연구실적

• BEAR: A Novel Virtual Screening Method Based on Large-Scale Bioactivity Data JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, v.63 no.5
  SCIE Scopus dColl.
• COVID-19 drugs: potential interaction with ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein Journal of Pharmaceutical Investigation, 2023, v.53 no.2, 191-212
  SCIE Scopus KCI dColl.
• Digestive enzyme supplementation in prescription drugs, over-the-counter drugs, and enzyme foods Journal of Pharmaceutical Investigation, 2023, v.53 no.3, 343-355
  SCIE Scopus KCI dColl.
• Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers Journal of Advanced Research, 2023, v.47, 173-187
  SCIE Scopus dColl.
• Population pharmacokinetics and model-based dosing optimization of teicoplanin in elderly critically ill patients with pneumonia Journal of Critical Care, 2023, v.78, 154402
  SCIE Scopus dColl.
• Development and evaluation of a digestive formulation using a microbial enzyme for treatment of dyspepsia Journal of Pharmaceutical Investigation, 2022, v.52 no.5, 601-609
  SCIE Scopus KCI dColl.
• Discovery of (E)-3-(3-((2-Cyano-4' -dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis JOURNAL OF MEDICINAL CHEMISTRY, 2022, v.65 no.14, 9974-10000
  SCIE Scopus dColl.
• Discovery of a NADPH oxidase inhibitor, (E)-3-cyclohexyl-5-(4-((2-hydroxyethyl)(methyl)amino)benzylidene)-1-methyl-2-thioxoimidazolidin-4-oneone, as a novel therapeutic for Parkinson's disease European Journal of Medicinal Chemistry, 2022, v.244, 114854
  SCIE Scopus dColl.
• Drug-like small molecule HSP27 functional inhibitor sensitizes lung cancer cells to gefitinib or cisplatin by inducing altered cross-linked Hsp27 dimers Pharmaceutics, 2021, v.13 no.5, 630
  SCIE Scopus dColl.
• Dual Inhibition of P-gp and BCRP Improves Oral Topotecan Bioavailability in Rodents PHARMACEUTICS, 2021, v.13 no.4, 559
  SCIE Scopus dColl.
• Optimization, validation, and comparison of a rapid method for the quantification of insulin-like growth factor 1 in serum using liquid chromatography–high-resolution mass spectrometry Drug Testing and Analysis, 2021, v.13 no.2, 451-459
  SCIE Scopus dColl.
• Quantification of teicoplanin using the hplc-uv method for clinical applications in critically ill patients in Korea Pharmaceutics, 2021, v.13 no.4, 572
  SCIE Scopus dColl.
• Structural Requirements of 1-(2-Pyridinyl)-5-pyrazolones for Disproportionation of Boronic Acids MOLECULES, 2021, v.26 no.22, 6814
  SCIE Scopus dColl.
• Design of a Novel Theranostic Nanomedicine (III): Synthesis and Physicochemical Properties of Tumor-Targeting Cisplatin Conjugated to a Hydrophilic Polyphosphazene INTERNATIONAL JOURNAL OF NANOMEDICINE, 2020, v.15, 981-990
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• Synthesis, biological evaluation and molecular modelling of 2,4-disubstituted-5-(6-alkylpyridin-2-yl)-1H-imidazoles as ALK5 inhibitors JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2020, v.35 no.1, 702-712
  SCIE Scopus dColl.
• Effects of Piperazine Derivative on Paclitaxel Pharmacokinetics PHARMACEUTICS, 2019, v.11 no.1, 23
  SCIE Scopus dColl.
• Pharmacokinetic Study of NADPH Oxidase Inhibitor Ewha-18278, a Pyrazole Derivative PHARMACEUTICS, 2019, v.11 no.9, 482
  SCIE Scopus dColl.
• Pharmacokinetic alteration of paclitaxel by ferulic acid derivative Pharmaceutics, 2019, v.11 no.11, 593
  SCIE Scopus dColl.
• Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine BIOMATERIALS, 2018, v.156, 172-193
  SCIE Scopus dColl.
