Hyung-Lae Kim Professor Emeritus
Dr Hyung-Lae Kim is a professor of the Department of Biochemistry, School of Medicine. His reseach field is the medical genomics, and he has experineces in the establishment of strategy and plannning for long-term biomedical reseach. He got the MD and PhD degrees in Seoul National University. His reseach has focused on the genetic and epidemiological understanding of obesity and common disease, and the development of intervention tools to control such disease. He was the director Director:Ewha Global Challenge of Medicine, BK21 Korea Program, Ministry of Education, in 2006. He seved as a government officer, as Director General of Korea National Institute of Heath, Ministry of Health and Welfare until 2010. In academic filed, he was Co-president,: Korean HapMap Consortium, the President of Korean Genome Organization, and the President of Korean Society of Biochemstry and Molocular Biology, at 2011 and 2013, respectively. He published more than 90 peer reviewed sciectific papers.
- Research Interests
Research Record
- Association between gut microbiota and anxiety symptoms: A large population-based study examining sex differences Journal of Affective Disorders, 2023, v.333, 21-29
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids AMERICAN JOURNAL OF HUMAN GENETICS, 2022, v.109 no.8, 1366-1387
- Association Between Gut Microbiota and Depressive Symptoms: A Cross-Sectional Population-Based Study in South Korea Psychosomatic Medicine, 2022, v.84 no.7, 757-765
- Gut microbiota and the prevalence and incidence of renal stones Scientific Reports, 2022, v.12 no.1, 3732
- Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis Genome Biology, 2022, v.23 no.1, 268
- Machine learning-derived gut microbiome signature predicts fatty liver disease in the presence of insulin resistance Scientific Reports, 2022, v.12 no.1, 21842
- Sex-specific associations between gut microbiota and skeletal muscle mass in a population-based study Journal of Cachexia, Sarcopenia and Muscle, 2022, v.13 no.6, 2908-2919
- Whole-Genome Sequencing Reveals Age-Specific Changes in the Human Blood Microbiota Journal of Personalized Medicine, 2022, v.12 no.6, 939
- Correlation between Gut Microbiota and Six Facets of Neuroticism in Korean Adults JOURNAL OF PERSONALIZED MEDICINE, 2021, v.11 no.12, 1246
- Gut Microbiota Composition across Normal Range Prostate-Specific Antigen Levels JOURNAL OF PERSONALIZED MEDICINE, 2021, v.11 no.12, 1381
- Large-scale association analyses identify host factors influencing human gut microbiome composition Nature Genetics, 2021, v.53 no.2, 156-165
- Reversion of gut microbiota during the recovery phase in patients with asymptomatic or mild covid-19: Longitudinal study Microorganisms, 2021, v.9 no.6, 1237
- The power of genetic diversity in genome-wide association studies of lipids Nature, 2021, v.600 no.7890, 675-679
- Variants in NEB and RIF1 genes on chr2q23 are associated with skeletal muscle index in Koreans: genome-wide association study Scientific Reports, 2021, v.11 no.1, 2333
- Butler enables rapid cloud-based analysis of thousands of human genomes NATURE BIOTECHNOLOGY, 2020 , 288-
- Comprehensive molecular characterization of mitochondrial genomes in human cancers Nature Genetics, 2020, v.52 no.3, 342-352
- Differentially Abundant Bacterial Taxa Associated with Prognostic Variables of Crohn's Disease: Results from the IMPACT Study JOURNAL OF CLINICAL MEDICINE, 2020, v.9 no.6, 1748
- Gut microbiota and metabolic health among overweight and obese individuals SCIENTIFIC REPORTS, 2020, v.10 no.1, 19417
- Major Lipids, Apolipoproteins, and Alterations of Gut Microbiota JOURNAL OF CLINICAL MEDICINE, 2020, v.9 no.5, 1589
- Pan-cancer analysis of whole genomes NATURE, 2020, v.578 no.7793, 82-
- Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals Scientific Reports, 2020, v.10 no.1, 9179
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples Nature Communications, 2020, v.11 no.1, 4748
- Sex differences in oncogenic mutational processes Nature Communications, 2020, v.11 no.1, 4330
- Alterations of the Gut Microbiome in Chronic Hepatitis B Virus Infection Associated with Alanine Aminotransferase Level JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.2, 173
- Discovery of donor genotype associated with long-term survival of patients with hematopoietic stem cell transplantation in refractory acute myeloid leukemia LEUKEMIA & LYMPHOMA, 2019, v.60 no.7, 1775-1781
