [학술발표] http://new.ksbmb.or.kr/academic_events_etc/academic_evt_main.php KSBMB International Conference 2019, 대한민국, 제주, 2019-06-04 KSBMB International Conference 2019, 2019
Courses
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2023-1st
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First-Year Seminar 강의 계획서 상세보기
- Subject No 10851Class No 15
- 1Year ( 1Credit Mon 7~7
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General Biology: Laboratory Work I 강의 계획서 상세보기
- Subject No 33332Class No 01
- 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA203)
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General Biology: Laboratory Work I 강의 계획서 상세보기
- Subject No 33332Class No 02
- 1Year ( 1Credit , 1.5Hour) Wed 6~6 (SCI-AA203)
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General Biology: Laboratory Work I 강의 계획서 상세보기
- Subject No 33332Class No 03
- 1Year ( 1Credit , 1.5Hour) Thu 6~6 (SCI-AA203)
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General Biology: Laboratory Work I 강의 계획서 상세보기
- Subject No 33332Class No 04
- 1Year ( 1Credit , 1.5Hour) Fri 6~6 (SCI-AA203)
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Molecular Biology II 강의 계획서 상세보기
- Subject No 35825Class No 02
- 3Year ( 3Credit , 3Hour) Mon 4~4 (POSCO362) , Thu 5~5 (POSCO362)
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Bio Big Data Mining 강의 계획서 상세보기
- Subject No 36338Class No 01
- 4Year ( 3Credit , 3Hour) Tue 4~4 (POSCO361) , Fri 5~5 (POSCO361)
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Life Science SeminarⅢ
- Subject No G16930Class No 01
- Year ( 3Credit , 3Hour) Thu 3~4 (SCI-C)
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2022-2nd
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Molecular Biology I
- Subject No 20600Class No 03
- 2Year ( 3Credit , 3Hour) Mon 2~2 (POSCO362) , Thu 3~3 (POSCO362)
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Experiments in Life Sciences II
- Subject No 35312Class No 01
- 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 02
- 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 03
- 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 04
- 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 05
- 2Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA203)
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Integrative Biology SeminarⅡ
- Subject No G16967Class No 01
- Year ( 3Credit , 3Hour) Mon 3~4 (SCI-C515)
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2022-1st
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General Biology: Laboratory Work I
- Subject No 33332Class No 01
- 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA203)
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General Biology: Laboratory Work I
- Subject No 33332Class No 02
- 1Year ( 1Credit , 1.5Hour) Tue 6~6 (SCI-AA203)
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General Biology: Laboratory Work I
- Subject No 33332Class No 03
- 1Year ( 1Credit , 1.5Hour) Wed 6~6 (SCI-AA203)
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General Biology: Laboratory Work I
- Subject No 33332Class No 04
- 1Year ( 1Credit , 1.5Hour) Fri 6~6 (SCI-AA203)
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Molecular Biology II
- Subject No 35825Class No 03
- 3Year ( 3Credit , 3Hour) Tue 5~5 , Thu 6~6
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System Biology
- Subject No 36338Class No 01
- 4Year ( 3Credit , 3Hour) Tue 3~3 , Thu 2~2
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Advanced Molecular Biology
- Subject No G16977Class No 01
- Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
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2021-2nd
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Molecular Biology I
- Subject No 20600Class No 03
- 2Year ( 3Credit , 3Hour) Mon 2~2 (POSCO453) , Thu 3~3 (POSCO453)
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Experiments in Life Sciences II
- Subject No 35312Class No 01
- 2Year ( 2Credit , 3Hour) Mon 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 02
- 2Year ( 2Credit , 3Hour) Tue 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 03
- 2Year ( 2Credit , 3Hour) Wed 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 04
- 2Year ( 2Credit , 3Hour) Thu 6~7 (SCI-AA203)
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Experiments in Life Sciences II
- Subject No 35312Class No 05
- 2Year ( 2Credit , 3Hour) Fri 6~7 (SCI-AA203)
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Genome Informatics
- Subject No G17016Class No 01
- Year ( 3Credit , 3Hour) Mon 3~4 (SCI-C-515)
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2021-1st
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Introductory Biology
- Subject No 10066Class No 01
- Year ( 3Credit , 3Hour) Tue 3~3 , Fri 3~3
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General Biology: Laboratory Work I
- Subject No 33332Class No 01
- 1Year ( 1Credit , 1.5Hour) Mon 6~6 (SCI-AA202)
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General Biology: Laboratory Work I
- Subject No 33332Class No 02
- 1Year ( 1Credit , 1.5Hour) Tue 6~6 (SCI-AA202)
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General Biology: Laboratory Work I
- Subject No 33332Class No 03
- 1Year ( 1Credit , 1.5Hour) Wed 6~6 (SCI-AA202)
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General Biology: Laboratory Work I
- Subject No 33332Class No 04
- 1Year ( 1Credit , 1.5Hour) Fri 6~6 (SCI-AA202)
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Molecular Biology II
- Subject No 35825Class No 03
- 3Year ( 3Credit , 3Hour) Tue 3~3 (POSCO453) , Thu 2~2 (POSCO453)
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System Biology
- Subject No 36338Class No 01
- 4Year ( 3Credit , 3Hour) Mon 3~3 (POSCO363) , Wed 2~2 (POSCO363)
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Advanced Molecular Biology
- Subject No G16977Class No 01
- Year ( 3Credit , 3Hour) Tue 5~6 (SCI-C)
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Academic Background
University of Cambridge Ph.D.(생명정보학)
Seoul Nat'l Univ. 이학석사(미생물학과)
Seoul Nat'l Univ. 이학사(미생물학과)