• Intestinal P-glycoprotein inhibitors, benzoxanthone analogues JOURNAL OF PHARMACY AND PHARMACOLOGY, 2018, v.70 no.2, 234-241
  SCIE Scopus dColl.
• Menopausal hormone therapy and the risk of breast cancer by histological type and race: a meta-analysis of randomized controlled trials and cohort studies BREAST CANCER RESEARCH AND TREATMENT, 2018, v.170 no.3, 667-675
  SCIE Scopus dColl.
• Regulation of endogenic metabolites by rosuvastatin in hyperlipidemia patients: An integration of metabolomics and lipidomics CHEMISTRY AND PHYSICS OF LIPIDS, 2018, v.214, 69-83
  SCIE Scopus dColl.
• Design of theranostic nanomedicine (II): synthesis and physicochemical properties of a biocompatible polyphosphazene-docetaxel conjugate INTERNATIONAL JOURNAL OF NANOMEDICINE, 2017, v.12
  SCIE Scopus dColl.
• Effects of Adamantyl Derivatives on Pharmacokinetic Behavior of Paclitaxel in Rats BIOMOLECULES & THERAPEUTICS, 2017, v.25 no.5, 553-558
  SCIE Scopus KCI dColl.
• Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor European Journal of Medicinal Chemistry, 2017, v.127, 318-333
  SCIE Scopus dColl.
• Sensitization of lung cancer cells by altered dimerization of HSP27 Oncotarget, 2017, v.8 no.62, 105372-105382
  SCIE Scopus dColl.
• 1H-Nuclear magnetic resonance-based metabolic profiling of nonsteroidal anti-inflammatory drug-induced adverse effects in rats Journal of Pharmaceutical and Biomedical Analysis, 2016, v.129, 492-501
  SCIE Scopus dColl.
• A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase SCIENTIFIC REPORTS, 2016, v.6, 22389
  SCIE Scopus dColl.
• Design of a novel theranostic nanomedicine: Synthesis and physicochemical properties of a biocompatible Polyphosphazene–platinum(II) conjugate International Journal of Nanomedicine, 2016, v.11, 837-851
  Scopus dColl.
• Development of simultaneous analysis of tryptophan metabolites in serum and gastric juice - an investigation towards establishing a biomarker test for gastric cancer diagnosis Biomedical Chromatography, 2016, 12 July 2016
  SCIE Scopus dColl.
• Effective Killing of Cancer Cells Through ROS-Mediated Mechanisms by AMRI-59 Targeting Peroxiredoxin I ANTIOXIDANTS & REDOX SIGNALING, 2016, v.24 no.8, 453-469
  SCIE Scopus dColl.
• Effective killing of cancer cells and regression of tumor growth by K27 targeting sulfiredoxin Free Radical Biology and Medicine, 2016, v.101, 384-392
  SCIE Scopus dColl.
• Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage Free Radical Biology and Medicine, 2016, v.91, 264-274
  SCIE Scopus dColl.
• Xanthone analogues as potent modulators of intestinal P-glycoprotein EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, v.93, 237-245
  SCIE Scopus dColl.
• Development of lipidomic platform and phosphatidylcholine retention time index for lipid profiling of rosuvastatin treated human plasma JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, v.944, 157-165
  SCIE Scopus dColl.
• Discovery of N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197) : A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-beta Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent JOURNAL OF MEDICINAL CHEMISTRY, 2014, v.57 no.10, 4213-4238
  SCIE Scopus dColl.
• Effect of coumarin derivative-mediated inhibition of P-glycoprotein on oral bioavailability and therapeutic efficacy of paclitaxel EUROPEAN JOURNAL OF PHARMACOLOGY, 2014, v.723, 381-388
  SCIE Scopus dColl.
• Na+/H+ Exchanger Regulatory Factor 3 Is Critical for Multidrug Resistance Protein 4-Mediated Drug Efflux in the Kidney JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, v.25 no.4, 726-736
  SCIE Scopus dColl.