- False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases PLOS ONE, 2019, v.14 no.9, e0222535
- Fecal Microbiota Differences According to the Risk of Advanced Colorectal Neoplasms JOURNAL OF CLINICAL GASTROENTEROLOGY, 2019, v.53 no.3, 197-203
- Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects PLOS ONE, 2019, v.14 no.3, e0213692
- Gut Microbiota and Risk of Persistent Nonalcoholic Fatty Liver Diseases JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.8, 1089
- Landscape of Actionable Genetic Alterations Profiled from 1,071 Tumor Samples in Korean Cancer Patients Cancer research and treatment : official journal of Korean Cancer Association, 2019, v.51 no.1, 211-222
- Oncogenic effects of germline variants in lysosomal storage disease genes GENETICS IN MEDICINE, 2019, v.21 no.12, 2695-2705
- Physiologic intestinal F-18-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer SCIENTIFIC REPORTS, 2019, v.9, 18273
- The Impact of Cholecystectomy on the Gut Microbiota: A Case-Control Study JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.1, 79
- The Relationship between Platelet Count and Host Gut Microbiota: A Population-Based Retrospective Cross-Sectional Study JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.2, 230
- Association between Cigarette Smoking Status and Composition of Gut Microbiota: Population-Based Cross-Sectional Study JOURNAL OF CLINICAL MEDICINE, 2018, v.7 no.9, 282
- Association between Neutrophil-to-Lymphocyte Ratio and Gut Microbiota in a Large Population: a Retrospective Cross-Sectional Study SCIENTIFIC REPORTS, 2018, v.8, 16031
- Correlation between gut microbiota and personality in adults: A cross-sectional study BRAIN BEHAVIOR AND IMMUNITY, 2018, v.69, 374-385
- Development of the variant calling algorithm, ADIScan, and its use to estimate discordant sequences between monozygotic twins NUCLEIC ACIDS RESEARCH, 2018, v.46 no.15, e92
- Identification of Novel Functional Variants of SIN3A and SRSF1 among Somatic Variants in Acute Myeloid Leukemia Patients MOLECULES AND CELLS, 2018, v.41 no.5, 465-475
- Imaging genotyping of functional signaling pathways in lung squamous cell carcinoma using a radiomics approach Scientific Reports, 2018, v.8 no.1, 3284
- Integrated genome sizing (IGS) approach for the parallelization of whole genome analysis BMC Bioinformatics, 2018, v.19 no.1, 462
- Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative MICROBIOME, 2018, v.6, 101
- Rosacea and its association with enteral microbiota in Korean females EXPERIMENTAL DERMATOLOGY, 2018, v.27 no.1, 37-42
- Comparative analysis of gut microbiota associated with body mass index in a large Korean cohort BMC Microbiology, 2017, v.17 no.1
- Gut microbiota and physiologic bowel F-18-FDG uptake EJNMMI RESEARCH, 2017, v.7
- HLAscan: genotyping of the HLA region using next-generation sequencing data BMC BIOINFORMATICS, 2017, v.18
- Identification of somatic mutations using whole-exome sequencing in Korean patients with acute myeloid leukemia BMC MEDICAL GENETICS, 2017, v.18
- Meta-analysis of genome-wide SNP- A nd pathway-based associations for facets of neuroticism Journal of Human Genetics, 2017, v.62 no.10, 903-909
- Risk prediction of pulmonary tuberculosis using genetic and conventional risk factors in adult Korean population PLOS ONE, 2017, v.12 no.3
- The effect of probiotics, antibiotics, and antipyretic analgesics on gut microbiota modification Journal of Bacteriology and Virology, 2017, v.47 no.1, 64-74
- Direct and Indirect Effects of Five Factor Personality and Gender on Depressive Symptoms Mediated by Perceived Stress PLOS ONE, 2016, v.11 no.4
- SLC29A1 (ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia Cancer Chemotherapy and Pharmacology, 2016, v.78 no.3, 1-8
- Association between personality traits and sleep quality in young Korean women PLoS ONE, 2015, v.10 no.6
- Background Intestinal F-18-FDG Uptake Is Related to Serum Lipid Profile and Obesity in Breast Cancer Patients PLOS ONE, 2015, v.10 no.11
- Cytidine deaminase polymorphisms and worse treatment response in normal karyotype AML Journal of Human Genetics, 2015, v.60 no.12, 749-754
- Family-Based Association Study of Pulmonary Function in a Population in Northeast Asia PLOS ONE, 2015, v.10 no.10
- GWA meta-analysis of personality in Korean cohorts Journal of Human Genetics, 2015, v.60 no.8, 455-460
- Genome-wide association study identified new susceptibility loci for polycystic ovary syndrome HUMAN REPRODUCTION, 2015, v.30 no.3, 723-731
