EWHA WOMANS UNIVERSITY | Undergraduate/Graduate | Undergraduate | College of Medicine

Seonghee Park Assistant Professor

College of Medicine

Seonghee Park is a professor of Department of Physiology at Ewha Medical School. Her research interest is the mechanistic basis of channelopathy and its relationship to the various human diseases from levels of single channel to animal models or human samples by integrative and multidisciplinary approaches; 1) Mechanisms of epithelial fluid and electrolyte transport, 2) Mechanisms of lipotoxicity-induced vascular dysfunction

Chair, Department of Physiology
Esther Building #404
02-6986-6181

Research Record

Inhibition of p90RSK Ameliorates PDGF-BB-Mediated Phenotypic Change of Vascular Smooth Muscle Cell and Subsequent Hyperplasia of Neointima International Journal of Molecular Sciences, 2023, v.24 no.9, 8094
SCIE Scopus dColl.
Lyso-globotriaosylsphingosine induces endothelial dysfunction via autophagy-dependent regulation of necroptosis Korean Journal of Physiology and Pharmacology, 2023, v.27 no.3, 231-240
SCIE Scopus KCI dColl.
[학술지논문] Inhibition of p90RSK Ameliorates PDGF-BB-Mediated Phenotypic Change of Vascular Smooth Muscle Cell and Subsequent Hyperplasia of Neointima INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, v.24 no.9 , 1-1
SCIE
[학술지논문] Lyso-globotriaosylsphingosine induces endothelial dysfunction via autophagy-dependent regulation of necroptosis KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2023, v.27 no.3 , 231-240
SCIE
[학술지논문] Long pentraxin PTX3 mediates acute inflammatory responses against pneumococcal infection BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, v.493 no.1 , 671-676
SCI
[학술지논문] Orai1 and STIM1 in ER/PM junctions: roles in pancreatic cell function and dysfunction AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, v.310 no.6 , 414-422
SCI
[학술지논문] Role of protein kinase A and class II phosphatidylinositol 3-kinase C2 beta in the downregulation of KCa3.1 channel synthesis and membrane surface expression by lyso-globotriaosylceramide BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, v.470 no.4 , 907-912
SCI
[학술지논문] Lyso-globotriaosylceramide downregulates KCa3.1 channel expression to inhibit collagen synthesis in fibroblasts BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, v.468 no.4 , 883-888
SCI
[학술지논문] The ER/PM microdomain, PI(4,5)P-2 and the regulation of STIM1-Orai1 channel function CELL CALCIUM, 2015, v.58 no.4 , 342-348
SCI
[학술지논문] Globotriaosylceramide Induces Lysosomal Degradation of Endothelial K(Ca)3.1 in Fabry Disease ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2014, v.34 no.1 , 81-100
SCI
[학술지논문] Mechanism and synergism in epithelial fluid and electrolyte secretion PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2014, v.466 no.8 , 1487-1499
SCI
[학술지논문] cAMP and Ca2+ signaling in secretory epithelia: Crosstalk and synergism CELL CALCIUM, 2014, v.55 no.6 , 385-393
SCI
[학술지논문] Irbit Mediates Synergy Between Ca2+ and cAMP Signaling Pathways During Epithelial Transport in Mice GASTROENTEROLOGY, 2013, v.145 no.1 , 232-241
SCI
[학술지논문] NADPH oxidase 2-derived superoxide downregulates endothelial K(Ca)3.1 in preeclampsia FREE RADICAL BIOLOGY AND MEDICINE, 2013, v.57 no.0 , 10-21
SCI
[학술지논문] Modafinil inhibits K(Ca)3.1 currents and muscle contraction via a cAMP-dependent mechanism PHARMACOLOGICAL RESEARCH, 2012, v.66 no.1 , 51-59
SCI
[학술지논문] The WNK/SPAK and IRBIT/PP1 Pathways in Epithelial Fluid and Electrolyte Transport PHYSIOLOGY, 2012, v.27 no.5 , 291-299
SCI
[학술지논문] Globotriaosylceramide leads to K(Ca)3.1 channel dysfunction: a new insight into endothelial dysfunction in Fabry disease CARDIOVASCULAR RESEARCH, 2011, v.89 no.2 , 290-299
SCI
[학술지논문] Modulation of nonselective cation current by oxidized LDL and lysophosphatidylcholine and its inhibitory contribution to endothelial damage LIFE SCIENCES, 2010, v.86 no.19-20 , 733-739
SCI
[학술지논문] SUPEROXIDE IS A POTENTIAL CULPRIT OF CASPASE-3 DEPENDENT ENDOTHELIAL CELL DEATH INDUCED BY LYSOPHOSPHATIDYLCHOLINE JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2010, v.61 , 375-381
SCI
[학술지논문] Superoxide Generated by Lysophosphatidylcholine Induces Endothelial Nitric Oxide Synthase Downregulation in Human Endothelial Cells CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2010, v.25 no.2-3 , 233-240
SCI
[학술지논문] STIMULATION OF LARGE-CONDUCTANCE Ca2+-ACTIVATED K+ CHANNELS BY THE Na+/Ca2+ EXCHANGER INHIBITOR DICHLOROBENZAMIL IN CULTURED HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND MOUSE AORTIC SMOOTH MUSCLE CELLS JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2009, v.60 , 43-50
SCI
[학술지논문] Intracellular Na+ modulates large conductance Ca2+-activated K+ currents in human umbilical vein endothelial cells PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2008, v.457 , 67-75
SCI
[저역서] Calcium Entry Pathways in Non-excitable Cells (Advances in Experimental Medicine and Biology) Springer International Publishing, 2016, 471