• Preclinical evaluation of efficacy and stability of docetaxel micelle-encapsulated by a tripodal cyclotriphosphazene amphiphile BIOMEDICINE & PHARMACOTHERAPY, 2014, v.68 no.5, 649-655
  SCIE Scopus dColl.
• Synthesis and properties of a new micellar polyphosphazene-platinum(II) conjugate drug JOURNAL OF INORGANIC BIOCHEMISTRY, 2014, v.140, 45-52
  SCIE Scopus dColl.
• Aripiprazole-montmorillonite: A new organic-inorganic nanohybrid material for biomedical applications Chemistry - A European Journal, 2013, v.19 no.15, 4869-4875
  SCIE Scopus dColl.
• Effects of single or repeated silymarin administration on pharmacokinetics of risperidone and its major metabolite, 9-hydroxyrisperidone in rats Xenobiotica, 2013, v.43 no.3, 303-310
  SCIE Scopus dColl.
• Identification of a New Hexenoic Acid Glycoside and the RSV Principles from Vitis vinifera cv. Muscat of Alexandria Bulletin of the Korean Chemical Society, 2013, v.34 no.6, 1906-1908
  SCIE KCI Scopus dColl.
• In Vitro and in Vivo Evaluation of Phenylbutenoid Dimers as Inhibitors of P-Glycoprotein JOURNAL OF NATURAL PRODUCTS, 2013, v.76 no.12, 2277-2281
  SCIE Scopus dColl.
• Synthesis and physicochemical properties of new tripodal amphiphiles bearing fatty acids as a hydrophobic group Bioorganic and Medicinal Chemistry Letters, 2013, v.23 no.6, 1763-1767
  SCIE Scopus dColl.
• A nanohybrid system for taste masking of sildenafil International Journal of Nanomedicine, 2012, v.7, 1635-1649
  Scopus dColl.
• Determination of daumone in mouse plasma by HPLC/MS-MS Biomedical Chromatography, 2012, v.26 no.2, 152-155
  SCIE Scopus dColl.
• Effects of formulation on pharmacokinetics of docetaxel in rats Journal of Pharmaceutical Investigation, 2012, v.42 no.1, 51-55
  KCI Scopus dColl.
• Effects of silymarin and formulation on the oral bioavailability of paclitaxel in rats European Journal of Pharmaceutical Sciences, 2012, v.45 no.3, 296-301
  SCIE Scopus dColl.
• Evaluation of pharmacokinetic differences of acetaminophen in pseudo germ-free rats Biopharmaceutics and Drug Disposition, 2012, v.33 no.6, 292-303
  SCIE Scopus dColl.
• Nuclear magnetic resonance-based metabolomics for prediction of gastric damage induced by indomethacin in rats Analytica Chimica Acta, 2012, v.722, 87-94
  SCIE Scopus dColl.
• Preclinical study of a potent P-glycoprotein and cytochrome P450 enzyme inducer rifampicin changing pharmacokinetic parameters of risperidone and its metabolite, 9-hydroxyrisperidone, using a rat model Journal of Pharmaceutical Investigation, 2012, v.42 no.6, 345-351
  KCI Scopus dColl.
• Quantitative analysis of acetaminophen and its six metabolites in rat plasma using liquid chromatography/tandem mass spectrometry Biomedical Chromatography, 2012, v.26 no.12, 1596-1604
  SCIE Scopus dColl.
• Stable and efficient delivery of docetaxel by micelle-encapsulation using a tripodal cyclotriphosphazene amphiphile International Journal of Pharmaceutics, 2012, v.422 no.41276, 374-380
  SCIE Scopus dColl.
• [학술지논문] Population pharmacokinetics and model-based dosing optimization of teicoplanin in elderly critically ill patients with pneumonia JOURNAL OF CRITICAL CARE, 2023, v.78 no.0 , 154402-154402
  SCIE
• [지적재산권] 알콕시페닐프로펜온 유도체 또는 이의 약학적으로 허용가능한 염 및 이를 유효성분으로 함유하는 다약제 내성 억제용 약학적 조성물 국내 : 특허, 등록, 10-1427291, 2014

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