- Genomic profile of AML-ETO rearranged acute myeloid leukemia CANCER RESEARCH, 2015, v.75
- Pathway Analysis Based on a Genome-Wide Association Study of Polycystic Ovary Syndrome PLOS ONE, 2015, v.10 no.8
- Pathway analysis of genome-wide association datasets of personality traits GENES BRAIN AND BEHAVIOR, 2015, v.14 no.4, 345-356
- Some personality traits converge gradually by long-term partnership through the lifecourse - Genetic and environmental structure of Cloninger's temperament and character dimensions Journal of Psychiatric Research, 2015, v.63, 43-49
- Association between Blood Lipid Levels and Personality Traits in Young Korean Women PLOS ONE, 2014, v.9 no.9
- Association between extraversion personality and abnormal glucose regulation in young Korean women ACTA DIABETOLOGICA, 2014, v.51 no.3, 421-427
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility NATURE GENETICS, 2014, v.46 no.3, 234-
- Genomic profile analysis of diffuse-type gastric cancers GENOME BIOLOGY, 2014, v.15
- Pathway Analysis of Metabolic Syndrome Using a Genome-Wide Association Study of Korea Associated Resource (KARE) Cohorts Genomics & Informatics, 2014, 제12권 4호, 195-202
- Personality Traits and Body Mass Index in a Korean Population PLOS ONE, 2014, v.9 no.3, Article ID e90516
- [학술지논문] Butler enables rapid cloud-based analysis of thousands of human genomes NATURE BIOTECHNOLOGY, 2020, v.38 no.3 , 288-288
- [학술지논문] Comprehensive molecular characterization of mitochondrial genomes in human cancers NATURE GENETICS, 2020, v.52 no.3 , 342-342
- [학술지논문] Differentially Abundant Bacterial Taxa Associated with Prognostic Variables of Crohn's Disease: Results from the IMPACT Study JOURNAL OF CLINICAL MEDICINE, 2020, v.9 no.6 , 1748-1748
- [학술지논문] Gut microbiota and metabolic health among overweight and obese individuals SCIENTIFIC REPORTS, 2020, v.10 no.1 , 19417-19417
- [학술지논문] Major Lipids, Apolipoproteins, and Alterations of Gut Microbiota JOURNAL OF CLINICAL MEDICINE, 2020, v.9 no.5 , 1589-1589
- [학술지논문] Pan-cancer analysis of whole genomes NATURE, 2020, v.578 no.7793 , 82-93
- [학술지논문] Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals SCIENTIFIC REPORTS, 2020, v.10 no.1 , 9179-9179
- [학술지논문] Alterations of the Gut Microbiome in Chronic Hepatitis B Virus Infection Associated with Alanine Aminotransferase Level JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.2 , 173-173
- [학술지논문] Characterization of the Blood Microbiota in Korean Females with Rosacea DERMATOLOGY, 2019, v.235 no.3 , 255-259
- [학술지논문] Discovery of donor genotype associated with long-term survival of patients with hematopoietic stem cell transplantation in refractory acute myeloid leukemia LEUKEMIA & LYMPHOMA, 2019, v.60 no.7 , 1775-1781
- [학술지논문] False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases PLOS ONE, 2019, v.14 no.9 , 0222535-0222535
- [학술지논문] Fecal Microbiota Differences According to the Risk of Advanced Colorectal Neoplasms JOURNAL OF CLINICAL GASTROENTEROLOGY, 2019, v.53 no.3 , 197-203
- [학술지논문] Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects PLOS ONE, 2019, v.14 no.3 , 1-15
- [학술지논문] Gut Microbiota and Risk of Persistent Nonalcoholic Fatty Liver Diseases JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.8 , 1089-1089
- [학술지논문] Oncogenic effects of germline variants in lysosomal storage disease genes GENETICS IN MEDICINE, 2019, v.21 no.12 , 2695-2705
- [학술지논문] Physiologic intestinal F-18-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer SCIENTIFIC REPORTS, 2019, v.9 no.0 , 18273-18273
- [학술지논문] The Impact of Cholecystectomy on the Gut Microbiota: A Case-Control Study JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.1 , 79-79
- [학술지논문] The Relationship between Platelet Count and Host Gut Microbiota: A Population-Based Retrospective Cross-Sectional Study JOURNAL OF CLINICAL MEDICINE, 2019, v.8 no.2 , 230-230
Courses
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2021-1st
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Molecular Cell Biology Ⅰ
- Subject No 34353Class No 01
- 2Year ( 3Credit , 3Hour) Wed 4~5
- Major Requisite
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Introduction to Medicine
- Subject No 37588Class No 01
- 1Year ( 2.5Credit , 48Hour)
- Major Requisite
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Metabolism and Nutrition
- Subject No 37594Class No 01
- 1Year ( 2.5Credit , 52Hour)
- Major Requisite
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Academic Background
Seoul Nat'l Univ. 의학박사(의학과)