2024-1st
- Molecular Cell Biology Ⅰ 강의 계획서 상세보기
  - Subject No 34353Class No 01
  - 2Year ( 3Credit , 3Hour) Fri 4~5 (D)
  - Major Requisite
- Introduction to Medicine
  - Subject No 37588Class No 01
  - 1Year ( 2.5Credit , 48Hour)
  - Major Requisite
- Human Histology and PhysiologyⅠ
  - Subject No 37592Class No 01
  - 1Year ( 3Credit , 57Hour)
  - Major Requisite
- Human Histology and PhysiologyⅡ
  - Subject No 37593Class No 01
  - 1Year ( 2Credit , 44Hour)
  - Major Requisite
- Metabolism and Nutrition
  - Subject No 37594Class No 01
  - 1Year ( 2.5Credit , 52Hour)
  - Major Requisite
2023-2nd
- Structure and Function of the Human Nervous System
  - Subject No 37600Class No 01
  - 1Year ( 3.5Credit , 70Hour)
  - Major Requisite
2023-1st
- Molecular Cell Biology Ⅰ 강의 계획서 상세보기
  - Subject No 34353Class No 01
  - 2Year ( 3Credit , 3Hour) Fri 4~5 (D)
  - Major Requisite
- Introduction to Medicine
  - Subject No 37588Class No 01
  - 1Year ( 2.5Credit , 48Hour)
  - Major Requisite
- Human Histology and PhysiologyⅠ
  - Subject No 37592Class No 01
  - 1Year ( 3Credit , 57Hour)
  - Major Requisite
- Human Histology and PhysiologyⅡ
  - Subject No 37593Class No 01
  - 1Year ( 2Credit , 44Hour)
  - Major Requisite
- Metabolism and Nutrition
  - Subject No 37594Class No 01
  - 1Year ( 2.5Credit , 52Hour)
  - Major Requisite
- Seminars in Biomedical Science I
  - Subject No G14773Class No 01
  - Year ( 3Credit , 3Hour) Mon 7~8
- Seminars in Biomedical Science III
  - Subject No G14774Class No 01
  - Year ( 3Credit , 3Hour) Mon 7~8
- Seminars in Biomedical Science I
  - Subject No G15691Class No 01
  - Year ( 3Credit , 3Hour) Mon 7~8
- Seminars in Biomedical Science III
  - Subject No G15692Class No 01
  - Year ( 3Credit , 3Hour) Mon 7~8
2022-2nd
- Structure and Function of the Human Nervous System
  - Subject No 37600Class No 01
  - 1Year ( 3.5Credit , 70Hour)
  - Major Requisite
2022-1st
- Molecular Cell Biology Ⅰ
  - Subject No 34353Class No 01
  - 2Year ( 3Credit , 3Hour) Fri 3~4
  - Major Requisite
- Introduction to Medicine
  - Subject No 37588Class No 01
  - 1Year ( 2.5Credit , 48Hour)
  - Major Requisite
- Human Histology and PhysiologyⅠ
  - Subject No 37592Class No 01
  - 1Year ( 3Credit , 57Hour)
  - Major Requisite
- Human Histology and PhysiologyⅡ
  - Subject No 37593Class No 01
  - 1Year ( 2Credit , 44Hour)
  - Major Requisite
- Metabolism and Nutrition
  - Subject No 37594Class No 01
  - 1Year ( 2.5Credit , 52Hour)
  - Major Requisite
2021-2nd
- Structure and Function of the Human Nervous System
  - Subject No 37600Class No 01
  - 1Year ( 3.5Credit , 70Hour)
  - Major Requisite
2021-1st
- Introduction to Medicine
  - Subject No 37588Class No 01
  - 1Year ( 2.5Credit , 48Hour)
  - Major Requisite
- Human Histology and PhysiologyⅠ
  - Subject No 37592Class No 01
  - 1Year ( 3Credit , 57Hour)
  - Major Requisite
- Human Histology and PhysiologyⅡ
  - Subject No 37593Class No 01
  - 1Year ( 2Credit , 45Hour)
  - Major Requisite
- Metabolism and Nutrition
  - Subject No 37594Class No 01
  - 1Year ( 2.5Credit , 52Hour)
  - Major Requisite

Academic Background

Ewha Womans University 의학박사(의학)

List

College of Medicine

Seonghee Park Assistant Professor

Research Record

Courses

Academic Background